Mitochondrial targeting and pH‐responsive release of dual‐functionalized mesoporous silica nanoparticles as pesticide carrier

Pest Management Science, Journal Year: 2025, Volume and Issue: unknown

Published: March 14, 2025

Abstract BACKGROUND Suitable nano‐pesticide carriers play a crucial role in enhancing the utilization efficiency of pesticides. Among these, mesoporous silica nanoparticles (MSNs) are most promising candidates for large‐scale and safe pesticide applications. RESULTS In present work, functionalized MSNs were demonstrated to be effective mitochondrial‐targeted delivering strobilurin fungicides (mitochondrial respiratory chain inhibitors). bi‐functionalized with carboxymethyl chitosan (CMC), which is pH‐responsive, (4‐carboxybutyl) triphenylphosphonium bromide (TPP), mitochondrial targeting. The loading capacity model pyraclostrobin (Py) on carrier reached 32%. vitro release experiments Py sustained performance carriers. Co‐localization mitochondria confirmed that targeting by nanoparticle carrier. Bioactivity assays showed superior antifungal activity Py@MSNs‐CMC‐TPP compared mono‐functionalized commercial suspension products. Moreover, even when concentrations Py@MSNs‐CMC increased 200% relative Py@MSNs‐CMC‐TPP, inhibition remained lower. This indicates reduced required amount while its efficiency. CONCLUSION With application pesticides, such as methoxyacrylates succinate dehydrogenase inhibitors, have significant potential emerge promising, environmentally friendly fungicide formulation. © 2025 Society Chemical Industry.

Language: Английский

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Challenges in current pest management Practices: Navigating problems and a way forward by integrating controlled release system approach

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 498, P. 154989 - 154989

Published: Sept. 5, 2024

Language: Английский

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Exploitation of functionalized green nanomaterials for plant disease management

Discover Nano, Journal Year: 2024, Volume and Issue: 19(1)

Published: July 18, 2024

Abstract A crucial determining factor in agricultural productivity is biotic stress. In addition, supply of quality food to the ever-increasing world’s population has raised demand tremendously. Therefore, enhanced crop only option mitigate these concerns. It ultimately demanded often and indiscriminate use synthetic agrochemicals such as chemical fertilizers, pesticides, insecticides, herbicides, etc. for management various stresses including a variety plant pathogens. However, chain biosphere are severely impacted due harmful their byproducts. Hence, it need hour search novel, effective ecofriendly approaches plants. Particularly, disease management, efforts being made take advantage newly emerged science i.e. nanotechnology creation inorganic nanoparticles (NPs) metallic, oxide, sulphide, through different routes application management. Among these, green nanomaterials which synthesized using environmentally friendly methods materials reported possess unique properties (such high surface area, adjustable size shape, specific functionalities) making them ideal candidates targeted control. Nanotechnology can stop losses by managing diseases from soil, plants, hydroponic systems. This review mainly focuses on biologically produced NPs treatment caused bacteria, viruses, fungi. The utilization synthesis intelligent pesticide biomolecule control delivery systems, considered its pursuit less hazardous, sustainable, methods.

Language: Английский

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A Rapid pH-Responsive Pyraclostrobin Delivery System with Enhanced Membrane Passing Property and Fungicidal Activity against Botrytis cinerea

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

As the second most important fungal pathogen, Botrytis cinerea (B. cinerea) poses a serious threat to crop yields and agricultural safety. Pyraclostrobin (PYR), broad-spectrum QoI fungicide, has been widely utilized since its launch in 2003. However, inhibitory effects of both PYR technical formulations on B. are not outstanding. Even at concentration 50 μg/mL, inhibition rates by remain below 85%. In this work, we prepared an acid-responsive Pickering emulsion encapsulating (PYR@BTIB-PE), which completely inhibited low concentrations (25 μg/mL) for first time. The PYR@BTIB-PE achieved fragmentation release within 4 min pH 5, was consistent with around cinerea. can rapidly when infected increased cinerea, thereby enhancing efficacy PYR. addition, released organic solvent from enhanced passing property membrane, facilitating more enter body improvement membrane rapid response worked together achieve complete Furthermore, flexible amphiphilic structures interaction leaf surface, suppressed droplet splashing, promoted spreading, reducing pesticide loss improving utilization rate pesticide. This study presents efficient strategy inhibiting is also expected be extended other antifungal preparations.

Language: Английский

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Preparation of a Self-Assembled Nanoantiviral Pesticide with Strong Adhesion Performance for Efficiency Control of Destructive Soybean Mosaic Virus

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 16, 2025

In this context, we reported for the first time design and development of a self-assembled nanoantiviral pesticide based on star polycation (SPc) broad-spectrum fungicide/antiviral agent seboctylamine field control Soybean mosaic virus (SMV), highly destructive plant in soybean crops. The SPc could self-assemble with through hydrogen bonds van der Waals forces, complexation reduced particle size to form spherical seboctylamine/SPc complex. addition, contact angle decreased, its retention increased aid SPc, indicating excellent wetting properties strong leaf surface adhesion performance. incorporation significantly inhibited viral accumulation plants enhanced efficacy against SMV, resulting improved agronomic traits. Overall, our study would contribute facilitating new strategy effective SMV soybeans.

Language: Английский

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Mesoporous Nanoparticles Applications in Agriculture

Published: Jan. 1, 2025

Language: Английский

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Agricultural nanotechnology for a safe and sustainable future: current status, challenges, and beyond

Journal of the Science of Food and Agriculture, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 25, 2024

Abstract Nanotechnology, which involves manipulating matter at the atomic and molecular scales to produce structures devices ranging from 1 100 nm, is increasingly being applied in agriculture. Nanoscale materials possess distinct optical, electrochemical, mechanical properties that enable smart, targeted delivery of pesticides, fertilizers, genetic plants, as well rapid sensing on‐site monitoring plant health, soil fertility, water quality a digital format. This review explores application nanotechnology agriculture, examining challenges benefits related all aspects crop production, with particular focus on regulatory issues. Key findings indicate can improve production reduce environmental footprint agriculture through precise input management. However, several critical issues need be addressed, including limited knowledge long‐term impacts associated agricultural ambiguity current regulations. underscores for further research elucidate its impact soil, water, human inform evidence‐based © 2024 The Author(s). Journal Science Food Agriculture published by John Wiley & Sons Ltd behalf Society Chemical Industry.

Language: Английский

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Fe-based metal-organic frameworks modified with carboxymethyl cellulose for targeted pesticide delivery and reducing biotoxicity

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 137285 - 137285

Published: Nov. 6, 2024

Language: Английский

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Phycogenic nanoparticles efficiently catalyse pesticide degradation through a novel metabolic pathway utilizing solar light

Chemosphere, Journal Year: 2024, Volume and Issue: 369, P. 143877 - 143877

Published: Dec. 1, 2024

Language: Английский

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