Relationship between Structure and Rheology of Hydrogels for Various Applications

Gels, Journal Year: 2021, Volume and Issue: 7(4), P. 255 - 255

Published: Dec. 9, 2021

Hydrogels have gained a lot of attention with their widespread use in different industrial applications. The versatility the synthesis and nature precursor reactants allow for varying range hydrogels mechanical rheological properties. Understanding behavior relationship between chemical structure resulting properties is crucial, focus this review. Specifically, we include detailed discussion on correlation characteristics possible Different tests such as time, temperature frequency sweep, among others, are described results those reported. most prevalent applications also discussed.

Language: Английский

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Extraction and application of keratin from natural resources: a review

3 Biotech, Journal Year: 2021, Volume and Issue: 11(5)

Published: April 16, 2021

Language: Английский

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A Review on Electrospun Nanofibers Based Advanced Applications: From Health Care to Energy Devices

Polymers, Journal Year: 2021, Volume and Issue: 13(21), P. 3746 - 3746

Published: Oct. 29, 2021

Electrospun nanofibers have been exploited in multidisciplinary fields with numerous applications for decades. Owing to their interconnected ultrafine fibrous structure, high surface-to-volume ratio, tortuosity, permeability, and miniaturization ability along the benefits of lightweight, porous nanofibrous they extensively utilized various research nanofiber technologies paved unprecedented advancements new innovations discoveries several application including energy devices biomedical environmental appliances. This review article focused on providing a comprehensive overview related recent health care while emphasizing importance uniqueness utilizing nanofibers. A brief description regarding effect electrospinning techniques, setup modifications, parameters optimization morphology was also provided. The is concluded short discussion current challenges future perspectives.

Language: Английский

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Progress of Electrospun Nanofibrous Carriers for Modifications to Drug Release Profiles

Journal of Functional Biomaterials, Journal Year: 2022, Volume and Issue: 13(4), P. 289 - 289

Published: Dec. 9, 2022

Electrospinning is an advanced technology for the preparation of drug-carrying nanofibers that has demonstrated great advantages in biomedical field. Electrospun nanofiber membranes are widely used field drug administration due to their such as large specific surface area and similarity extracellular matrix. Different electrospinning technologies can be prepare different structures, those with a monolithic structure, core–shell Janus or porous structure. It also possible controlled-release functions, sustained release, delayed biphasic targeted release. This paper elaborates on drug-loaded using various concludes mechanisms behind controlled release drugs.

Language: Английский

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Poly(lactic acid)-Based Electrospun Fibrous Structures for Biomedical Applications

Applied Sciences, Journal Year: 2022, Volume and Issue: 12(6), P. 3192 - 3192

Published: March 21, 2022

Poly(lactic acid)(PLA) is an aliphatic polyester that can be derived from natural and renewable resources. Owing to favorable features, such as biocompatibility, biodegradability, good thermal mechanical performance, processability, PLA has been considered one of the most promising biopolymers for biomedical applications. Particularly, electrospun nanofibers with distinguishing characteristics, similarity extracellular matrix, large specific surface area high porosity small pore size tunable properties diverse applications, have recently given rise advanced spillovers in medical area. A variety PLA-based nanofibrous structures explored purposes, wound dressing, drug delivery systems, tissue engineering scaffolds. This review highlights recent advances electrospinning It also gives a comprehensive discussion about approaches suggested optimizing towards design devices appropriate physical, biological functions.

Language: Английский

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Exploring the contribution of pro-inflammatory cytokines to impaired wound healing in diabetes

Frontiers in Immunology, Journal Year: 2023, Volume and Issue: 14

Published: July 27, 2023

Impaired wound healing is the most common and significant complication of Diabetes. While other complications Diabetes have better treatment options, diabetic wounds remain a burden as they can cause pain suffering in patients. Wound closure repair are orchestrated by sequence events aided release pro-inflammatory cytokines, which dysregulated cases Diabetes, making environment unfavorable for delaying processes. This concise review provides an overview dysregulation cytokines offers insights into therapeutic outcomes.

