Nano-Structures & Nano-Objects, Journal Year: 2024, Volume and Issue: 40, P. 101394 - 101394
Published: Nov. 1, 2024
Language: Английский
Marine Drugs, Journal Year: 2023, Volume and Issue: 21(2), P. 105 - 105
Published: Feb. 1, 2023
The aim of this study was to investigate the protective function and mechanism TCP3 (PKK), TCP6 (YEGGD) TCP9 (GPGLM) from skipjack tuna cardiac arterial bulbs on skin photoaging using UVB-irradiated HaCaT cell model. present results indicated that had significant cytoprotective effect cells (p < 0.001). Hoechst 33342 staining showed apoptosis UV-irradiated could be significantly reduced by treatment (GPGLM); JC-1 protect restoring mitochondrial membrane potential (MMP); Furthermore, down-regulate ratio Bax/Bcl-2 reduce expression level apoptosis-executing protein Caspase-3 decreasing Caspase-8 Caspase-9 0.05). action up-regulate levels Nrf2, NQO1 HO-1 0.05), which further increased activity downstream proteases (SOD, CAT GSH-Px), scavenged reactive oxygen species (ROS) decreased intracellular malondialdehyde (MDA). In addition, molecular docking (PKK) competitively inhibit Nrf2 binding site because they can occupy connection Kelch domain Keap1 protein. inferred non-competitive inhibition it not bind active summary, antioxidant peptides effectively damage used in development healthy cosmetic products treat diseases caused UV radiation.
Language: Английский
Citations
83
Marine Drugs, Journal Year: 2023, Volume and Issue: 21(10), P. 516 - 516
Published: Sept. 28, 2023
The objective of this study was to isolate and characterize collagen angiotensin-I-converting enzyme (ACE)-inhibitory (ACEi) peptides from the swim bladders monkfish (Lophius litulon). Therefore, acid-soluble (ASC-M) pepsin-soluble (PSC-M) with yields 4.27 ± 0.22% 9.54 0.51%, respectively, were extracted using acid methods. ASC-M PSC-M contained Gly (325.2 314.9 residues/1000 residues, respectively) as major amino acid, but they had low imino content (192.5 188.6 in comparison calf skins (CSC) (216.6 residues). sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) patterns ultraviolet (UV) absorption spectrums illustrated that mainly composed type I collagen. Subsequently, three ACEi isolated a hydrolysate prepared via double-enzyme system (alcalase + neutrase) identified SEGPK (MHP6), FDGPY (MHP7) SPGPW (MHP9), molecular weights 516.5, 597.6 542.6 Da, respectively. SEGPK, displayed remarkable anti-ACE activity, IC50 values 0.63, 0.94 0.71 mg/mL, Additionally, docking assay demonstrated affinities ACE -7.3, -10.9 -9.4 kcal/mol, activity due their connection active pockets and/or sites hydrogen bonding, hydrophobic interaction electrostatic force. Moreover, could protect HUVECs by controlling levels nitric oxide (NO) endothelin-1 (ET-1). work provides an effective means for preparation collagens novel bladders, peptides, including SPGPW, serve natural functional components development health care products control hypertension.
Language: Английский
Citations
72
South African Journal of Chemical Engineering, Journal Year: 2023, Volume and Issue: 47, P. 197 - 211
Published: Nov. 21, 2023
The predominant sources of collagen for cosmetic purposes were traditionally derived from bovine and porcine products, such as bones, tendons, connective tissues. However, these are gradually declining in popularity due to their restricted availability, religious constraints, disease-related concerns. Consequently, there is an urgent necessity explore alternative sustainable sources. Marine species offer a promising supply lower risk disease transmission, freedom restrictions, biocompatibility, molecular weight, production costs, simpler absorption by the human body. This review objective highlights potential marine resources (fishes, poriferans, mollusks, crustaceans, echinoderms, coelenterates) applications. A variety with different extraction techniques will be compared. study finds that fish by-products, particularly skins becoming very encouraging source contrasted other alternatives. They exhibit significant content, comprising up 61.26% dry weight under acid-soluble (ASC) method. Fish skin bone-derived mostly composed type I has been proven possess notable capabilities antioxidant, anti-aging, skin-whitening agent. Therefore, utilization key ingredient cosmetics promotes responsible sourcing, encourages eco-friendly practices, fosters circular economy making most underutilized materials.
