Lion’s Mane Mushroom (Hericium erinaceus): A Neuroprotective Fungus with Antioxidant, Anti-Inflammatory, and Antimicrobial Potential—A Narrative Review DOI Open Access
Alex Graça Contato, Carlos Adam Conté-Júnior

Nutrients, Journal Year: 2025, Volume and Issue: 17(8), P. 1307 - 1307

Published: April 9, 2025

Hericium erinaceus, commonly known as lion’s mane mushroom, has gained increasing scientific interest due to its rich composition of bioactive compounds and diverse health-promoting properties. This narrative review provides a comprehensive overview the nutritional therapeutic potential H. with particular focus on anti-inflammatory, antioxidant, antimicrobial activities. A structured literature search was performed using databases such PubMed, Scopus, Science Direct, Web Science, Google Scholar. Studies published in last two decades focusing erinaceus’ were included. The chemical erinaceus includes polysaccharides, terpenoids (hericenones erinacines), phenolic compounds, which exhibit potent antioxidant effects by scavenging reactive oxygen species (ROS) inducing endogenous enzymes. Additionally, shows promising activity against bacterial fungal pathogens, applications combating antibiotic-resistant infections. mushroom’s capacity stimulate nerve growth factor (NGF) synthesis highlighted preventing managing neurodegenerative diseases, Alzheimer’s Parkinson’s. Advances biotechnological methods, including optimized cultivation techniques novel extraction may further enhance bioavailability pharmacological erinaceus. Despite findings, clinical validation remains limited. Future research should prioritize large-scale trials, standardization elucidation pharmacokinetics facilitate integration into evidence-based medicine. functional food, nutraceutical, adjunct agent highlights need for interdisciplinary collaboration between researchers, clinicians, regulatory bodies.

Language: Английский

Lion’s Mane Mushroom (Hericium erinaceus): A Neuroprotective Fungus with Antioxidant, Anti-Inflammatory, and Antimicrobial Potential—A Narrative Review DOI Open Access
Alex Graça Contato, Carlos Adam Conté-Júnior

Nutrients, Journal Year: 2025, Volume and Issue: 17(8), P. 1307 - 1307

Published: April 9, 2025

Hericium erinaceus, commonly known as lion’s mane mushroom, has gained increasing scientific interest due to its rich composition of bioactive compounds and diverse health-promoting properties. This narrative review provides a comprehensive overview the nutritional therapeutic potential H. with particular focus on anti-inflammatory, antioxidant, antimicrobial activities. A structured literature search was performed using databases such PubMed, Scopus, Science Direct, Web Science, Google Scholar. Studies published in last two decades focusing erinaceus’ were included. The chemical erinaceus includes polysaccharides, terpenoids (hericenones erinacines), phenolic compounds, which exhibit potent antioxidant effects by scavenging reactive oxygen species (ROS) inducing endogenous enzymes. Additionally, shows promising activity against bacterial fungal pathogens, applications combating antibiotic-resistant infections. mushroom’s capacity stimulate nerve growth factor (NGF) synthesis highlighted preventing managing neurodegenerative diseases, Alzheimer’s Parkinson’s. Advances biotechnological methods, including optimized cultivation techniques novel extraction may further enhance bioavailability pharmacological erinaceus. Despite findings, clinical validation remains limited. Future research should prioritize large-scale trials, standardization elucidation pharmacokinetics facilitate integration into evidence-based medicine. functional food, nutraceutical, adjunct agent highlights need for interdisciplinary collaboration between researchers, clinicians, regulatory bodies.

Language: Английский

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