Antioxidant Properties, Bioactive Compounds Contents, and Chemical Characterization of Two Wild Edible Mushroom Species from Morocco: Paralepista flaccida (Sowerby) Vizzini and Lepista nuda (Bull.) Cooke DOI Creative Commons
El Hadi Erbiai, Abdelfettah Maouni, Luís Pinto da Silva

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(3), P. 1123 - 1123

Published: Jan. 23, 2023

Mushrooms have been consumed for centuries and recently gained more popularity as an important source of nutritional pharmaceutical compounds. As part the valorization mushroom species in northern Morocco, current study aimed to investigate chemical compositions antioxidant properties two wild edible mushrooms, Paralepista flaccida Lepista nuda. Herein, bioactive compounds were determined using spectrophotometer methods, results showed that value total phenolic content (TPC) was found be higher P. (32.86 ± 0.52 mg) than L. nuda (25.52 0.56 mg gallic acid equivalents (GAEs)/mg dry methanolic extract (dme)). On other hand, flavonoid (TFC) greater flaccida, with values 19.02 0.80 10.34 0.60 (+)-catechin (CEs)/g dme, respectively. Moreover, ascorbic acid, tannin, carotenoids moderate, a non-significant difference between samples. High-performance liquid chromatography-mass spectrometry (HPLC-MS) analysis allowed identification quantification thirteen individual both nuda, whereas p-Hydroxybenzoic recognized major compound detected, 138.50 1.58 587.90 4.89 µg/g weight (dw), The gas (GC-MS) extracts revealed presence sixty-one sixty-six biomolecules, These biomolecules can mainly divided into four main groups, namely sugars, amino acids, fatty organic acids. glycerol (12.42%) mannitol (10.39%) observed while predominated by linolelaidic (21.13%) leucine (9.05%). strong property, evaluated DPPH (half maximal effective concentration (EC50) 1.18-0.98 mg/mL); β-carotene bleaching (EC50 0.22-0.39 reducing power methods 0.63-0.48 mg/mL), findings suggested mushrooms are potential sources various many which possess biological activities interesting foods pharmaceuticals industry.

Language: Английский

Valorization of Agro-Industrial Wastes and Residues through the Production of Bioactive Compounds by Macrofungi in Liquid State Cultures: Growing Circular Economy DOI Creative Commons
Sotirios Pilafidis, Panagiota Diamantopoulou, Konstantinos Gkatzionis

et al.

Applied Sciences, Journal Year: 2022, Volume and Issue: 12(22), P. 11426 - 11426

Published: Nov. 10, 2022

Vast quantities of side streams produced worldwide by the agricultural and food industry present an environmental challenge opportunity for waste upcycling in frame circular bioeconomy. Fungi are capable transforming lignocellulosic residues wastes into a variety added-value compounds with applications functional products, pharmaceuticals, chemicals, enzymes, proteins, emerging sector nutraceuticals. The liquid state culture fungi is efficient potentially scalable reproducible biotechnological tool that allows optimized production fungal metabolites. Particularly, utilization agro-industrial by-products, residues, as substrate macrofungi suggested attainable solution management these streams, contributing to climate change mitigation. This review presents recently published literature field cultures using different substrates, methods, factors affecting their growth metabolite production, well applications, focusing on natural valuable produced.

Language: Английский

Citations

32
Consequences of Arsenic Contamination on Plants and Mycoremediation-Mediated Arsenic Stress Tolerance for Sustainable Agriculture DOI Creative Commons
Anmol Gupta,

Priya Dubey,

Manoj Kumar

et al.

Plants, Journal Year: 2022, Volume and Issue: 11(23), P. 3220 - 3220

Published: Nov. 24, 2022

Arsenic contamination in water and soil is becoming a severe problem. It toxic to the environment human health. usually found small quantities rock, soil, air, which increase due natural anthropogenic activities. exposure leads several diseases such as vascular disease, including stroke, ischemic heart peripheral also increases risk of liver, lungs, kidneys, bladder tumors. oxidative stress that causes an imbalance redox system. Mycoremediation approaches can potentially reduce As level near contaminated sites are procuring popularity being eco-friendly cost-effective. Many fungi have specific metal-binding metallothionein proteins, used for immobilizing concentration from thereby removing accumulated crops. Some other mechanisms contamination, biosynthesis glutathione, cell surface precipitation, bioaugmentation, biostimulation, biosorption, bioaccumulation, biovolatilization, methylation, chelation As. Arsenic-resistant recombinant yeast significant potential better elimination areas. This review discusses relationship between exposure, stress, signaling pathways. We explain how overcome detrimental effects through mycoremediation, unraveling mechanism As-induced toxicity.

