Current concepts and recent trends in endothelial keratoplasty DOI
Prateek Nishant, Bharat Gurnani, Prabhakar Singh

et al.

World Journal of Transplantation, Journal Year: 2025, Volume and Issue: 15(2)

Published: Feb. 21, 2025

Endothelial keratoplasty (EK) is defined as an umbrella term comprising methods for selective surgical replacement of corneal endothelium and adjacent tissue, which retains healthy portions a patient's cornea while replacing diseased innermost layer(s) with donor to achieve dehydration transparency before the onset irreversible stromal edema permanent loss clarity. Recently, pathophysiology decompensation increasingly being researched upon. Consequent improvement in pharmacotherapy progressively leading reduction indications EK. In addition, EK techniques have progressed towards using thinner optimizing visual outcomes. Improvements enabled better tissue formulation, usage, attachment, modifications enhanced utilization difficult clinical scenarios lowering failure rejection. However, challenges are encountered various complex including eyes prior intraocular surgery, anterior chamber anatomy, glaucoma, ocular surface disease etc. These complexities demand tailored strategies, graft handling, instrumentation, postoperative management ensure success. Attention these details addressing patient-specific factors can help improve outcomes cases. The choice procedure depends on multiple factors, surgeon's experience, specific scenario. This review article encompasses recent developments this field presenting comprehensive picture our modern understanding indications, contraindications, techniques, situations, community aspects future directions pertaining

Language: Английский

Current concepts and recent trends in endothelial keratoplasty DOI
Prateek Nishant, Bharat Gurnani, Prabhakar Singh

et al.

World Journal of Transplantation, Journal Year: 2025, Volume and Issue: 15(2)

Published: Feb. 21, 2025

Endothelial keratoplasty (EK) is defined as an umbrella term comprising methods for selective surgical replacement of corneal endothelium and adjacent tissue, which retains healthy portions a patient's cornea while replacing diseased innermost layer(s) with donor to achieve dehydration transparency before the onset irreversible stromal edema permanent loss clarity. Recently, pathophysiology decompensation increasingly being researched upon. Consequent improvement in pharmacotherapy progressively leading reduction indications EK. In addition, EK techniques have progressed towards using thinner optimizing visual outcomes. Improvements enabled better tissue formulation, usage, attachment, modifications enhanced utilization difficult clinical scenarios lowering failure rejection. However, challenges are encountered various complex including eyes prior intraocular surgery, anterior chamber anatomy, glaucoma, ocular surface disease etc. These complexities demand tailored strategies, graft handling, instrumentation, postoperative management ensure success. Attention these details addressing patient-specific factors can help improve outcomes cases. The choice procedure depends on multiple factors, surgeon's experience, specific scenario. This review article encompasses recent developments this field presenting comprehensive picture our modern understanding indications, contraindications, techniques, situations, community aspects future directions pertaining

Language: Английский

Citations

0