Eurasian journal of applied biotechnology,
Journal Year:
2023,
Volume and Issue:
4, P. 55 - 63
Published: Dec. 28, 2023
Walnut
(Juglans
Regia
L.)
is
a
promising
plant
for
use
in
modern
medicine.
We
describe
the
reactions
of
Juglans
L.
microclones
exposed
to
cold
stress
vitro
at
cell
and
tissue
level.
Differences
water
content
tissues
anatomical
morphological
structure
stem
leaf
under
control
conditions
are
shown.
Significant
changes
parameters
various
tissues,
both
upward
downward,
tendency
values
decrease
were
revealed.
It
has
been
suggested
that
characteristics
organs
may
affect
phytochemical
biologically
active
substances
them,
valuable
pharmacy.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(21), P. 7328 - 7328
Published: Oct. 29, 2023
Extracts
rich
in
bioactive
compounds
from
natural
sources
have
received
great
interest
due
to
their
impact
on
human
health.
The
aim
of
this
research
is
focused
the
obtaining
and
characterization
several
extracts
Juglans
regia
L.
leaves
four
different
maturity
phases:
young
green
(YGL),
(GL),
mature
(MGL),
yellow
(YL),
using
solvents:
ethanol
(e),
water
(w),
or
water:ethanol
(1:1
(v/v)—m)
by
employing
methods:
magnetic
stirring
(MS),
ultrasound-assisted
(UA),
as
well
maceration
(M).
obtained
were
quantitatively
evaluated
through
spectrophotometric
Total
Polyphenol
Content
(TPC-Folin–Ciocalteu
assay)
Antioxidant
Capacity
(TEAC
assay).
Phytochemical
screening
means
Fourier-Transform
Ion–Cyclotron-Resonance
High-Resolution
Mass
Spectrometry
(FT-ICR-MS)
indicated
presence
40
belonging
phytochemical
classes:
phenolic
acids,
flavonoids,
flavones,
flavanones,
flavonones,
flavanols,
vitamins,
tereponoid,
steroid,
anthocyanidin,
other
compounds.
Based
TPC
TEAC
assays,
water-ethanol
mixture
was
found
be
proper
extraction
solvent,
with
best
results
being
for
YL
plant
material:
146.29
mg
GAE/g
DM
(TPC)
11.67
mM
TE/g
(TEAC).
This
type
extract
may
used
various
domains,
such
cosmetics
industry,
biomedical
field,
and/or
design
functional
foods,
relying
composition.
Anti-Cancer Agents in Medicinal Chemistry,
Journal Year:
2023,
Volume and Issue:
24(2), P. 96 - 116
Published: Nov. 17, 2023
The
efficacy
of
drugs
against
cancer
in
clinical
settings
may
be
limited
due
to
pharmacokinetic
issues,
side
effects
and
the
emergence
drug
resistance.
However,
a
class
anticancer
known
as
naphthalimides
have
proven
very
effective.
These
derivatives
demonstrated
effective
treating
different
types
cancers
exhibit
strong
DNA
binding
affinity.
properties
naphthalimide
allow
them
target
number
cell
lines.
Researchers
investigated
activity
numerous
derivatives,
such
heterocyclic
fused,
non-fused
substituted,
metal-substituted
carboxamide
derivatives.
Surprisingly,
some
demonstrate
greater
than
reference
norms,
cisplatin,
amonafide,
mitonafide
others
are
selective
many
primary
objective
this
research
is
comprehend
various
substitution
patterns
on
structure-activity
relationship
(SAR)
these
instances
which
they
enhance
or
reduce
biological
activity.
Current Catalysis,
Journal Year:
2024,
Volume and Issue:
13(1), P. 2 - 24
Published: Feb. 22, 2024
Abstract:
The
emergence
of
enantioselective
organocatalysis
as
a
potent
synthetic
chemistry
strate-gy
that
supports
metal-catalyzed
transformations
has
resulted
in
the
creation
novel
procedures
for
synthesis
various
chiral
molecules.
Organocatalysis
is
desirable
method
creating
com-plex
molecular
structures
due
to
its
many
benefits,
including
ease
use,
wide
availability
cat-alysts
and
low
toxicity.
Chemists
are
actively
exploring
methodologies
looking
into
applications
pyrrolidine-based
organocatalysts.
application
organocatalysts
spans
range
reaction
types,
highlighting
their
ability
participate
variety
catalytic
process-es.
current
study
offers
succinct
summary
principal
strategic
methods
producing
demonstrating
usefulness
organic
transformations.
Molecules,
Journal Year:
2024,
Volume and Issue:
29(22), P. 5310 - 5310
Published: Nov. 11, 2024
Oxidative
stress,
characterized
by
an
overproduction
of
reactive
oxygen
species
that
overwhelm
the
body's
physiological
defense
mechanisms,
is
a
key
factor
in
progression
parasitic
diseases
both
humans
and
animals.
Scabies,
highly
contagious
dermatological
condition
caused
mite
Eurasian journal of applied biotechnology,
Journal Year:
2023,
Volume and Issue:
4, P. 55 - 63
Published: Dec. 28, 2023
Walnut
(Juglans
Regia
L.)
is
a
promising
plant
for
use
in
modern
medicine.
We
describe
the
reactions
of
Juglans
L.
microclones
exposed
to
cold
stress
vitro
at
cell
and
tissue
level.
Differences
water
content
tissues
anatomical
morphological
structure
stem
leaf
under
control
conditions
are
shown.
Significant
changes
parameters
various
tissues,
both
upward
downward,
tendency
values
decrease
were
revealed.
It
has
been
suggested
that
characteristics
organs
may
affect
phytochemical
biologically
active
substances
them,
valuable
pharmacy.