Language: Английский

Citations

31
Termite Mushrooms (Termitomyces), a Potential Source of Nutrients and Bioactive Compounds Exhibiting Human Health Benefits: A Review DOI Creative Commons
Soumitra Paloi, Jaturong Kumla,

Barsha Pratiher Paloi

et al.

Journal of Fungi, Journal Year: 2023, Volume and Issue: 9(1), P. 112 - 112

Published: Jan. 13, 2023

Termite mushrooms have been classified to the genus

Language: Английский

Citations

20
A review for cancer treatment with mushroom metabolites through targeting mitochondrial signaling pathway: In vitro and in vivo evaluations, clinical studies and future prospects for mycomedicine DOI Creative Commons
Sudeshna Nandi,

Rimpa Sikder,

Sylvie Rapior

et al.

Fitoterapia, Journal Year: 2023, Volume and Issue: 172, P. 105681 - 105681

Published: Sept. 23, 2023

Resistance to apoptosis stands as a roadblock the successful pharmacological execution of anticancer drug effect. A comprehensive insight into apoptotic signaling pathways and an understanding mechanisms resistance are crucial unveil new targets. At this juncture, researchers heading towards natural sources in particular, mushroom their potential drugs leads being reliable source potent bioactive compounds. Given continuous increase cancer cases, efficacy mushrooms has inevitably become fascinating object due higher safety margin multitarget. This review aimed collect summarize all available scientific data on with from extracts molecules order suggest attributes via mitochondrion -mediated intrinsic mechanism. Compiled revealed that components including polysaccharides, sterols terpenoids well prepared using 15 different solvents 53 species could be effective supportive treatment 20 various cancers. The underlying therapeutic studied explored through diverse complementary investigations: vitro assays, pre-clinical studies clinical randomized controlled trials. processes mainly involved were ROS production, mitochondrial membrane dysfunction, action caspase 3, 9, XIAP, cIAP, p53, Bax, Bcl-2. In summary, study provides facts pertaining beneficial effect active compounds against types is shedding light targeted pathways.

Language: Английский

Citations

20
Antioxidant Properties, Bioactive Compounds Contents, and Chemical Characterization of Two Wild Edible Mushroom Species from Morocco: Paralepista flaccida (Sowerby) Vizzini and Lepista nuda (Bull.) Cooke DOI Creative Commons
El Hadi Erbiai, Abdelfettah Maouni, Luís Pinto da Silva

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(3), P. 1123 - 1123

Published: Jan. 23, 2023

Mushrooms have been consumed for centuries and recently gained more popularity as an important source of nutritional pharmaceutical compounds. As part the valorization mushroom species in northern Morocco, current study aimed to investigate chemical compositions antioxidant properties two wild edible mushrooms, Paralepista flaccida Lepista nuda. Herein, bioactive compounds were determined using spectrophotometer methods, results showed that value total phenolic content (TPC) was found be higher P. (32.86 ± 0.52 mg) than L. nuda (25.52 0.56 mg gallic acid equivalents (GAEs)/mg dry methanolic extract (dme)). On other hand, flavonoid (TFC) greater flaccida, with values 19.02 0.80 10.34 0.60 (+)-catechin (CEs)/g dme, respectively. Moreover, ascorbic acid, tannin, carotenoids moderate, a non-significant difference between samples. High-performance liquid chromatography-mass spectrometry (HPLC-MS) analysis allowed identification quantification thirteen individual both nuda, whereas p-Hydroxybenzoic recognized major compound detected, 138.50 1.58 587.90 4.89 µg/g weight (dw), The gas (GC-MS) extracts revealed presence sixty-one sixty-six biomolecules, These biomolecules can mainly divided into four main groups, namely sugars, amino acids, fatty organic acids. glycerol (12.42%) mannitol (10.39%) observed while predominated by linolelaidic (21.13%) leucine (9.05%). strong property, evaluated DPPH (half maximal effective concentration (EC50) 1.18-0.98 mg/mL); β-carotene bleaching (EC50 0.22-0.39 reducing power methods 0.63-0.48 mg/mL), findings suggested mushrooms are potential sources various many which possess biological activities interesting foods pharmaceuticals industry.

Language: Английский

Citations

17