Corrosion Reviews,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 23, 2024
Abstract
Over
the
past
two
decades,
research
on
alloys
and
composites
based
Mg,
Fe,
Zn
has
focused
biodegradable
orthopaedic
implants.
Mg-based
materials
face
issues
like
excessive
corrosion
rates
hydrogen
gas
evolution,
while
Fe
Zn-based
show
lower
rates.
However,
these
are
slower
than
optimal
rate,
which
can
be
modified
using
powder
metallurgy
(PM)
manufacturing.
The
PM
process
offers
precise
control
over
porosity
distribution
in
turn
affects
mechanical
properties
of
fabricated
specimen.
highest
rate
i.e.
0.944
mmpy
was
observed
with
alloying
2
wt%
Pd
by
conventional
sintering
technique.
Similarly,
samples
found
to
exhibit
higher
as
compared
microwave
spark
plasma
sintered
PM-fabricated
bone
scaffolds
have
been
investigated
for
in-vitro
osseointegration.
A
(>60
%)
resulted
high
adversely
impacted
cell
proliferation.
This
timely
review
critically
assessed
that
potential
transform
regenerative
medicine
patient
care
redefining
field
Micromachines,
Journal Year:
2023,
Volume and Issue:
14(8), P. 1590 - 1590
Published: Aug. 12, 2023
This
comprehensive
study
investigates
the
micro-milling
of
a
Mg13Sn
alloy,
material
considerable
interest
in
various
high-precision
applications,
such
as
biomedical
implants.
The
main
objective
was
to
explore
optimizations
variable
feed
per
tooth
(fz),
cutting
speed
(Vc),
and
depth
cut
(ap)
parameters
on
key
outcomes
process.
A
unique
experimental
setup
employed,
employing
spindle
capable
achieving
up
60,000
revolutions
minute.
Additionally,
leveraged
linear
slides
backed
by
micro-step
motors
facilitate
precise
axis
movements,
thereby
maintaining
resolution
accuracy
0.1
μm.
Cutting
forces
were
accurately
captured
mini
dynamometer
subsequently
evaluated
based
peak
valley
values
for
Fx
(tangential
force)
Fy
(feed
force).
results
revealed
clear
complex
interplay
between
varied
their
subsequent
impacts
surface
roughness.
An
increase
rate
significantly
increased
forces.
However,
found
decrease
noticeably
with
elevation
speed.
Intriguingly,
tangential
force
(Fx)
consistently
higher
than
(Fy).
Simultaneously,
determined
that
roughness,
denoted
Sa
values,
direct
proportion
rate.
It
also
roughness
decreased
recommends
parameter
combination
fz
=
5
µm/tooth
rate,
Vc
62.8
m/min
speed,
ap
400
µm
maintain
value
less
1
while
ensuring
an
optimal
removal
machining
time.
derived
from
this
offer
vital
insights
into
alloys
contribute
current
body
knowledge
topic.
Materials,
Journal Year:
2024,
Volume and Issue:
17(3), P. 769 - 769
Published: Feb. 5, 2024
Precision
manufacturing
requirements
are
the
key
to
ensuring
quality
and
reliability
of
biomedical
implants.
The
powder
bed
fusion
(PBF)
technique
offers
a
promising
solution,
enabling
creation
complex,
patient-specific
implants
with
high
degree
precision.
This
technology
is
revolutionizing
industry,
paving
way
for
new
era
personalized
medicine.
review
explores
details
3D
printing
its
application
in
field.
It
begins
an
introduction
3D-printing
various
classifications.
Later,
it
analyzes
numerous
fields
which
has
been
successfully
deployed
where
precision
components
required,
including
fabrication
scaffolds
tissue
engineering.
also
discusses
potential
advantages
limitations
using
terms
precision,
customization,
cost
effectiveness.
In
addition,
highlights
current
challenges
prospects
technology.
work
valuable
insights
researchers
engaged
field,
aiming
contribute
advancement
context
applications.
Materials,
Journal Year:
2024,
Volume and Issue:
17(21), P. 5157 - 5157
Published: Oct. 23, 2024
Magnesium
(Mg)
has
attracted
considerable
attention
as
a
biodegradable
material
for
medical
implants
owing
to
its
excellent
biocompatibility,
mitigating
long-term
toxicity
and
stress
shielding.
Nevertheless,
challenges
arise
from
rapid
degradation
low
corrosion
resistance
under
physiological
conditions.
To
overcome
these
challenges,
titanium
(biocompatibility
resistance)
been
integrated
into
Mg.
The
incorporation
of
significantly
improves
mechanical
properties,
thereby
enhancing
performance
in
biological
settings.
Mg–Ti
alloys
are
produced
through
alloying
spark
plasma
sintering
(SPS).
