Efficacy and Molecular Mechanisms of Nystatin Against Botrytis cinerea on Postharvest Table Grape

Foods, Journal Year: 2024, Volume and Issue: 13(22), P. 3624 - 3624

Published: Nov. 13, 2024

The primary cause of postharvest loss in table grape fruit is attributed to gray mold, which caused by Botrytis cinerea. present study confirmed the inhibitory effects nystatin on growth and development B. cinerea, led a remarkable reduction severity mold fruits. Furthermore, application disrupted membrane permeability causing increased cellular leakage cell death. In addition, transcriptome analysis showed that effectively modulated transcriptional profile genes involved ribosome mitochondrion biogenesis, as well oxidoreductase activity, thereby disrupting homeostasis organelles. Moreover, treatment down-regulated associated with trafficking, protein degradation ubiquitin–proteasome system, autophagy process, ultimately attenuating pathogenicity Collectively, can be considered viable agent for managing fruit.

Language: Английский

In vitro and in vivo synergistic inhibition of Malassezia furfur targeting cell membranes by Rosa rugosa Thunb. and Coptidis Rhizoma extracts

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 11, 2024

is a prevalent dermatophyte that significantly impairs patients' quality of life. This study aimed to evaluate the synergistic antifungal effects combined extracts from

Language: Английский