Reactive Oxygen Species (ROS)-Mediated Antibacterial Oxidative Therapies: Available Methods to Generate ROS and a Novel Option Proposal

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(13), P. 7182 - 7182

Published: June 29, 2024

The increasing emergence of multidrug-resistant (MDR) pathogens causes difficult-to-treat infections with long-term hospitalizations and a high incidence death, thus representing global public health problem. To manage MDR bacteria bugs, new antimicrobial strategies are necessary, their introduction in practice is daily challenge for scientists the field. An extensively studied approach to treating consists inducing levels reactive oxygen species (ROS) by several methods. Although further clinical investigations mandatory on possible toxic effects ROS mammalian cells, evaluations extremely promising, topical use treat infected wounds ulcers, also presence biofilm, already clinically approved. Biochar (BC) carbonaceous material obtained pyrolysis different vegetable animal biomass feedstocks at 200–1000 °C limited O2. Recently, it has been demonstrated that BC’s capability removing organic inorganic xenobiotics mainly due persistent free radicals (PFRs), which can activate oxygen, H2O2, or persulfate absence transition metals electron transfer, generating ROS, turn degrade pollutants advanced oxidation processes (AOPs). In this context, antibacterial BC-containing PFRs have some authors against Escherichia coli Staphylococcus aureus, giving birth our idea BC-derived as novel method capable generation oxidative therapy. Here, general aspects concerning physiological pathological production regulation mechanism they could exert reviewed. methods currently adopted induce therapy discussed. Finally, first time, BC-related proposed source via AOPs.

Language: Английский

---

Reactive Oxygen Species (ROS)-Mediated Antibacterial Oxidative Therapies: Available Methods to Generate ROS and a Novel Option Proposal

Published: May 24, 2024

The increasing emergence of multidrug resistant (MDR) pathogens causes difficult-to-treat infections, with long-term hospitalizations and high incidence death, thus representing a global public health problem. To manage MDR bacteria bugs, new antimicrobial strategies are necessary, their introduction in practice is daily challenge for scientists the field. An extensively studied approach to treat infections consists inducing levels reactive oxygen species (ROS) by several methods. Although further clinical investigations mandatory on possible toxic effects ROS mammalian cells, evaluations extremely promising, topical use infected wounds ulcers, also presence biofilm, already clinically approved. Biochar (BC) carbonaceous material obtained pyrolysis different vegetable animal biomass feedstocks, at 200−1000 °C limited O2. Recently, it has been demonstrated that BC capability removing organic inorganic xenobiotics mainly due persistent free radicals (PFRs), which can activate oxygen, H2O2 or persulfate not transition metals electron transfer generating ROS, turn degrade pollutants advanced oxidation processes (AOPs). In this context, antibacterial containing PFRs have some authors against Escherichia coli Staphylococcus aureus, giving birth our idea BC-derived as novel method capable generation oxidative therapy. Here, general aspects concerning physiological pathological production regulation, mechanism they could exert reviewed. methods currently adopted induce therapy discussed. Finally, first time, BC-related proposed source via AOPs.

Language: Английский

---

Biochar-Derived Persistent Free Radicals: A Plethora of Environmental Applications in a Light and Shadows Scenario

Toxics, Journal Year: 2024, Volume and Issue: 12(4), P. 245 - 245

Published: March 27, 2024

Biochar (BC) is a carbonaceous material obtained by pyrolysis at 200–1000 °C in the limited presence of O2 from different vegetable and animal biomass feedstocks. BC has demonstrated great potential, mainly environmental applications, due to its high sorption ability persistent free radicals (PFRs) content. These characteristics enable carry out direct PFRs-mediated removal/degradation organic inorganic contaminants. The types PFRs that are possibly present depend on temperature kind pristine biomass. Since they can also cause ecological human damage, systematic evaluation behavior, risks, or management techniques BC-derived urgent. generally consist mixture carbon- oxygen-centered oxygenated carbon-centered radicals, depending pyrolytic conditions. Here, promote more productive beneficial use related stimulate further studies make them environmentally safer less hazardous humans, we have first reviewed most common methods used produce BC, main primary mechanisms which remove xenobiotics, as well reported for PFR formation BC. Secondly, discussed migration transformation PFRs; PFR-mediated application degrade pollutants, potential correlated possible strategies limit them.