SPS
technique
transforms
powder
mixtures
bulk
materials
while
preserving
structural
integrity,
resulting
enhanced
resistance,
particularly
Mg80-Ti20
alloy
simulated
body
fluids.
Moreover,
revealed
no
more
when
assessed
on
pre-osteoblastic
cells.
Furthermore,
the
ability
Mg–Ti-based
create
composites
with
polymers
such
PLGA
(polylactic-co-glycolic
acid)
widen
their
biomedical
applications
by
regulating
ensuring
pH
stability.
These
promote
temporary
orthopaedic
implants,
offering
initial
load-bearing
capacity
during
healing
process
fractures
without
requiring
second
surgery
removal.
address
scalability
constraints,
further
research
is
necessary
investigate
additional
consolidation
methods
beyond
SPS.
It
essential
evaluate
relationship
between
loading
confirm
adequacy
environments.
This
review
article
highlights
importance
characterization
evaluation
alloys,
reinforcing
applicability
fracture
fixation
various
implants.
Polymers,
Journal Year:
2023,
Volume and Issue:
15(19), P. 3854 - 3854
Published: Sept. 22, 2023
The
utilization
of
materials
in
medical
implants,
serving
as
substitutes
for
non-functional
biological
structures,
supporting
damaged
tissues,
or
reinforcing
active
organs,
holds
significant
importance
modern
healthcare,
positively
impacting
the
quality
life
millions
individuals
worldwide.
However,
certain
implants
may
only
be
required
temporarily
to
aid
healing
process
diseased
injured
tissues
and
tissue
expansion.
Biodegradable
metals,
including
zinc
(Zn),
magnesium
(Mg),
iron,
others,
present
a
new
paradigm
realm
implant
materials.
Ongoing
research
focuses
on
developing
optimized
that
meet
standards,
encompassing
controllable
corrosion
rates,
sustained
mechanical
stability,
favorable
biocompatibility.
Achieving
these
objectives
involves
refining
alloy
compositions
tailoring
processing
techniques
carefully
control
microstructures
properties.
Among
under
investigation,
Mg-
Zn-based
biodegradable
their
alloys
demonstrate
ability
provide
necessary
support
during
regeneration
while
gradually
degrading
over
time.
Furthermore,
essential
elements
human
body,
Mg
Zn
offer
additional
benefits,
promoting
wound
healing,
facilitating
cell
growth,
participating
gene
generation
interacting
with
various
vital
functions.
This
review
provides
an
overview
physiological
function
significance
health
usage
using
scaffolds.
scaffold
qualities,
such
biodegradation,
characteristics,
biocompatibility,
are
also
discussed.
Medicine in Novel Technology and Devices,
Journal Year:
2024,
Volume and Issue:
22, P. 100291 - 100291
Published: March 11, 2024
Mg
alloys
have
attractive
properties,
including
biocompatibility,
biodegradability,
and
ideal
mechanical
properties.
Moreover,
are
regarded
as
one
of
the
promising
candidates
for
manufacturing
ureteral
stents.
This
study
proposed
a
multi-objective
optimization
method
based
on
Kriging
surrogate
model,
NSGA-Ⅲ,
finite
element
analysis
to
improve
degradation
performance
alloy
The
model
stents
has
been
established
compare
under
different
parameters.
Latin
hypercube
sampling
was
adopted
generate
train
sample
points
in
design
space.
Meanwhile,
constructed
between
strut
parameters
stent
behavior.
NSGA-Ⅲ
utilized
determine
optimal
solution
global
optimized
achieved
5.52×
uniformity
(M),
10×
time
(DT),
4×
work
(FT).
errors
calculation
results
were
less
than
6%.
better
performance.
behavior
dependent
effective
problems.
Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 11, 2024
Magnesium
is
an
essential
mineral
with
pivotal
roles
in
various
physiological
processes,
including
enzyme
function,
neuromuscular
regulation,
and
cardiovascular
health.
Magnesium's
importance
critically
ill
pediatric
patients
magnified
due
to
its
involvement
maintaining
cellular
homeostasis
potential
therapeutic
benefits.
This
review
comprehensively
analyzes
magnesium's
role
critical
care
pediatrics,
focusing
on
mechanisms,
clinical
impact,
strategies.
functions
energy
production,
protein
synthesis,
electrolyte
balance
underscore
significance
illness,
where
imbalances
can
lead
severe
complications
such
as
arrhythmias,
disturbances,
respiratory
issues.
The
examines
the
consequences
of
magnesium
deficiency,
impact
body
systems
exacerbation
conditions.
It
also
explores
strategies
optimize
patient
care,
supplementation
practices,
dosing
considerations,
monitoring
protocols.
By
summarizing
recent
research
guidelines,
this
aims
enhance
understanding
provide
evidence-based
recommendations
for
management.
insights
provided
are
intended
guide
clinicians
integrating
therapy
into
ultimately
improving
outcomes
advancing
management
patients.
