Monoclonal Antibodies and Hyperimmune Immunoglobulins in the Next Pandemic DOI
Massimo Franchini, Daniele Focosi

Current topics in microbiology and immunology, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Clinical Significance of Neutralizing Antibodies in COVID-19: Implications for Disease Prognosis DOI Creative Commons
Sudem Mahmutoğlu Çolak, Tuba İlgar, İlkay Bahçeci

et al.

Life, Journal Year: 2025, Volume and Issue: 15(3), P. 429 - 429

Published: March 8, 2025

The pathogenesis of COVID-19 highlights a complex relationship between disease severity and neutralizing antibodies (NAbs). We aimed to investigate the relationships among total NAb (tNAb) levels, presence potential neutralization (pNAbs), clinical outcomes patients. Patients aged ≥18 years diagnosed October 2021 September 2022 were grouped by symptom severity. Blood samples taken at two time points data on demographics, epidemiology, vaccination recorded. tNAbs pNAbs measured an enhanced chemiluminescence assay surrogate virus test, respectively. 68 52 patients analyzed. Twenty-six (38.2%) had severe infection. 28-day mortality rate was 16.2% (n = 11). tNAb levels in control blood (CBSs) significantly higher than those admission (ABSs) (p < 0.001). statistical analysis showed no pNAbs. Vaccinated ABSs CBSs 0.001 p 0.001, respectively). correlated with lower 0.026) milder course 0.041). Although these findings support correlation mortality, their seems be unrelated favorable outcomes.

Language: Английский

Citations

0

Fresh frozen plasma for neutralizing SARS-CoV-2: “An exploratory cross-sectional study and review of the state of the art” DOI

Marcial Delgado‐Fernández,

Juan Diego Ruíz-Mesa,

Almudena Rojas-González

et al.

Enfermedades Infecciosas y Microbiología Clínica, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0

Fresh frozen plasma for neutralizing SARS-CoV-2: “An exploratory cross-sectional study and review of the state of the art” DOI

Marcial Delgado‐Fernández,

Juan Diego Ruíz-Mesa,

Almudena Rojas-González

et al.

Enfermedades infecciosas y microbiologia clinica (English ed ), Journal Year: 2025, Volume and Issue: 43(5), P. 282 - 290

Published: May 1, 2025

Language: Английский

Citations

0

Towards the identification of the correct place for convalescent plasma among COVID-19 therapies DOI Open Access
Massimo Franchini, Daniele Focosi

Infectious Diseases, Journal Year: 2024, Volume and Issue: 56(6), P. 421 - 422

Published: March 29, 2024

Language: Английский

Citations

0

Monoclonal Antibodies and Hyperimmune Immunoglobulins in the Next Pandemic DOI
Massimo Franchini, Daniele Focosi

Current topics in microbiology and immunology, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Citations

0