Language: Английский

---

Pivotal Contribute of EPR‐Characterized Persistent Free Radicals in the Methylene Blue Removal by a Bamboo‐Based Biochar‐Packed Column Flow System

ChemCatChem, Journal Year: 2024, Volume and Issue: 16(21)

Published: July 25, 2024

Abstract Water remediation with biomass derivatives has attracted attention for its sustainable impact on the earth. Chemical procedures new adsorbent and active biomaterials must be implemented to remove organic pollutants more efficiently. Herein, we obtained a sustainable, environmentally, low‐cost biochar from bamboo Dendrocalamus giganteus (BBC, B400) by thermal treatment at 400 °C without physical chemical pre‐ post‐treatments. By electron paramagnetic resonance (EPR), determined quantification ageing of persistent free radicals (PFRs, 10 16 –10 19 spins/g) present in BBC over time. We demonstrated removal efficiency (R %) B400 against methylene blue (MB) aqueous solutions different concentrations H 2 O using novel B400‐packed column‐flow system. Results that MB via adsorption degradation strongly depended concentration carbon‐centred PFRs their stability Collectively, reduced full passivation proper treatments led remarkable loss efficiency, thus evidencing PFR‐mediated radical mechanism was predominant process. Experiments t‐butanol alcohol (TBA) aged as scavenger hydroxyl (⋅OH) have evidenced critical role generating reactive oxygens species (ROSs) solution, which catalysed oxidative MB. Kinetics studies carried out data vs time all experiments established profiles fresh were best described pseudo‐second order (PSO) kinetic model, suggesting mechanisms such transfer reactions PFRs‐mediated main contributors removal. On contrary, or insignificant content fitted models, describe absorption diffusional nor processes, lower efficiency. These findings will helpful potential pilot large‐scale wide range contaminants water.

Language: Английский

---

Valorization of Banana Peel Waste into Advanced Adsorbent Beads for the Removal of Emerging Pollutants from Wastewater

Materials, Journal Year: 2025, Volume and Issue: 18(5), P. 1084 - 1084

Published: Feb. 28, 2025

This study addresses environmental concerns by utilizing banana peel waste to develop innovative adsorbent materials for wastewater treatment, aligning with circular economy principles. Spherical beads were synthesized from sodium alginate mixed various peel-based materials, including pure powder (PBP), activated carbon (AC), and magnetic (MAC). These evaluated their efficiency in removing tetracycline (TC) hexavalent chromium (Cr(VI)) as model pollutants representing antibiotics heavy metals, respectively. Characterization of the revealed functional groups thermal stability conducive effective adsorption. Adsorption trials demonstrated that MAC achieved highest removal efficiencies, up 92% TC 79% Cr(VI). The adsorption process followed pseudo-second-order kinetics Langmuir isotherms. Remarkably, retained a significant capacity across reuse cycles, indicating regenerative potential. Comparisons other adsorbents highlight competitive performance these materials. results emphasize potential peel-derived cost-effective, sustainable solutions mitigating emerging water systems, promoting valorization protection. research demonstrates novel approach sequential without intermediate regeneration, showing can effectively remove both (VI) successive cycles. finding is particularly because it reveals presence previously adsorbed actually enhanced beads' second cycle, suggesting synergistic effect had not been reported literature. innovations contribute meaningfully treatment technologies, offering new insights into development multi-functional agricultural

Language: Английский

---

Guadua-bamboo laminar biochar production and use as a substrate for TiO ₂ deposition for photocatalytic activity against Escherichia coli 226 and Salmonella Typhimurium 211

International Wood Products Journal, Journal Year: 2025, Volume and Issue: unknown

