
Biomedicines, Journal Year: 2025, Volume and Issue: 13(5), P. 1113 - 1113
Published: May 4, 2025
The role of blind endometrial sampling, in the era hysteroscopy-guided biopsy, can be only considered as a screening tool or first-line approach if hysteroscopy cannot performed for whatever reason. Several devices are available, with Perma (a sharp-edged spatula sliding inside flexible cannula) being one them. Objectives: aims this study were to compare concordance visual and influence operators’ experience on results. Materials Methods: Women undergoing invited undergo biopsy well. If accepted, sampling was before there no cervical dilatation (as an office setting). operator randomly chosen between expert (two staff members) non-expert residents) operators. All cases collected at AOU Maggiore della Carità, Novara, Italy. Categorical variables presented number percentage (%) continuous mean ± SD. association categorical evaluated using Fisher’s exact test. Clinical outcomes analyzed, results first compared within same patient subsequent doctors’ group (inter- intra-variation) terms Cohen’s Kappa. Results: 82 women both Perma. A sensitivity 81.8% specificity 100% found when (the gold standard). comparison valid vs. invalid samples sufficient evaluable tissue not significant (p = 0.583). There statistical associations body mass index, parity, previous intrauterine surgery related Kappa non-experts 0.43 (moderate), experts 0.30 (fair), highest non- (0.68 substantial). represents pragmatic diagnostic tool, which could also used outpatient.
Language: Английский