Vitamin D deficiency in a subfertility population and the impact of COVID‐19 lockdowns DOI Creative Commons
Catherine Windrim, Daniel Kane,

Grainne Kelleher

et al.

International Journal of Gynecology & Obstetrics, Journal Year: 2025, Volume and Issue: unknown

Published: April 7, 2025

Abstract Objective To evaluate the burden of vitamin D deficiency in female patients attending a fertility clinic tertiary referral center, assess temporal trends—including potential impact COVID‐19 lockdowns—and explore socioeconomic disparities levels. Methods This retrospective cohort study analyzed measurements from 765 (mean age 35.7 ± 5.8 years) between March 2010 and May 2022. Vitamin status was categorized as deficient (<30 nmol/L), insufficient (30–50 or normal (>50 nmol/L). Comparative analyses examined pre‐ post‐COVID periods healthcare funding status. Results Overall, 39.9% ( n = 305) exhibited suboptimal levels, with 8.8% 67) 31.1% 238) insufficient. Mean serum 25(OH)D 62.8 27.4 nmol/L. No statistically significant difference observed pre‐COVID (44.2% suboptimal) (38.1% (OR 0.78, 95% CI: 0.57–1.06, P 0.110). However, marked seasonal variation identified, winter values significantly lower than summer (45.3 24.6 vs. 72.1 28.3 nmol/L, < 0.001). Furthermore, state‐funded had higher rate (50.2%, 107) compared to self‐funded (35.9%, 198, Conclusion Our findings demonstrate high prevalence levels subfertility population, fluctuations notable disparities. Despite initial concerns, lockdown measures did not appear adversely affect overall These results support incorporation routine screening infertility evaluations implementation targeted supplementation, particularly economically vulnerable groups during months.

Language: Английский

Vitamin D deficiency in a subfertility population and the impact of COVID‐19 lockdowns DOI Creative Commons
Catherine Windrim, Daniel Kane,

Grainne Kelleher

et al.

International Journal of Gynecology & Obstetrics, Journal Year: 2025, Volume and Issue: unknown

Published: April 7, 2025

Abstract Objective To evaluate the burden of vitamin D deficiency in female patients attending a fertility clinic tertiary referral center, assess temporal trends—including potential impact COVID‐19 lockdowns—and explore socioeconomic disparities levels. Methods This retrospective cohort study analyzed measurements from 765 (mean age 35.7 ± 5.8 years) between March 2010 and May 2022. Vitamin status was categorized as deficient (<30 nmol/L), insufficient (30–50 or normal (>50 nmol/L). Comparative analyses examined pre‐ post‐COVID periods healthcare funding status. Results Overall, 39.9% ( n = 305) exhibited suboptimal levels, with 8.8% 67) 31.1% 238) insufficient. Mean serum 25(OH)D 62.8 27.4 nmol/L. No statistically significant difference observed pre‐COVID (44.2% suboptimal) (38.1% (OR 0.78, 95% CI: 0.57–1.06, P 0.110). However, marked seasonal variation identified, winter values significantly lower than summer (45.3 24.6 vs. 72.1 28.3 nmol/L, < 0.001). Furthermore, state‐funded had higher rate (50.2%, 107) compared to self‐funded (35.9%, 198, Conclusion Our findings demonstrate high prevalence levels subfertility population, fluctuations notable disparities. Despite initial concerns, lockdown measures did not appear adversely affect overall These results support incorporation routine screening infertility evaluations implementation targeted supplementation, particularly economically vulnerable groups during months.

Language: Английский

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