Nuclear Analysis, Journal Year: 2025, Volume and Issue: unknown, P. 100172 - 100172
Published: April 1, 2025
Language: Английский
Nanomaterials, Journal Year: 2025, Volume and Issue: 15(2), P. 117 - 117
Published: Jan. 15, 2025
Monte Carlo (MC) simulations have become important in advancing nanoparticle (NP)-based applications for cancer imaging and therapy. This review explores the critical role of MC modeling complex biological interactions, optimizing NP designs, enhancing precision therapeutic diagnostic strategies. Key findings highlight ability to predict bio-distribution, radiation dosimetry, treatment efficacy, providing a robust framework addressing stochastic nature systems. Despite their contributions, face challenges such as complexity, computational demands, scarcity reliable nanoscale data. However, emerging technologies, including hybrid approaches, high-performance computing, quantum simulation, are poised overcome these limitations. Furthermore, novel advancements FLASH radiotherapy, multifunctional NPs, patient-specific data integration expanding capabilities clinical relevance simulations. topical underscores transformative potential bridging fundamental research translation. By facilitating personalized nanomedicine streamlining regulatory trial processes, offer pathway toward more effective, tailored, accessible treatments. The continued evolution simulation techniques, driven by interdisciplinary collaboration technological innovation, ensures that will remain at forefront nanomedicine’s progress.
Language: Английский
Citations
2
Gels, Journal Year: 2025, Volume and Issue: 11(2), P. 81 - 81
Published: Jan. 21, 2025
Tissue-equivalent hydrogel dosimeters represent a class of tools that hold significant promise, particularly in the precise measurement three-dimensional dose distributions radiotherapy. Due to their physical properties closely resembling those human soft tissue, these effectively replicate energy transfer phenomena resulting from radiation interactions, such as atomic ionization and scattering by nuclei or electrons. Consequently, tissue-equivalent dosimeters, characterized linear properties, have been extensively applied medical physics, oncology, nuclear safety. Future advancements focusing on developing more stable, less toxic, normoxic, cost-effective could enable broader adoption. This review provides comprehensive overview key characteristics make tissue-equivalent, highlighting benefits, limitations, primary application areas. Additionally, it explores current polymeric gel technology discusses future directions aimed at optimizing performance accessibility for
Language: Английский
Citations
1
Encyclopedia, Journal Year: 2025, Volume and Issue: 5(1), P. 40 - 40
Published: March 20, 2025
In vivo dosimetry (IVD) is a vital component of modern radiotherapy, ensuring accurate and safe delivery radiation doses to patients by measuring dose parameters during treatment. This paper provides comprehensive overview IVD, covering its fundamental principles, historical development, the technologies used in clinical practice. Key techniques, including thermoluminescent dosimeters (TLDs), optically stimulated luminescent (OSLDs), diodes, metal-oxide-semiconductor field-effect transistors (MOSFETs), electronic portal imaging devices (EPIDs), are discussed, highlighting their applications, advantages, limitations. The role IVD external beam brachytherapy, pediatric treatments emphasized, particularly contributions quality assurance, treatment validation, error mitigation. Challenges such as measurement uncertainties, technical constraints, integration into workflows explored, along with potential solutions emerging innovations. also addresses future perspectives, advancements artificial intelligence, adaptive personalized systems. entry underscores critical enhancing precision reliability advocating for ongoing research technological development.
Language: Английский
Citations
0
Nuclear Analysis, Journal Year: 2025, Volume and Issue: unknown, P. 100172 - 100172
Published: April 1, 2025
Language: Английский
Citations
0