Materials Chemistry and Physics, Journal Year: 2024, Volume and Issue: unknown, P. 130304 - 130304
Published: Dec. 1, 2024
Language: Английский
Frontiers in Bioengineering and Biotechnology, Journal Year: 2023, Volume and Issue: 11
Published: Nov. 14, 2023
Dental implants have been extensively used in patients with defects or loss of dentition. However, the failure dental is still a critical problem clinic. Therefore, many methods designed to enhance osseointegration between and native bone. Herein, challenge healing process implant operation will be briefly introduced. Then, various surface modification emerging biomaterials tune properties summarized comprehensively.
Language: Английский
Citations
11
Journal of Dental Sciences, Journal Year: 2024, Volume and Issue: 19(3), P. 1426 - 1433
Published: April 18, 2024
Additive manufacturing (AM) technology, such as selective laser melting (SLM), has been used to fabricate medical devices of Ti-6wt.% Al-4wt.%V (Ti6Al4V) alloys in dentistry. Strontium (Sr) shown have the potential treat osteoporosis. The aim this study was investigate physicochemical and biological properties strontium-containing coatings on melted Ti6Al4V (SLM-Ti6Al4V) substrate. disk prepared by SLM method. were micro-arc oxidation (MAO) aqueous electrolytes. surface topography, chemical composition, phase MAO (SrMAO) performed scanning electron microscope (SEM), energy dispersive X-ray spectrometer (EDS), thin film diffraction (TF-XRD), respectively. apatite-forming ability conducted simulating body fluid (SBF), cell proliferation determined methylthiazoletetrazolium (MTT) assay. microstructure SLM-Ti6Al4V displays acicular α-phase organization. TF-XRD results indicated that SrMAO coating anatase, rutile, titanium. calcium, phosphorus, strontium detected EDS. Using SEM, morphology exhibited a uniform 3D porous structure. could induce bone-like apatite layer after immersion SBF, presented significantly higher than untreated specimens in-vitro experiments. All findings indicate formed surfaces exhibit benefit responses thereby are suitable for biomedical applications.
Language: Английский
Citations
3
Acta Biomaterialia, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
0
International Journal of Nanomedicine, Journal Year: 2025, Volume and Issue: Volume 20, P. 2205 - 2223
Published: Feb. 1, 2025
Osteoporosis, osteoarthritis, and fractures are bone-related disorders that have a huge impact on the quality of life healthcare systems worldwide. Traditional treatments, including bone grafts, their limitations, with grafts often being rejected by immune system infected, making new treatments necessary. Nanopillars based synthetic polymers been demonstrated to be promising tools for regeneration repair, showing emulate extracellular matrix composition, stimulate osteoblast activity induce osteointegration. In this review, nanopillars fabrication techniques, such as electrospinning, nanoimprint lithography self-assembly, also state art technology presented. Their role in modulating cellular responses via both physical biochemical means, enhance mineralization stabilize implants is discussed. Additionally, applications treating disorders, eg promotion fracture healing, augmentation dental or orthopedic implants, improvement tissue engineering discussed review. Using these focuses, each section examines opportunities challenges (eg optimizing processes, improving biocompatibility, investigating integration upcoming therapies like gene stem cell therapy) potential nanopillar technology. Finally, review points out requirement scalable long term biocompatibility studies multifunctional therapeutic strategies fully employ clinical scenarios. This seeks consolidate current knowledge polymer identify future directions use related through comprehensive
Language: Английский
Citations
0
Materials, Journal Year: 2023, Volume and Issue: 16(23), P. 7307 - 7307
Published: Nov. 24, 2023
The micro- and nanostructures, chemical composition, wettability of titanium surfaces are essential for dental implants’ osseointegration. Combining hydrophilicity nanostructure has been shown to improve the cell response shorten healing time. This study aimed investigate biological different levels nanotopographical modifications in aged non-aged surfaces. By plasma etching with fluorine gas 2,3,3,3-tetrafluoropropene (R1234yF), additional nanostructures were created on sample Furthermore, this treatment resulted sustained superhydrophilicity fluoride accumulation. We examined effect various nanostructuring processes aging using scanning electron microscopy, roughness analyses, measurement. In addition, all surface tested their effects fibroblast adhesion, proliferation, viability as well osteoblast differentiation. Our indicates that etching, 2,3,3,3-tetrafluoropropene, machined SLA neither favored nor had an adverse SAOS-2 line. Although fluorine-plasma-etched demonstrated improved viability, they did not lead early It is still unclear which properties mainly influence adhesion. Further physiochemical aspects, such electrostatic interaction tension, crucial be analyzed along roughness.
Language: Английский
Citations
5
Materials, Journal Year: 2024, Volume and Issue: 17(11), P. 2707 - 2707
Published: June 3, 2024
Surface treatment of implants facilitates osseointegration, with nanostructured surfaces exhibiting accelerated peri-implant bone regeneration. This study compared bone-to-implant contact (BIC) in hydroxyapatite (HA), sand-blasted and acid-etched (SLA), SLA calcium (Ca)-coated (XPEED®) surfaces. Seventy-five disk-shaped grade 4 Ti specimens divided into three groups were prepared, 16 per group tested New Zealand white rabbits. characterization was performed using X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), digital microscopy, a angle analyzer. Cell viability, proliferation, adhesion assessed MC3T3-E1 cells. Apatite formation evaluated modified simulated body fluid (m-SBF) incubation. After weeks healing, the outcomes reviewed BIC, area (BA), removal torque tests, histomorphometric evaluation. A microstructure analysis revealed irregular pores across all groups, XPEED Ca-coated surface. showed crystalline CaTiO3 layer on surfaces, evenly distributed Ca penetrating implants. All provided excellent environments for cell growth. The significantly higher density viability superior osseointegration than HA (p < 0.05); exhibited highest absorbance values. Thus, surface improved implant performance, biocompatibility, stability, osseointegration.
Language: Английский
Citations
1
Journal of Material Science and Technology, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 1, 2024
Language: Английский
Citations
1
Journal of Vacuum Science & Technology A Vacuum Surfaces and Films, Journal Year: 2023, Volume and Issue: 42(1)
Published: Dec. 22, 2023
After undergoing microarc oxidation, titanium alloys exhibit significantly enhanced biocompatibility, making them a subject of extensive research in the field biomedical applications. In this study, two-step oxidation method was used to prepare film layer with both macro-micro-nano tertiary structures on β-type alloy Ti-3Zr-2Sn-3Mo-25Nb (TLM), using phosphate-nitrate mixed electrolyte for first step and borate body second oxidation. The effects NaOH concentration, voltage, time size distribution macropores prepared by were investigated SEM, energy dispersive spectroscopy, XRD, metallurgical microscopy. wettability three-level structured its ability induce hydroxyapatite deposition evaluated through contact angle testing simulated fluid immersion experiments. overall findings indicate that process yielded diameters ranging from 200 400 μm, along micro-nanostructures measuring 2–15 μm 10–100 nm. increase concentration decreased macropores. increased macropores; voltage affected number membrane layers have excellent precipitation, indicating they possess good biocompatibility. This study provides reference medical development alloys.
Language: Английский
Citations
1
Materials Chemistry and Physics, Journal Year: 2024, Volume and Issue: unknown, P. 130304 - 130304
Published: Dec. 1, 2024
Language: Английский
Citations
0