Journal of Materials Chemistry B,
Journal Year:
2024,
Volume and Issue:
12(12), P. 2950 - 2984
Published: Jan. 1, 2024
This
review
highlights
the
design
and
engineering
of
ZnO
based
0–3D
nano-architectures,
thin
films
coatings
with
tunable
characteristics
for
multifunctional
biomedical
applications.
Nanomaterials,
Journal Year:
2024,
Volume and Issue:
14(5), P. 397 - 397
Published: Feb. 21, 2024
The
wide
array
of
structures
and
characteristics
found
in
ZnO-based
nanostructures
offers
them
a
versatile
range
uses.
Over
the
past
decade,
significant
attention
has
been
drawn
to
possible
applications
these
materials
biomedical
field,
owing
their
distinctive
electronic,
optical,
catalytic,
antimicrobial
attributes,
alongside
exceptional
biocompatibility
surface
chemistry.
With
environmental
degradation
an
aging
population
contributing
escalating
healthcare
needs
costs,
particularly
developing
nations,
there's
growing
demand
for
more
effective
affordable
devices
with
innovative
functionalities.
This
review
delves
into
particular
essential
facets
different
synthetic
approaches
(chemical
green)
that
contribute
production
multifunctional
nano-ZnO
particles
applications.
Outlining
conjugation
ZnO
nanoparticles
highlights
enhancement
capacity
while
lowering
toxicity.
Additionally,
recent
progress
study
nano-biomaterials
tailored
purposes
is
explored,
including
biosensing,
bioimaging,
tissue
regeneration,
drug
delivery,
as
well
vaccines
immunotherapy.
final
section
focuses
on
particles'
toxicity
mechanism
special
emphasis
neurotoxic
potential,
primary
pathways,
providing
overall
up-to-date
development
future
perspectives
biomedicine
field.
International Journal of Nanomedicine,
Journal Year:
2024,
Volume and Issue:
Volume 19, P. 12889 - 12937
Published: Dec. 1, 2024
Abstract:
Over
the
last
decade,
biomedical
nanomaterials
have
garnered
significant
attention
due
to
their
remarkable
biological
properties
and
diverse
applications
in
biomedicine.
Metal
oxide
nanoparticles
(NPs)
are
particularly
notable
for
wide
range
of
medicinal
uses,
including
antibacterial,
anticancer,
biosensing,
cell
imaging,
drug/gene
delivery.
Among
these,
zinc
(ZnO)
NPs
stand
out
versatility
effectiveness.
Recently,
ZnO
become
a
primary
material
various
sectors,
such
as
pharmaceutical,
cosmetic,
antimicrobials,
construction,
textile,
automotive
industries.
can
generate
reactive
oxygen
species
induce
cellular
apoptosis,
thus
underpinning
potent
anticancer
antibacterial
properties.
To
meet
growing
demand,
numerous
synthetic
approaches
been
developed
produce
NPs.
However,
traditional
manufacturing
processes
often
involve
economic
environmental
costs,
prompting
search
more
sustainable
alternatives.
Intriguingly,
synthesis
methods
utilizing
plants,
plant
extracts,
or
microorganisms
emerged
ideal
producing
These
green
production
techniques
offer
medicinal,
economic,
environmental,
health
benefits.
This
review
highlights
latest
advancements
applications,
showcasing
potential
revolutionize
field
with
eco-friendly
cost-effective
solutions.
Keywords:
antimicrobial,
antioxidant,
synthesis,
nanomedicine,
nanoparticle,
Chemistry Africa,
Journal Year:
2024,
Volume and Issue:
7(4), P. 1963 - 1980
Published: Jan. 29, 2024
Abstract
Nowadays,
metal
oxide
nanoparticles
(MO
NPs)
are
powerful
tools
for
biological
applications
due
to
their
distinctive
features.
Moreover,
the
efficacy
of
multimetallic
NPs
is
more
fascinating
because
structural
modifications
and
synergistic
effects.
This
study
utilized
one-pot
green
route
fabricate
trimetallic
ZnO-MgO-CuO
(ZMC)
employing
a
greener
reducing
agent
from
Artemisia
abyssinica
leaf
extract
(AALE).
The
crystal
structure,
size,
compositions,
shapes,
external
topology
ZMC
were
characterized
by
Fourier
transform
infrared
(FTIR)
,
UV–Visible
(UV–vis),
X-ray
diffraction
(XRD)
scanning
electron
microscopy
(SEM),
energy-dispersive
(EDX)
transmission
combined
with
selected
area
(TEM/HRTEM-SAED).
outcomes
suggested
that
bio-prepared
highly
crystalline
have
hexagonal
structures
lattice
monoclinic
symmetry
spherical
morphology
average
particle
sizes
14.67
15.13
nm,
respectively
.
