Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(9), P. 2215 - 2215
Published: Aug. 27, 2023
Magnetite
nanoparticles
(MNPs)
have
been
intensively
studied
for
biomedical
applications,
especially
as
drug
delivery
systems
the
treatment
of
infections.
Additionally,
they
are
characterized
by
intrinsic
antimicrobial
properties
owing
to
their
capacity
disrupt
or
penetrate
microbial
cell
wall
and
induce
death.
However,
current
focus
has
shifted
towards
increasing
control
synthesis
reaction
ensure
more
uniform
nanoparticle
sizes
shapes.
In
this
context,
microfluidics
emerged
a
potential
candidate
method
controlled
nanoparticles.
Thus,
aim
present
study
was
obtain
series
antibiotic-loaded
MNPs
through
microfluidic
device.
The
structural
were
investigated
X-ray
diffraction
(XRD)
and,
selected
area
electron
(SAED),
morphology
evaluated
transmission
microscopy
(TEM)
high-resolution
TEM
(HR-TEM),
antibiotic
loading
assessed
Fourier-transform
infrared
spectroscopy
(FT-IR)
thermogravimetry
differential
scanning
calorimetry
(TG-DSC)
analyses,
and.
release
profiles
both
antibiotics
determined
UV-Vis
spectroscopy.
biocompatibility
MTT
assay
on
BJ
line,
while
against
S.
aureus,
P.
aeruginosa,
C.
albicans
strains.
Results
proved
considerable
uniformity
antibiotic-containing
nanoparticles,
good
biocompatibility,
promising
activity.
Therefore,
represents
step
forward
development
highly
effective
nanostructured
therapies.
Applied Water Science,
Journal Year:
2023,
Volume and Issue:
13(3)
Published: Feb. 9, 2023
Abstract
The
tannery
industry
inevitably
generates
toxic
and
catastrophic
wastewater,
which
results
in
a
huge
threat
to
public
health
water
resources.
Therefore,
this
work
aimed
synthesize
parthenium
hysterophorus-based
biochar–Fe
3
O
4
composite
for
removal
of
Cr(VI)
from
wastewater
under
full
factorial
experimental
designs
the
Box–Behnken,
was
analyzed
using
response
surface
methodology
four
independent
factors
pH
(3,
6,
9),
initial
concentrations
(40,
70,
100
mg/L),
contact
times
(30,
60,
90
min),
adsorbent
doses
(20,
mg/100
mL).
This
described
by
high
BET
area
237.4
m
2
/g,
XRD
prominent
peaks,
SEM
morphology
corroborate
FTIR
multifunctionalities
O–H
at
3296
cm
−1
,
vibration
ketone
C–OH
1240
C–O–C
1147
Fe–O
stretching
542
.
maximum
Cr(IV)
efficiency
91.8%
recorded
an
concentration
40
mg/L,
3,
dose
mL,
time
min,
whereas
minimum
17.3%
observed
20
mL
dose,
9,
30
min.
real
determined
be
85.13
mg/L
its
remediation
found
81.8%.
Langmuir’s
model
best
fit
with
data
R
0.99
q
max
400
mg/g,
showing
that
adsorption
process
homogenous
monolayer.
In
conclusion,
were
encouraging,
appears
potential
candidate
Cr
wastewater.
Polymers,
Journal Year:
2023,
Volume and Issue:
15(4), P. 971 - 971
Published: Feb. 16, 2023
Iron
oxide
nanoparticles
are
one
of
the
nanocarriers
that
suitable
for
novel
drug
delivery
systems
due
to
low
toxicity,
biocompatibility,
loading
capacity,
and
controlled
cancer
cells.
The
purpose
present
study
is
synthesis
coated
iron
sorafenib
(SFB)
its
effects
on
In
this
study,
Fe3O4
were
synthesized
by
co-precipitation
method,
then
was
loaded
onto
PEG@Fe3O4
nanoparticles.
FTIR
used
ensure
polyethylene
glycol
(PEG)
binding
nanoshells.
A
comparison
mean
size
crystalline
structure
performed
TEM,
DLS,
X-ray
diffraction
patterns.
Then,
cell
viability
obtained
MTT
assay
3T3
HepG2
lines.
According
FT-IR
results,
presence
O-H
C-H
bands
at
3427
cm-1
1420
peak
correlate
with
PEG
XRD
pattern
showed
cubic
spinel
trapped
magnetite
carrying
medium.
magnetic
properties
examined
a
vibrating-sample
magnetometer
(VSM).
IC50
values
72
h
treatment
carriers
Fe3O4@PEG
nanoparticle
line
15.78
μg/mL
(p
<
0.05).
This
using
them
in
process
could
be
beneficial
increasing
effect
Applied Sciences,
Journal Year:
2024,
Volume and Issue:
14(3), P. 1132 - 1132
Published: Jan. 29, 2024
Magnetite-based
nanoparticles
are
of
constant
interest
in
the
scientific
community
as
potential
systems
for
biomedical
applications.
Over
years,
ability
to
synthesize
diverse
based
on
iron
(II,
III)
oxide
has
been
mastered
maximize
their
effectiveness
targeted
delivery
active
substances
cancer
therapy.
The
present
review
explores
recent
literature
findings
that
detail
various
magnetic
nanosystems.
These
encompass
straightforward
designs
featuring
a
polymer
coating
core
and
more
intricate
matrices
delivering
chemotherapeutic
drugs.
This
paper
emphasizes
novel
synthetic
approaches
impact
efficacy
progress
anticancer
investigations,
specifically
targeting
particular
type.
research
also
delves
into
combinations
with
alternative
treatment
methods
diagnostic
approaches.
Additionally,
it
highlights
critical
aspect—the
interaction
cells—identifying
least
developed
aspect
current
these
systems.
