Risk factors and prevention of atrial fibrillation in the postoperative period after coronary artery bypass grafting: a literature review DOI Creative Commons
M. A. Kuzmichkina, В. С. Кавешников

Sechenov Medical Journal, Journal Year: 2024, Volume and Issue: 15(3), P. 4 - 14

Published: Nov. 1, 2024

The increasing volume of coronary artery bypass grafting inevitably contributes to a growing number postoperative complications. Atrial fibrillation (AF) develops in every second or third patient. This complication prolongs inpatient stays and increases costs the healthcare system. review presents data on risk factors for AF, as well proposed methods prevention treatment. research results indicate role type 2 diabetes mellitus, obesity, arterial hypertension; among laboratory parameters, mean platelet volume, red blood cell distribution width, C-reactive protein, erythrocyte sedimentation rate, monocyte/high-density lipoprotein cholesterol ratio are prognostic value. Drug non-drug treatment AF discussed. indicated presented works showed effectiveness, but had limitations.

Language: Английский

Association between triglyceride glucose index and adverse cardiovascular prognosis in patients with atrial fibrillation without diabetes: a retrospective cohort study DOI Creative Commons
Aobo Gong, Ying Cao, Zexi Li

et al.

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 25, 2025

Abstract Background Atrial fibrillation (AF) is the most prevalent arrhythmia encountered in clinical practice. Triglyceride glucose index (Tyg), a convenient evaluation variable for insulin resistance, has shown associations with adverse cardiovascular outcomes. However, studies on Tyg index’s predictive value prognosis patients AF without diabetes are lacking. Methods This retrospective study utilized electronic medical records to collect data hospitalized at West China Hospital from January June 2020. Participants were categorized into three groups based their levels. The primary outcome, major events, included cardiac death, stroke, and myocardial infarction. Kaplan–Meier curve, Cox proportional hazards regression model, restricted cubic spline employed explore relationship between performance of CHA2DS2-VASc model was evaluated after incorporating index. Results comprised 864 participants (mean age 67.69 years, 55.32% male, 57.52% paroxysmal AF). Patients high had significantly higher risk developing events (MACE) ( P < 0.001, hazard ratio: 2.05, 95% confidence interval:1.65–2.56). MACE middle group similar that low = 0.1) during 48-month follow-up period. focusing last 24 months revealed 0.015) group. analysis an S-shaped correlation MACE. combined showed improved net benefit. Conclusions A associated poorer diabetes. Integrating may enhance its performance, offering utility.

Language: Английский

Citations

1
Association of self-reported and accelerometer-based walking pace with incident cardiac arrhythmias: a prospective cohort study using UK Biobank DOI

Pei Qin,

Frederick K. Ho, Carlos Celis‐Morales

et al.

Heart, Journal Year: 2025, Volume and Issue: unknown, P. heartjnl - 325004

Published: April 15, 2025

Objectives Dedicated studies aimed at investigating the relationship between walking pace and arrhythmia are limited. This study assessed associations self-reported accelerometer measured incident cardiac arrhythmias, overall by subtype, explored metabolic inflammatory markers as possible mediators. Methods Self-reported average was available for 420 925 UK Biobank participants, time spent different paces 81 956 participants. Outcomes were arrhythmias: all, atrial fibrillation (AF), other (including bradyarrhythmias ventricular arrhythmias), arrhythmias. Cox proportional regression models used to investigate associations. Results Compared with slow pace, brisk associated significantly lower risks of all arrhythmias (hazard ratio (HR) 0.65, 95% confidence interval (CI) 0.62 0.68; HR 0.57, CI 0.54 0.60), AF (HR 0.62, 0.58 0.65; 0.54, 0.50 0.57) 0.69, 0.64 0.73; 0.61, 0.57 0.65). Overall, 36.0% association mediated via markers. The stronger in women, those aged <60 years, a body mass index <30, who had hypertension ≥2 long term conditions. Conclusions Average moderate decreased risk part pathways. Our findings suggest may be safe effective exercise reduce especially higher groups.

Language: Английский

Citations

0
Electro-metabolic coupling in atrial fibrillation: A deeper understanding of the metabolic driver DOI Open Access
Xinghua Qin,

Lingyan Jin,

Haoyu Gong

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2024, Volume and Issue: 180, P. 117536 - 117536

Published: Oct. 8, 2024

Language: Английский

Citations

2
Unveiling the Role of Endothelial Dysfunction: A Possible Key to Enhancing Catheter Ablation Success in Atrial Fibrillation DOI Open Access
George Ε. Zakynthinos, Vasiliki Tsolaki, Evangelos Oikonomou

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(4), P. 2317 - 2317

Published: Feb. 15, 2024

Atrial fibrillation, a prevalent type of arrhythmia, is increasingly contributing to the economic burden on healthcare systems. The development innovative treatments, notably catheter ablation, has demonstrated both impressive and promising outcomes. However, these treatments have not yet fully replaced pharmaceutical approaches, primarily due relatively high incidence atrial fibrillation recurrence post-procedure. Recent insights into endothelial dysfunction shed light its role in onset progression fibrillation. This emerging understanding suggests that function might significantly influence effectiveness ablation. Consequently, deeper exploration dynamics could potentially elevate status positioning it as primary treatment option for

Language: Английский

Citations

1
Impact of Body Mass Index in the Cardioverter Efficacy of Amiodarone in Persistent Atrial Fibrillation DOI Creative Commons

Carmen Ligero,

Pau Riera, Amine El Amrani

et al.

