Prevalence of potentially inappropriate medications among elderly patients with diabetes – study based on STOPP/START criteria DOI Creative Commons
Petya Milushewa, Kristina Kosanova, Petar Nikolov

et al.

Pharmacia, Journal Year: 2023, Volume and Issue: 70(3), P. 817 - 823

Published: Sept. 19, 2023

Objective : The prevalence of drug-related problems in elderly patients is a concerning issue that can lead to elevated morbidity, mortality, and health care resource utilisation. This study focuses on the significance addressing diabetes context an ageing population, where individuals face higher risks comorbidities mortality. main objective this was assess potentially inappropriate medications (PIMs) potential prescribing omissions (PPOs) among with Bulgaria, using explicit STOPP/START criteria, version 2. By evaluating appropriateness drug prescriptions specific patient aims shed light areas require optimisation enhance safety treatment outcomes. Materials methods A national prospective questionnaire conducted Bulgaria aged over 65 years. research 25 randomly selected pharmacies. supports use criteria based clinical information provided. total 133 T1DM or T2DM participated study. evaluation performed 131 patients. sStatistical differences demographics medication numbers between without PIMs PPOs were assessed Chi-square test, p-value ≤ 0.05 considered statistically significant. Results pharmacotherapy assessed, it found 57% them had polypharmacy. Among 90 identified, indicating 66% prescribing. Notably, associated long-acting sulfonylureas (n=10) beta-blockers (n=13). Applying START revealed 67 patients, representing 50% population. However, no detected pharmacotherapy. Furthermore, significant relationship observed number PIMs, as evidenced by chi-square test result close zero, statistical significance. Conclusion high Bulgaria. Endocrine disorders contribute 26% PIMs. As Bulgaria’s population faces increasing challenges, effective management strategies are crucial. These findings underscore practises disease control prevent complications.

Language: Английский

Potentially inappropriate medication among older patients with diabetic kidney disease DOI Creative Commons

Yuping Wang,

Jie Zhu, Luchen Shan

et al.

Frontiers in Pharmacology, Journal Year: 2023, Volume and Issue: 14

Published: Feb. 8, 2023

Objective: Potentially inappropriate medications (PIM) contribute to poor outcomes in older patients, making it a widespread health problem. The study explored the occurrence and risk factors of PIM diabetic kidney disease (DKD) patients during hospitalization investigated whether polypharmacy was associated with it. Methods: Retrospective analysis ≥ 65 years old diagnosed DKD from July December 2020; evaluated according American Beers Criteria (2019). Factors statistical significance univariate were included Logistic multivariate explore potential related PIM. Results: Included 186 65.6% had PIM, 300 items confirmed. highest incidence 41.7% for drugs that should be carefully used by older, followed 35.3% avoided hospitalization. diseases or symptoms, drug interactions avoid, avoid reduce dose renal insufficiency 6.3%, 4.0% 12.7%, respectively. high diuretics (35.0%), benzodiazepines (10.7%) peripheral ɑ1 blockers (8.7%). Compared hospitalization, there 26% increased at discharge. Multivariate regression showed an independent factor OR = 4.471 (95% CI: 2.378, 8.406). Conclusion: hospitalized is high; we pay more attention problem these patients. Pharmacists identifying subtypes may facilitate reduction

Language: Английский

Citations

0
Barriers to deprescribing proton pump inhibitors and how to overcome them DOI

Rebecca Field,

Hilary Field

Gastrointestinal Nursing, Journal Year: 2023, Volume and Issue: 21(3), P. 22 - 28

Published: April 2, 2023

Proton pump Inhibitors are one of the most commonly prescribed medications in UK, and since availability over-the-counter proton Inhibitors, true number patients taking is unknown. With boom Inhibitor prescriptions, increasing numbers being outside recommended guidelines, beyond advised course length. Like all medications, not innocuous have a range side effects, therefore, clinicians need to consider deprescribing them. There multiple barriers deprescribing, so roles gastrointestinal nurse these develop strategies as how they can be overcome.

Language: Английский

Citations

0
Examining inappropriate medication in UK primary care for type 2 diabetes patients with polypharmacy DOI Creative Commons
Maria Luisa Faquetti,

Géraldine Frey,

Dominik Stämpfli

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: May 28, 2023

Abstract Aims To estimate the prevalence of potentially inappropriate prescriptions (PIPs) in patients starting their first non-insulin antidiabetic treatment (NIAD) using two explicit process measures appropriateness prescribing UK primary care, stratified by age and polypharmacy status. Methods A descriptive cohort study between 2016 2019 was conducted to assess PIPs aged ≥45 years at start NIAD, The American Geriatrics Society (AGS) Beers criteria 2015 used for older (≥65 years) Prescribing Optimally Middle-age People’s Treatments (PROMPT) middle-aged (45-64 patients. Prevalence overall individual reported IQVIA Medical Research Data incorporating THIN, a Cegedim Database anonymised electronic health records UK. Results Among 28,604 initiating NIADs, 18,494 (64.7%) received polypharmacy. In with polypharmacy, 39.6% 22.7%, respectively, ≥1 PIPs. At level, long-term PPI use strong opioid without laxatives were most frequent among (11.1% 4.1%, respectively). Conclusions This revealed that NIAD receiving have potential pharmacotherapy optimisation.

Language: Английский

Citations

0
General Principles of Pharmacologic Therapy DOI
Ken Inada, Shigeto Yamawaki,

Shigenobu Kanba

et al.

Springer eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 1 - 18

Published: Jan. 1, 2023

Language: Английский

Citations

0
Prevalence of potentially inappropriate medications among elderly patients with diabetes – study based on STOPP/START criteria DOI Creative Commons
Petya Milushewa, Kristina Kosanova, Petar Nikolov

et al.

Pharmacia, Journal Year: 2023, Volume and Issue: 70(3), P. 817 - 823

Published: Sept. 19, 2023

Objective : The prevalence of drug-related problems in elderly patients is a concerning issue that can lead to elevated morbidity, mortality, and health care resource utilisation. This study focuses on the significance addressing diabetes context an ageing population, where individuals face higher risks comorbidities mortality. main objective this was assess potentially inappropriate medications (PIMs) potential prescribing omissions (PPOs) among with Bulgaria, using explicit STOPP/START criteria, version 2. By evaluating appropriateness drug prescriptions specific patient aims shed light areas require optimisation enhance safety treatment outcomes. Materials methods A national prospective questionnaire conducted Bulgaria aged over 65 years. research 25 randomly selected pharmacies. supports use criteria based clinical information provided. total 133 T1DM or T2DM participated study. evaluation performed 131 patients. sStatistical differences demographics medication numbers between without PIMs PPOs were assessed Chi-square test, p-value ≤ 0.05 considered statistically significant. Results pharmacotherapy assessed, it found 57% them had polypharmacy. Among 90 identified, indicating 66% prescribing. Notably, associated long-acting sulfonylureas (n=10) beta-blockers (n=13). Applying START revealed 67 patients, representing 50% population. However, no detected pharmacotherapy. Furthermore, significant relationship observed number PIMs, as evidenced by chi-square test result close zero, statistical significance. Conclusion high Bulgaria. Endocrine disorders contribute 26% PIMs. As Bulgaria’s population faces increasing challenges, effective management strategies are crucial. These findings underscore practises disease control prevent complications.

Language: Английский

Citations

0