Uncovering the multifaceted properties of 6-pentyl-alpha-pyrone for control of plant pathogens
Frontiers in Plant Science,
Journal Year:
2024,
Volume and Issue:
15
Published: June 18, 2024
Some
volatile
organic
compounds
(VOCs)
produced
by
microorganisms
have
the
ability
to
inhibit
growth
and
development
of
plant
pathogens,
induce
activation
defenses,
promote
growth.
Among
them,
6-pentyl-alpha-pyrone
(6-PP),
a
ketone
Trichoderma
fungi,
has
emerged
as
focal
point
interest.
6-PP
been
isolated
characterized
from
thirteen
species
is
main
VOC
produced,
often
accounting
for
>50%
total
VOCs
emitted.
This
review
examines
abiotic
biotic
interactions
regulating
production
,
known
effects
on
pathogens
through
direct
indirect
mechanisms
including
induced
systemic
resistance.
While
there
are
many
reports
activity
against
vast
majority
laboratory
studies
involving
only
pathogen,
rather
than
glasshouse
or
field
host
in
system.
Biopesticides
based
may
well
provide
an
eco-friendly,
sustainable
management
tool
future
agricultural
production.
However,
before
this
can
happen,
challenges
demonstrating
disease
control
efficacy
field,
developing
efficient
delivery
systems,
determining
cost-effective
application
rates
must
be
overcome
6-PP’s
potential
pathogen
turned
into
reality.
Language: Английский
Light Spectrum Variations: Implications for Growth and Bioactive Compound Synthesis in Trigonella persica
Food Bioscience,
Journal Year:
2025,
Volume and Issue:
unknown, P. 106117 - 106117
Published: Feb. 1, 2025
Language: Английский
Linking a polyketide synthase gene cluster to 6-pentyl-alpha-pyrone, a Trichoderma metabolite with diverse bioactivities
Microbial Cell Factories,
Journal Year:
2025,
Volume and Issue:
24(1)
Published: April 21, 2025
Abstract
Background
Members
of
the
fungal
genus
Trichoderma
are
well-known
for
their
mycoparasitic
and
plant
protecting
activities,
rendering
them
important
biocontrol
agents.
One
most
significant
specialized
metabolites
(SMs)
produced
by
various
species
is
unsaturated
lactone
6-pentyl-alpha-pyrone
(6-PP).
Although
first
identified
more
than
50
years
ago
having
pronounced
antifungal
growth-promoting
properties,
biosynthetic
pathway
6-PP
still
remains
unresolved.
Results
Here,
we
demonstrate
that
biosynthesized
via
polyketide
biosynthesis
pathway.
We
Pks1,
an
iterative
type
I
synthase,
as
crucial
its
in
atroviride
,
a
recognized
prominent
production
abilities.
Phylogenetic
comparative
genomic
analyses
revealed
pks1
gene
part
cluster
conserved
those
known
to
produce
6-PP.
Deletion
caused
complete
loss
T.
reduction
activity
against
Botrytis
cinerea
Rhizoctonia
solani
.
Surprisingly,
absence
led
enhanced
lateral
root
formation
Arabidopsis
thaliana
during
interaction
with
Transcriptomic
analysis
co-regulation
adjacent
genes,
including
candidates
coding
C3H1-type
zinc
finger
protein
lytic
polysaccharide
monooxygenase,
suggesting
coordination
between
environmental
response
mechanisms.
Conclusion
Our
findings
establish
essential
providing
novel
insights
into
one
compounds
this
mycoparasite.
These
may
pave
way
development
improved
agents
application
potent
biopesticide
contributing
eco-friendly
sustainable
disease
management.
Language: Английский
Assessment of the chemical composition of buriti (Mauritia flexuosa Liliopsida) and cassava (Manihot esculenta Crantz) residues and their possible application in the bioproduction of coconut aroma (6 pentyl-α-pyrone)
Bioprocess and Biosystems Engineering,
Journal Year:
2024,
Volume and Issue:
47(10), P. 1633 - 1645
Published: July 6, 2024
Language: Английский
Bacuri and macaxeira waste: physical-chemical characterization and production of coconut bioaroma by solid-state fermentation
Revista Brasileira de Ciências Ambientais,
Journal Year:
2024,
Volume and Issue:
59
Published: Jan. 1, 2024
Agro-industrial
waste
is
considered
a
global
concern.
Many
of
these
residues
are
composed
considerable
amounts
lipids
and
starch
that
can
potentially
be
applied
in
bioprocesses,
as
the
case
with
from
bacuri
fruit
(Platonia
insignis
Mart.)
sweet
cassava
(Manihot
esculenta
Crantz),
practically
unexploited
bioproduction
aromas.
This
work
aimed
to
characterize
evaluate
coconut
aroma
6-pentyl-α-pyrone
solid-state
fermentation
using
fungi
Trichoderma
harzianum.
The
underwent
characterization.
Fermentations
were
conducted
under
different
humidification
conditions
(water,
nutrient
solution
without
additives,
solutions
glucose
or
sucrose)
for
nine
days.
Aromatic
compounds
extracted
by
solid-phase
microextraction
subsequently
quantified
gas
chromatography.
Analyses
residue
revealed
presence
some
nutritional
potential
fungus.
Still,
inhibition
halo
detected
proved
others,
such
resinous
derivatives
probably
responsible
lack
growth
bioproduction.
In
cassava,
not
inhibitors
had
low
production,
exceeding
7
ppm
(weight/weight).
Strategically,
mixed
and,
sucrose,
maximum
production
202.46±1.30
(w/w)
was
achieved,
proving
an
excellent
alternative.
Cassava
served
environment
easy
germination
fungal
spores
bacuri,
important
source
bioexploitation
nutrients,
especially
lipids,
resulting
increased
6-pentyl-α-pyrone.
Language: Английский
Light Regulates Secreted Metabolite Production and Antagonistic Activity in Trichoderma
Journal of Fungi,
Journal Year:
2024,
Volume and Issue:
11(1), P. 9 - 9
Published: Dec. 26, 2024
Secondary
metabolism
is
one
of
the
main
mechanisms
Trichoderma
uses
to
explore
and
colonize
new
niches,
6-pentyl-α-pyrone
(6-PP)
an
important
secondary
metabolite
in
this
process.
This
work
focused
on
standardizing
a
method
investigate
production
6-PP.
Ethanol
ethyl
acetate
were
both
effective
solvents
for
quantifying
6-PP
solution
had
limited
solubility
potato–dextrose–broth
media.
The
extraction
using
provided
rapid
efficient
process
recover
metabolite.
was
readily
produced
during
development
atroviride
growing
dark,
but
light
suppressed
its
production.
purified,
spectrum
by
nuclear
magnetic
resonance
mass
spectroscopy
identical
that
commercial
Light
also
induced
or
other
unidentified
metabolites
several
species
Trichoderma.
antagonistic
activity
T.
influenced
light,
as
suppression
plant
pathogens
greater
dark.
secreted
potato–dextrose–agar
differentially
regulated
indicating
with
against
pathogens.
has
influence
Trichoderma,
trait
key
relevance
selecting
strains
protection.
Language: Английский