Using
MTT
assay,
demonstrated
high
inhibition
percentage
(94.37
±
0.14
at
250
mg/mL)
an
IC
50
value
24.83
mg/mL
MCF-7
cell
lines.
in-vitro
antibacterial
potential
has
been
evaluated
against
four
bacterial
(Gram-positive
Gram-negative)
strains
highest
zone
(35
0.03
mm
)
S.
aureus
strain
lowest
(31
0.11
E.
coli
strain.
also
shown
strong
molecular
binding
interactions
amino
acids
estrogen
receptor
(ERα),
energies
−
9.85,
12.31,
6.04
kcal/mole,
respectively.
Graphical
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Nov. 30, 2024
Green
synthesis
using
plant
extracts
such
as
Ocimum
basilicum
L.
(OBL)
seed
has
attracted
attention
due
to
its
sustainable
and
environmentally
friendly
nature.
In
this
study,
ZnO-MgO-Mn2O3
nanocomposites
were
synthesized
OBL
extract
at
two
different
calcination
temperatures
of
500
°C
600
°C,
evaluated
in
terms
photocatalytic
application
cytotoxicity.
Phytochemicals
seeds
act
reducing
masking
agents
the
production
route,
which
leads
formation
nanomaterials
with
unique
properties.
Characterization
techniques,
including
XRD,
FE-SEM,
DRS
used
analyze
structural,
morphological,
optical
features
nanocomposite.
XRD
results
confirmed
increasing
crystal
size
from
~
32
nm
(500
°C)
84
(600
°C).
Also,
FE-SEM
images
showed
irregularly
shaped
EDX
spectra
samples
presence
zinc,
magnesium,
manganese,
oxygen
elements.
The
behavior
nanocomposite
cacined
was
investigated
for
organic
pollutants.
Removal
percentages
97%
Eriochrome
Black
T
dye
(pH
=
10
90
min),
99%
methylene
blue
60
89%
methyl
orange
105
86.9%
Rhodamine
B
3
min)
obtained.
Moreover,
cytotoxicity
on
4T1
cell
line
investgate
effect
biological
systems,
IC50
value
obtained
around
323
µg/mL.
ACS Omega,
Journal Year:
2023,
Volume and Issue:
8(44), P. 41039 - 41053
Published: Oct. 24, 2023
Currently,
plant
extract-mediated
synthesized
metal
oxide
nanoparticles
(MO
NPs)
have
played
a
substantial
role
in
biological
applications.
Hence,
this
study
focused
on
the
eco-benign
one-pot
synthesis
of
bimetallic
ZnO–CuO
(ZC
using
leaf
extract
Artemisia
abyssinica
(LEAA)
and
evaluations
their
anticancer,
antioxidant,
molecular
binding
efficacy.
The
optical
absorption
peak
at
380
nm
from
UV–visible
(UV–vis)
analysis
revealed
formation
ZC
NPs.
X-ray
diffraction
(XRD)
results
fabrication
mixed-phase
crystals
with
hexagonal
monoclinic
structures
NPs
an
average
crystallite
size
14
nm.
Moreover,
biosynthesis
spherical
morphology
particle
13.09
was
confirmed
by
scanning
electron
microscopy
(SEM),
energy-dispersive
(EDX),
transmission
(TEM)
results.
Fourier
transform
infrared
(FTIR)
thermogravimetric
(TGA/DTA)
spectroscopy
involvement
functional
groups
LEAA
during
exhibited
ferric
ion
reducing
power
(FRAP)
absorbance
1.826
±
0.00
200
μg/mL
DPPH
(2,2-diphenyl-1-picryl-hydrazyl-hydrate)
radical
scavenging
activity
95.71
0.02%
IC50
value
3.28
μg/mL.
had
shown
promising
vitro
anticancer
89.20
0.038
500
33.12
against
breast
cancer
(MCF-7)
cell
lines.
Likewise,
strong
affinity
(−8.50
kcal/mol)
estrogen
receptor
α
(ERα)
docking
simulations.
These
findings
suggested
that
biosynthesized
could
be
used
as
antioxidant
drug
candidates,
particularly
for
ailments.
However,
vivo
cytotoxicity
test
will
recommended
to
ensure
further
use
