Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 352, P. 123161 - 123161
Published: Dec. 18, 2024
Language: Английский
Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 352, P. 123161 - 123161
Published: Dec. 18, 2024
Language: Английский
Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 291, P. 117876 - 117876
Published: Feb. 1, 2025
Polylactic acid (PLA), as a bioplastic, is extensively utilized in bone tissue engineering for its biocompatibility, adaptability and affordability. However, the toxicological research of PLA still limited. The hydrolysis products induced inflammatory response which caused osteolysis mediated by oxidative damage through recruitment macrophages accumulation foreign body multinucleated giant cells, ultimately leading to failure regeneration. lack effective treatments highlights importance finding new therapies. This study systematically investigated potential molecular mechanisms PLA-induced employing network toxicology docking techniques. We first conducted toxicology-based assessment according structure PLA. result from integrating screening targets multiple databases identified 126 associated with osteolysis, then an interaction diagram was constructed. Gene ontology (GO)/KEGG enrichment analysis clarified that may cause via metabolic pathways cancer, well lipid atherosclerosis. Further STRING Cytoscape software screened 25 core including HSP90AA1, AKT1, SRC, STAT1 FYN. found enriched highly correlated covered 18 targets, supporting scientific hypothesis induces osteolysis. Moreover, results confirmed displayed strong binding ability formed stable binding. Taken together, this not only revealed biological mechanism but also provided evidence future prevention treatment inflammation.
Language: Английский
Citations
1iScience, Journal Year: 2024, Volume and Issue: 27(12), P. 111512 - 111512
Published: Dec. 1, 2024
Language: Английский
Citations
5Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 495, P. 153516 - 153516
Published: June 27, 2024
Language: Английский
Citations
4Composites Part B Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 112363 - 112363
Published: March 1, 2025
Language: Английский
Citations
0Fungal biology, Journal Year: 2025, Volume and Issue: unknown, P. 27 - 58
Published: Jan. 1, 2025
Language: Английский
Citations
0Advanced Engineering Materials, Journal Year: 2025, Volume and Issue: unknown
Published: March 3, 2025
Fused deposition modeling (FDM) is one of the most commonly used 3D printing techniques. FDM uses thermoplastics to manufacture final product. This review article provides a comprehensive overview use composite materials in printing. It explores various filament manufacturing methods, highlighting extrusion The main advantages using are discussed, then recycled filaments, their benefits, and difficulties possibilities related applications covered. Next, filaments aerospace, automotive, medical, electronics, prosthetics/orthotics explored. Finally, discusses current challenges suggests future directions for research.
Language: Английский
Citations
0Polymers, Journal Year: 2024, Volume and Issue: 16(14), P. 1981 - 1981
Published: July 11, 2024
Large amounts of agri-food waste are generated and discarded annually, but they have the potential to become highly profitable sources value-added compounds. Many these lignin-rich residues. Lignin, one most abundant biopolymers in nature, offers numerous possibilities as a raw material or renewable resource for production chemical products. This study aims explore revalorization agricultural by-products through extraction lignin subsequent depolymerization. Different residues were studied; river cane, rice husks, broccoli stems, wheat straw, olive stone investigated (all local wastes that typically incinerated). Traditional soda extraction, enhanced by ultrasound, is applied, comparing two different sonication methods. The yields from follows: cane (28.21%), husks (24.27%), (6.48%), straw (17.66%), stones (24.29%). Once extracted, depolymerization performed three methods: high-pressure reactor, ultrasound-assisted solvent depolymerization, microwave solvolysis. As result, new method has been developed patented, using first time graphene nanoplatelets (GNPs) promising carbonaceous catalyst, achieving 90.89% rate yielding several building blocks, including guaiacol, vanillin, ferulic acid, acetovanillone.
Language: Английский
Citations
2Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 352, P. 123161 - 123161
Published: Dec. 18, 2024
Language: Английский
Citations
0