Diabetes-Driven Retinal Neurodegeneration: Its Role in the Pathogenesis of Diabetic Retinopathy DOI Creative Commons
Ilaria Viganò, Silvia Galbiati, Emanuela Aragona

et al.

Biomedicines, Journal Year: 2025, Volume and Issue: 13(6), P. 1328 - 1328

Published: May 29, 2025

Diabetic retinopathy is a complication of diabetes characterized by an extremely low rate progression. It takes several years to move from the onset diabetes, both type 1 and 2, development retinal microaneurysms, then leading proliferative diabetic vision loss. The recent demonstration that microaneurysms are preceded and, possibly, caused subclinical neurodegeneration mainly affecting neurovascular unit has suggested, on one hand, possible existence previously unknown early neurodegenerative stage other, “neuroprotective” treatment could end up preventing microvascular stages. This review summarizes present situation in field focuses prevention retinopathy, which seems, for first time, be within reach.

Language: Английский

IGF-1 signaling pathway activation promotes axonal regeneration and repair: a mechanism study on catalpol-induced functional recovery after ischemic stroke DOI
Yan Liu, Dan Wu, Hua Hao

et al.

Journal of Ethnopharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 119808 - 119808

Published: April 1, 2025

Language: Английский

Citations

0
Diabetes-Driven Retinal Neurodegeneration: Its Role in the Pathogenesis of Diabetic Retinopathy DOI Creative Commons
Ilaria Viganò, Silvia Galbiati, Emanuela Aragona

et al.

Biomedicines, Journal Year: 2025, Volume and Issue: 13(6), P. 1328 - 1328

Published: May 29, 2025

Diabetic retinopathy is a complication of diabetes characterized by an extremely low rate progression. It takes several years to move from the onset diabetes, both type 1 and 2, development retinal microaneurysms, then leading proliferative diabetic vision loss. The recent demonstration that microaneurysms are preceded and, possibly, caused subclinical neurodegeneration mainly affecting neurovascular unit has suggested, on one hand, possible existence previously unknown early neurodegenerative stage other, “neuroprotective” treatment could end up preventing microvascular stages. This review summarizes present situation in field focuses prevention retinopathy, which seems, for first time, be within reach.

Language: Английский

Citations

0