Published: March 26, 2025

This study aimed to produce and characterise laminar biochar from Guadua angustifolia Kunth culms longitudinal cuts by TiO 2 sedimentation deposit with photocatalytic activity against bacteria; several ages height positions served cuts, fibre parenchyma compositions; containing the highest were transformed into modified pyrolysis; deposited evaluate Escherichia coli 226 Salmonella Typhimurium 211, percentages for MM, BM, TJ, TD, DM (ranging 59.50 63.78 %), among these, MD TD showed thermal stability, decomposition temperatures between 341.65 345.85 ºC. Elastic modulus in bending (E) these exceeded 3.06 GPa, indicating their mechanical strength. on exposed UV 253nm generated > 50 % inactivation of both bacteria after 30 min exposure (photocatalytic activity).

Language: Английский

---

Water hyacinth: Prospects for biochar-based, nano-enabled biofertilizer development

Heliyon, Journal Year: 2024, Volume and Issue: 10(17), P. e36966 - e36966

Published: Aug. 27, 2024

HighlightsThe main highlights of the review article are stated below.•To synthesize existing body literature related to utilization water hyacinth for nanobiochar and nanofertilizer production, identifying gaps in through advanced metadata search databases.•To summarize key research findings on environmental implications producing nanofertilizers derived from hyacinth.•To propose a possible mechanism action biochar-based nanofertilizer.•To identify government policies regulatory frameworks as well socioeconomic factors supporting management regulating its repurposing production.AbstractThe widespread proliferation (Eichhornia crassipes) aquatic ecosystems has raised significant ecological, environmental, concerns globally. These include reduced biodiversity, impeded transportation recreational activities, damage marine infrastructure, obstructions power generation dams irrigation systems. This critically evaluates challenges posed by (WH) investigates potential strategies converting biomass into value-added agricultural products, specifically nanonutrients-fortified, biochar-based, green fertilizer. The examines various methods functional fertilizer enhance plant nutrient uptake improve soil retention. slow or fast pyrolysis, gasification, laser ablation, arc discharge, chemical precipitation used biochar which can then be further nano-sized ball milling, top-down approach. Through these means, WH-derived economically viable, eco-friendly, sustainable, precision-driven, smart practices achieved. positive impacts this invasive also discussed, including prospects circular economy, job creation, input costs, increased productivity, sustainable management. Utilizing WH (or nano-enabled biochar) production offers promising strategy waste management, remediation, improvement waterway sustainability. To underscore importance work, analysis carried out reveals that an insignificant section have focused nano-fortification development. Therefore, aims expand knowledge upcycling non-food crop biomass, particularly using feedstock, provides crucial insights viable solution mitigating ecological species while enhancing productivity.Graphical abstract

Language: Английский

---

Resolving Coffee Waste and Water Pollution—A Study on KOH-Activated Coffee Grounds for Organophosphorus Xenobiotics Remediation

Journal of Xenobiotics, Journal Year: 2024, Volume and Issue: 14(3), P. 1238 - 1255

Published: Sept. 10, 2024

This study investigates using KOH-activated coffee grounds (KACGs) as an effective adsorbent for removing organophosphorus xenobiotics malathion and chlorpyrifos from water. Malathion chlorpyrifos, widely used pesticides, pose significant health risks due to their neurotoxic effects environmental persistence. Spent grounds, abundant biowaste production, are chemically activated with KOH enhance adsorptive capacity without thermal treatment. offers a sustainable solution management water remediation. Adsorption kinetics indicating rapid initial adsorption high affinity were observed, particularly chlorpyrifos. Isotherm studies confirmed favorable conditions, higher maximum capacities compared (15.0 ± 0.1 mg g

Language: Английский

---

Biochar for Ameliorating Soil Fertility and Microbial Diversity: From Production to Action of the Black Gold

iScience, Journal Year: 2024, Volume and Issue: 28(1), P. 111524 - 111524

Published: Dec. 2, 2024

Language: Английский

---