Language: Английский

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Inorganic/organic combination: Inorganic particles/polymer composites for tissue engineering applications

Bioactive Materials, Journal Year: 2023, Volume and Issue: 24, P. 535 - 550

Published: Jan. 11, 2023

Biomaterials have ushered the field of tissue engineering and regeneration into a new era with development advanced composites. Among these, composites inorganic materials organic polymers present unique structural biochemical properties equivalent to naturally occurring hybrid systems such as bones, thus are highly desired. The last decade has witnessed steady increase in research on focus being mimicking peculiar inorganic/organic combination nature. In this review, we discuss recent progress use particle/polymer for regenerative medicine. We elaborated advantages over their particle-based composite counterparts. As particles play crucial role defining features capacity composites, review puts special emphasis various types used that covered categorised two broad (1) solid (e.g

Language: Английский

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Advances in Natural Product Extraction Techniques, Electrospun Fiber Fabrication, and the Integration of Experimental Design: A Comprehensive Review

Molecules, Journal Year: 2023, Volume and Issue: 28(13), P. 5163 - 5163

Published: July 2, 2023

The present review explores the growing interest in techniques employed for extracting natural products. It emphasizes limitations of conventional extraction methods and introduces superior non-conventional alternatives, particularly ultrasound-assisted extraction. Characterization quantification bioactive constituents through chromatography coupled with spectroscopy are recommended, while importance method development validation biomarker is underscored. At present, electrospun fibers provide a versatile platform incorporating extracts have extensive potential diverse fields due to their unique structural functional characteristics. Thus, also highlights fabrication containing extracts. preparation biologically active under optimal conditions, including selection safe solvents cost-effective equipment, holds promising pharmaceutical, food, cosmetic industries. Integration experimental design into procedures formulation essential efficient production health applications encapsulating product fibers, such as wound healing, antibacterial activity, antioxidant properties, acknowledging need further exploration optimization this field. findings discussed anticipated serve valuable resource processing industry, enabling utilization affordable environmentally friendly, natural, raw materials.

Language: Английский

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Extracellular Matrix‐Bioinspired Anisotropic Topographical Cues of Electrospun Nanofibers: A Strategy of Wound Healing through Macrophage Polarization

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(12)

Published: Jan. 31, 2024

Abstract The skin serves as the body's outermost barrier and is largest organ, providing protection not only to body but also various internal organs. Owing continuous exposure external factors, it susceptible damage that can range from simple severe, including serious types of wounds such burns or chronic wounds. Macrophages play a crucial role in entire wound‐healing process contribute significantly regeneration. Initially, M1 macrophages infiltrate phagocytose bacteria, debris, dead cells fresh As tissue repair activated, M2 are promoted, reducing inflammation facilitating restoration dermis epidermis regenerate tissue. This suggests extracellular matrix (ECM) promotes cell adhesion, proliferation, migrationand macrophage polarization. Among numerous strategies, electrospinning versatile technique for obtaining ECM‐mimicking structures with anisotropic isotropic topologies micro/nanofibers. Various electrospun biomaterials influence polarization based on their topologies. Moreover, these fibers possess high surface‐area‐to‐volume ratio, promoting effective exchange vital nutrients oxygen, which viability Micro/nanofibers diverse physical chemical properties be tailored polarize toward regeneration wound healing, depending specific requirements. review describes significance micro/nanostructures activating healing.

Language: Английский

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Collagen-Based Nanofibers for Skin Regeneration and Wound Dressing Applications

Polymers, Journal Year: 2021, Volume and Issue: 13(24), P. 4368 - 4368

Published: Dec. 13, 2021

Skin regeneration after an injury is very vital, but this process can be impeded by several factors. Regenerative medicine a developing biomedical field with the potential to decrease need for organ transplant. Wound management challenging, particularly chronic injuries, despite availability of various types wound dressing scaffolds in market. Some dressings that are clinical practice have drawbacks such as poor antibacterial and antioxidant efficacy, mechanical properties, inability absorb excess exudates, require frequent change fails offer suitable moist environment accelerate healing process. Collagen biopolymer major constituent extracellular matrix (ECM), making it interesting polymer development dressings. Collagen-based nanofibers demonstrated properties advantageous both arena skin dressings, low antigenicity, good biocompatibility, hemostatic capability promote cellular proliferation adhesion, non-toxicity. Hence, review will discuss outcomes collagen-based reported from series preclinical trials healing.

Language: Английский

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