d-Galactose-induced accelerated aging model: an overview

Biogerontology, Journal Year: 2019, Volume and Issue: 20(6), P. 763 - 782

Published: Sept. 20, 2019

Language: Английский

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A review on the preparation of chitosan oligosaccharides and application to human health, animal husbandry and agricultural production

Carbohydrate Polymers, Journal Year: 2019, Volume and Issue: 220, P. 60 - 70

Published: May 15, 2019

Language: Английский

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Extracellular vesicles deposit PCNA to rejuvenate aged bone marrow–derived mesenchymal stem cells and slow age-related degeneration

Science Translational Medicine, Journal Year: 2021, Volume and Issue: 13(578)

Published: Jan. 27, 2021

Umbilical cord MSC–derived extracellular vesicles rejuvenate aged bone marrow MSCs and slow age-related degeneration in mice.

Language: Английский

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Photoactivatable senolysis with single-cell resolution delays aging

Nature Aging, Journal Year: 2023, Volume and Issue: 3(3), P. 297 - 312

Published: Feb. 2, 2023

Language: Английский

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Chitin and Chitosan Derivatives as Biomaterial Resources for Biological and Biomedical Applications

Molecules, Journal Year: 2020, Volume and Issue: 25(24), P. 5961 - 5961

Published: Dec. 16, 2020

Chitin is a long-chain polymer of N-acetyl-glucosamine, which regularly found in the exoskeleton arthropods including insects, shellfish and cell wall fungi. It has been known that chitin can be used for biological biomedical applications, especially as biomaterial tissue repairing, encapsulating drug delivery. However, postulated an inducer proinflammatory cytokines certain diseases asthma. Likewise, chitosan, N-acetyl-glucosamine d-glucosamine derived from deacetylation, chitosan oligosaccharide, short chain polymer, have their potential therapeutic effects, anti-inflammatory, antioxidant, antidiarrheal, anti-Alzheimer effects. This review summarizes utilization limitation chitin, oligosaccharide variety diseases. Furthermore, future direction research development applications discussed.

Language: Английский

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A Review: The Bioactivities and Pharmacological Applications of Phellinus linteus

Molecules, Journal Year: 2019, Volume and Issue: 24(10), P. 1888 - 1888

Published: May 16, 2019

Phellinus linteus is a popular medicinal mushroom that widely used in China, Korea, Japan, and other Asian countries. P. comprises various bioactive components, such as polysaccharides, triterpenoids, phenylpropanoids, furans, has proven to be an effective therapeutic agent traditional Chinese medicine for the treatment prevention of diseases. A number studies have reported possesses many biological activities useful pharmacological applications, including anticancer, anti-inflammatory, immunomodulatory, antioxidative, antifungal activities, well antidiabetic, hepatoprotective, neuroprotective effects. This review article briefly presents recent progress made understanding safety, prospects linteus, provides helpful references promising directions further linteus.

Language: Английский

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D-galactose-induced liver aging model: Its underlying mechanisms and potential therapeutic interventions

Experimental Gerontology, Journal Year: 2021, Volume and Issue: 150, P. 111372 - 111372

Published: April 24, 2021

Language: Английский

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Immune response, hematological traits, biochemical blood parameters, and histological status of laying hens influenced by dietary chitosan-oligosaccharides

Poultry Science, Journal Year: 2023, Volume and Issue: 102(9), P. 102834 - 102834

Published: June 3, 2023

This experiment aimed to examine the effect of chitosan-oligosaccharides (COS) supplementation in laying hens' diets affected their immune response, hematological characteristics, blood biochemical parameters, and histological status. At age 34 wk, 200 hens 20 cocks Mandarah chicken strain were allotted into four groups, each consisting 50 five cocks. The first group acted as a control group, fed on basal diet. second, third, fourth experimental groups received 0.1, 0.2, 0.5 g/kg COS addition base Birds at various dosages had significantly (P ˂ 0.05) increased serum concentration immunoglobulins, avian influenza, Newcastle disease antibodies compared with birds. Moreover, adding level 0.2 diet insignificantly enhanced response than rest treatment groups. Also, treated birds different levels improved parameters such red cells, white hemoglobin hematocrit group. all decreased cholesterol, triglycerides, Ca++ alanine aminotransferase concentrations In addition, chitosan-treated showed examination small intestine, isthmus, testis, notably given 0.1 other Cocks testicular tissues number diameter seminiferous tubules Morphological ileum villi number, height, crypt depth. It is possible conclude that physiological performance general health can be effectively by using chitosan or 2 response.

Language: Английский

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Exploring marine collagen: Sustainable sourcing, extraction methods, and cosmetic applications

South African Journal of Chemical Engineering, Journal Year: 2023, Volume and Issue: 47, P. 197 - 211

Published: Nov. 21, 2023

The predominant sources of collagen for cosmetic purposes were traditionally derived from bovine and porcine products, such as bones, tendons, connective tissues. However, these are gradually declining in popularity due to their restricted availability, religious constraints, disease-related concerns. Consequently, there is an urgent necessity explore alternative sustainable sources. Marine species offer a promising supply lower risk disease transmission, freedom restrictions, biocompatibility, molecular weight, production costs, simpler absorption by the human body. This review objective highlights potential marine resources (fishes, poriferans, mollusks, crustaceans, echinoderms, coelenterates) applications. A variety with different extraction techniques will be compared. study finds that fish by-products, particularly skins becoming very encouraging source contrasted other alternatives. They exhibit significant content, comprising up 61.26% dry weight under acid-soluble (ASC) method. Fish skin bone-derived mostly composed type I has been proven possess notable capabilities antioxidant, anti-aging, skin-whitening agent. Therefore, utilization key ingredient cosmetics promotes responsible sourcing, encourages eco-friendly practices, fosters circular economy making most underutilized materials.

Language: Английский

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Advances in the preparation and assessment of the biological activities of chitosan oligosaccharides with different structural characteristics

Food & Function, Journal Year: 2020, Volume and Issue: 12(3), P. 926 - 951

Published: Dec. 16, 2020

Chitosan oligosaccharides (COSs) are widely used biopolymers that have been studied in relation to a variety of abnormal biological activities the food and biomedical fields. Since different COS preparation technologies produce compounds with structural characteristics, it has not yet possible determine whether one or more chito-oligomers primarily responsible for bioactivity COSs. The inherent biocompatibility, mucosal adhesion nontoxic nature COSs well documented, as is fact they readily absorbed from intestinal tract, but their structure-activity relationship requires further investigation. This review summarizes methods preparation, research findings regard antioxidant, anti-inflammatory, anti-obesity, bacteriostatic antitumour activity characteristics. correlation between molecular structure bioactivities described, new insights into provided.

Language: Английский

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