Exploring the role of gut microbiota in antibiotic resistance and prevention DOI Creative Commons

Devyani S. Dongre,

Ujjayni Saha, Sunil D. Saroj

et al.

Annals of Medicine, Journal Year: 2025, Volume and Issue: 57(1)

Published: March 17, 2025

Background/Introduction Antimicrobial resistance (AMR) and the evolution of multiple drug-resistant (MDR) bacteria is grave public health concern. To combat pandemic AMR, it necessary to focus on novel alternatives for drug development. Within host, interaction pathogen with microbiome plays a pivotal role in determining outcome pathogenesis. Therefore, microbiome-pathogen one potential targets be explored antimicrobials.

Language: Английский

Revolutionizing Drug Delivery: The Impact of Advanced Materials Science and Technology on Precision Medicine DOI Creative Commons
Mohamed El‐Tanani, Shakta Mani Satyam, Syed Arman Rabbani

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(3), P. 375 - 375

Published: March 15, 2025

Recent progress in material science has led to the development of new drug delivery systems that go beyond conventional approaches and offer greater accuracy convenience application therapeutic agents. This review discusses evolutionary role nanocarriers, hydrogels, bioresponsive polymers enhanced release, target accuracy, bioavailability. Oncology, chronic disease management, vaccine are some applications explored this paper show how these materials improve results, counteract multidrug resistance, allow for sustained localized treatments. The also translational barriers bringing advanced into clinical setting, which include issues biocompatibility, scalability, regulatory approval. Methods overcome challenges surface modifications reduce immunogenicity, scalable production methods such as microfluidics, harmonization systems. In addition, convergence artificial intelligence (AI) machine learning (ML) is opening frontiers personalized medicine. These technologies predictive modeling real-time adjustments optimize needs individual patients. use can be applied rare underserved diseases; thus, strategies gene therapy, orphan drugs development, global distribution may hopes millions

Language: Английский

Citations

1

Exploring the role of gut microbiota in antibiotic resistance and prevention DOI Creative Commons

Devyani S. Dongre,

Ujjayni Saha, Sunil D. Saroj

et al.

Annals of Medicine, Journal Year: 2025, Volume and Issue: 57(1)

Published: March 17, 2025

Background/Introduction Antimicrobial resistance (AMR) and the evolution of multiple drug-resistant (MDR) bacteria is grave public health concern. To combat pandemic AMR, it necessary to focus on novel alternatives for drug development. Within host, interaction pathogen with microbiome plays a pivotal role in determining outcome pathogenesis. Therefore, microbiome-pathogen one potential targets be explored antimicrobials.

Language: Английский

Citations

0