Evaluation of the Effects of Epicoccum nigrum on the Olive Fungal Pathogens Verticillium dahliae and Colletotrichum acutatum by 1H NMR-Based Metabolic Profiling

Journal of Fungi, Journal Year: 2025, Volume and Issue: 11(2), P. 129 - 129

Published: Feb. 8, 2025

Olive trees are a cornerstone of Mediterranean agriculture but face significant threats from diseases such as Verticillium wilt and olive anthracnose. These diseases, caused by dahliae Colletotrichum spp., respectively, result in economic losses degrade oil quality. While traditional chemical treatments present environmental risk, sustainable alternatives biological control agents (BCAs) gaining attention. Epicoccum nigrum, an antagonistic fungus, has shown potential BCA due to its production antimicrobial secondary metabolites. This study aimed observe whether E. nigrum ability against V. C. acutatum, elucidate the metabolic interactions between these fungi using NMR-based metabolomics. showed inhibitory effects on growth acutatum dahlia 44.97% 38.73% respectively. Metabolomic profiling revealed distinct biochemical responses dahliae, under mono- dual-culture. Multivariate statistical analysis highlighted shifts mycelia identified primary metabolites, glutamine, 4-aminobutyrate, phenylalanine that involved adaption for survival stress conditions presence competitor. The results could be important better understanding fungal metabolism, which is still poorly characterized. Further investigation needed, suggest serve BCA, offering more approach managing diseases.

Language: Английский

Experimental, Spectroscopic Analysis, DFT and Molecular Docking studies of Pyridine based biologically active anti-fungal drug derivative of para-benzoquinone and benzimidazole

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 142212 - 142212

Published: April 1, 2025

Language: Английский