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(6), P. 693 - 693

Published: May 28, 2024

Background: Amiodarone is an anti-arrhythmic drug that has extensive tissue distribution and substantial storage in the fat tissue. Different studies have described some implications of body composition its pharmacokinetics pharmacodynamics. However, no clinical for efficacy. Methods: We studied 878 patients with persistent atrial fibrillation (AF) treated a regimen amiodarone referred to electrical cardioversion (ECV), included prospectively two Spanish registries. analyzed influence mass index (BMI), as well overweight obesity, efficacy achieving pharmacologic sinus rhythm (SR) before ECV. Results: A total 185 (21.1%) reverted SR Patients who had lower BMI than those did not revert (27.45 ± 4.36 kg/m2 vs. 29.11 4.09 kg/m2; p < 0.001). observed progressively probability reverting obese (normal weight 28.3%, 21.3%, obesity 13.1%; In logistic regression, (kg/m2) adjusted other related variables remained main factor inversely reversion (OR = 0.904 × kg/m2); CI 75% 0.864–0.946). Conclusions: negative relationship between increased SR, suggesting impact excess

Language: Английский

Citations

1
Biomarkers of fibrosis and inflammation and the risk of arrhythmia recurrence after elective electrical cardioversion in patients with atrial fibrillation and metabolic syndrome DOI Creative Commons
E. I. Barashkova, В. А. Ионин, Е. И. Баранова

et al.

Russian Journal of Cardiology, Journal Year: 2024, Volume and Issue: 29(5), P. 5847 - 5847

Published: April 2, 2024

Aim. To evaluate the effect of blood concentrations biomarkers inflammation and fibrosis, obesity parameters, parameters characterizing cardiac remodeling on risk recurrent atrial fibrillation (AF) within 6 months after elective electrical cardioversion (ECV) in patients with metabolic syndrome (MS). Materials methods. The study included AF MS (n=60) without (n=41), who underwent ECV. Prospective observation was carried out for months. Results. Arrhythmia recurrence ECV combination is higher than (34/60 9/41, p = 0.003). Among echocardiographic left volume index, epicardial adipose tissue thickness (EAT) are associated arrhythmia resumption AF. Blood galectin-3 (17.4 (12.8-19.6) 13.3 (5.1-14.9), p=0.0001), connective growth factor (CTGF) (163, 1 (134.1-232.2) 156.7 (104.7 - 189.1), p=0.002), differentiation 15 (GDF-15) (2343.9 (1206.1-3254.2 ) 986.1 (812.5-1775.5), p=0.0001) interleukin-6 (IL-6) (3.8 (2.3-7.3) 2.3 (1, 3-3.4), p=0001) arrhythmia. According to ROC analysis EAT, concentration IL-6 most predictive relapse MS; threshold values predictors were established: EAT more 6.1 mm, 2.8 pg/ml, 15.9 ng/ml. Conclusion. In combined MS, frequency maintaining sinus rhythm effective lower MS. Epicardial thickness, high

Language: Английский

Citations

0
Impairment in Right Ventricular-Pulmonary Arterial Coupling in Overweight and Obesity DOI Open Access
Athina Goliopoulou, Evangelos Oikonomou, Panagiotis Theofilis

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(12), P. 3389 - 3389

Published: June 10, 2024

Background: The association of obesity with right ventricular function and the interplay between heart pulmonary circulation is incompletely understood. We evaluate role as a determinant ventricular-pulmonary artery coupling (RVAC). Methods: retrospectively studied consecutive subjects without overt cardiovascular or disease. Subjects were stratified according to body mass index (BMI) normal weight, overweight, obese. A transthoracic echocardiographic study was used assess left functional structural parameters. RVAC assessed using ratio peak systolic velocity tricuspid annulus pressure (PASP). Results: total 145 enrolled diabetes mellitus incidence higher in There no difference global longitudinal strain PASP markers based on BMI. significantly lower presence (normal weight: 0.52 (0.19) cm·(sec·mmHg)−1 vs. overweight: 0.47 (0.16) obese: 0.43 (0.14) cm·(sec·mmHg)−1, p = 0.03), even after adjustment for confounders (β: −0.085, 95% confidence interval: −0.163, −0.009, 0.029). Conclusions: Our findings highlight relationship metabolic impairment RVAC, suggesting additional mechanisms failure development observed obese subjects.

Language: Английский

Citations

0
Cardiometabolic Risk Factors Related to Atrial Fibrillation and Metabolic Syndrome in the Pakistani Population DOI Creative Commons
Saira Rafaqat,

Saima Sharif,

Shagufta Naz

et al.

Medicina, Journal Year: 2024, Volume and Issue: 60(8), P. 1190 - 1190

Published: July 23, 2024

: This study aimed to examine the relationship between cardiometabolic risk factors and atrial fibrillation (AF) simultaneous presence of AF metabolic syndrome (MetS) in Pakistani population.

Language: Английский

Citations

0
Risk factors and prevention of atrial fibrillation in the postoperative period after coronary artery bypass grafting: a literature review DOI Creative Commons
M. A. Kuzmichkina, В. С. Кавешников

Sechenov Medical Journal, Journal Year: 2024, Volume and Issue: 15(3), P. 4 - 14

Published: Nov. 1, 2024

The increasing volume of coronary artery bypass grafting inevitably contributes to a growing number postoperative complications. Atrial fibrillation (AF) develops in every second or third patient. This complication prolongs inpatient stays and increases costs the healthcare system. review presents data on risk factors for AF, as well proposed methods prevention treatment. research results indicate role type 2 diabetes mellitus, obesity, arterial hypertension; among laboratory parameters, mean platelet volume, red blood cell distribution width, C-reactive protein, erythrocyte sedimentation rate, monocyte/high-density lipoprotein cholesterol ratio are prognostic value. Drug non-drug treatment AF discussed. indicated presented works showed effectiveness, but had limitations.

Language: Английский

Citations

0