Establishment of a prognostic model for pancreatic cancer based on mitochondrial metabolism related genes DOI Creative Commons

Qinwen Ba,

Xiong Wang,

Yanjun Lu

et al.

Discover Oncology, Journal Year: 2024, Volume and Issue: 15(1)

Published: Aug. 28, 2024

Pancreatic ductal adenocarcinoma (PAAD) is recognized as an exceptionally aggressive cancer that both highly lethal and unfavorable prognosis. The mitochondrial metabolism pathway intimately involved in oncogenesis tumor progression, however, much remains unknown this area. In study, the bioinformatic tools have been used to construct a prognostic model with metabolism-related genes (MMRGs) evaluate survival, immune status, mutation profile, drug sensitivity of PAAD patients.

Language: Английский

Nanotechnology-based drug delivery for breast cancer treatment: Current applications and future directions DOI Creative Commons
Md Abdus Samad, Iftikhar Ahmad, Torki A. Zughaibi

et al.

European Journal of Medicinal Chemistry Reports, Journal Year: 2025, Volume and Issue: unknown, P. 100268 - 100268

Published: April 1, 2025

Language: Английский

Citations

1
The Role of Genomics and Transcriptomics in Characterizing and Predicting Patient Response to Treatment in Triple Negative Breast Cancer (TNBC) DOI Creative Commons
F. Eduardo Corea-Dilbert,

Muhammad Zubair Afzal

Onco, Journal Year: 2025, Volume and Issue: 5(2), P. 18 - 18

Published: April 22, 2025

Breast cancer is a complex disease that one of the leading causes cancer-related mortality in women worldwide. Of subtypes breast cancer, most aggressive subtype triple negative (TNBC) due to its lack targets could be leveraged for treatment other subtypes. Current options both local and metastatic TNBC include radiation therapy, chemotherapy, surgery, targeted immunotherapy, which has been gaining popularity recent years. The role therapy somewhat limited paucity therapeutic personalized targets, and, heterogeneity disease, effectiveness these different modalities varies from patient patient. These unique elements are foundation medicine where genomics transcriptomics play critical increasing granularity patients’ treatment. purpose molecular tools identify biomarkers used further characterize each patient’s features predict how certain will affect survival prognosis. interplay between pathways involved response with progression aggressiveness phenomenon. In this review, we describe current state literature regard show promise clinical setting treatments such as radiation, surgery locally advanced TNBC.

Language: Английский

Citations

0
Establishment of a prognostic model for pancreatic cancer based on mitochondrial metabolism related genes DOI Creative Commons

Qinwen Ba,

Xiong Wang,

Yanjun Lu

et al.

Discover Oncology, Journal Year: 2024, Volume and Issue: 15(1)

Published: Aug. 28, 2024

Pancreatic ductal adenocarcinoma (PAAD) is recognized as an exceptionally aggressive cancer that both highly lethal and unfavorable prognosis. The mitochondrial metabolism pathway intimately involved in oncogenesis tumor progression, however, much remains unknown this area. In study, the bioinformatic tools have been used to construct a prognostic model with metabolism-related genes (MMRGs) evaluate survival, immune status, mutation profile, drug sensitivity of PAAD patients.

Language: Английский

Citations

0