Language: Английский
Citations
24
Marine Drugs, Journal Year: 2024, Volume and Issue: 22(2), P. 73 - 73
Published: Jan. 30, 2024
Marine lipids are recognized for their-health promoting features, mainly being the primary sources of omega-3 fatty acids, and therefore critical human nutrition in an age when global supply these nutrients is experiencing unprecedent pressure due to ever-increasing demand. The seafood industry originates a considerable yield co-products worldwide that, while already explored other purposes, remain mostly undervalued as sustainable healthy lipids, often low-value oil production. These especially appealing lipid since, besides well-known nutritional upside marine animal fat, which particularly rich polyunsaturated they also have interesting bioactive properties, may garner them further interest, not only food, but high-end applications. Besides added value that represent valuable sources, there obvious ecological reducing waste. In this sense, repurposing bioresources will contribute more use strain on heavily depleted stocks. Therefore, untapping potential aligns with both health environmental goals by guaranteeing additional eco-conscious practices.
Language: Английский
Citations
10
Marine Drugs, Journal Year: 2024, Volume and Issue: 22(4), P. 159 - 159
Published: March 30, 2024
Aging is closely associated with collagen degradation, impacting the structure and strength of muscles, joints, bones, skin. The continuous aging skin a natural process that influenced by extrinsic factors such as UV exposure, dietary patterns, smoking habits, cosmetic supplements. Supplements contain can act remedies help restore vitality youth to skin, helping combat aging. Notably, supplements enriched essential amino acids proline glycine, along marine fish collagen, have become popular for their safety effectiveness in mitigating process. To compile relevant literature on anti-aging applications search analysis peer-reviewed papers was conducted using PubMed, Cochrane Library, Web Science, Embase, covering publications from 1991 2024. From vitro vivo experiments, reviewed studies elucidate benefits emphasizing its role combating minimizing oxidative stress, photodamage, appearance wrinkles. Various bioactive peptides exhibit diverse properties, including free radical scavenging, apoptosis inhibition, lifespan extension various organisms, protective effects humans. Furthermore, topical application hyaluronic acid discussed mechanism increase production moisture, contributing supplementation. integration bio-tissue engineering also explored, highlighting proven utility healing bone regeneration applications. However, limitations scope exist. Thus, delving into these nuanced considerations, this review contributes comprehensive understanding potential challenges realm
Language: Английский
Citations
9
Waste Management Bulletin, Journal Year: 2024, Volume and Issue: 2(3), P. 84 - 100
Published: July 2, 2024
Seafood by-products from various organisms like fish, shellfish, squids, and bivalves are often thrown away as waste, even though they could be utilized in creating new types of valuable foods. Up to 75% the entire organism consists industrial processing wastes, which can lead a loss profit ecological sustainability if natural resources not recycled efficiently. Various fish parts byproducts, such heads, viscera, skin, bones, scales, exoskeletons, pens, ink, clam shells, categorized waste based on their weight percentages, vary depending species taxonomy. This review paper delves into extraction valorization strategies seafood by-products, with focus transforming resources. Marine provide bioactive substances collagen, peptides, polyunsaturated fatty acids, antioxidants, chitin, catalysts for biodiesel production. highlights utilization innovative techniques microwave- ultrasound-assisted well supercritical fluid subcritical water extract compounds section also discusses optimization processes enhance efficiency yield. Furthermore, explores potential applications across industries, emphasizing sustainable resource creation high-value products applied our current circular economy.
Language: Английский
Citations
8
International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 253, P. 126492 - 126492
Published: Aug. 25, 2023
Language: Английский
Citations
20
Marine Drugs, Journal Year: 2024, Volume and Issue: 22(5), P. 226 - 226
Published: May 17, 2024
Utilizing plant-based resources, particularly their by-products, aligns with sustainability principles and circular bioeconomy, contributing to environmental preservation. The therapeutic potential of plant extracts is garnering increasing interest, this study aimed demonstrate promising outcomes from an extract obtained underutilized waste. Chaetomorpha linum, invasive macroalga found in the Orbetello Lagoon, thrives eutrophic conditions, forming persistent mats covering approximately 400 hectares since 2005. biomass C. linum undergoes mechanical harvesting treated as waste, requiring significant human efforts economic resources—A critical concern for municipalities. Despite posing challenges local ecosystems, identified a natural source bioactive metabolites. Phytochemical characterization revealed lipids, amino acids, other compounds anti-inflammatory activity extract. In vitro assays LPS-stimulated RAW 264.7 TNF-α/IFN-γ-stimulated HaCaT cells showed inhibited reactive oxygen species (ROS), nitric oxide (NO), prostaglandin E2 (PGE2) productions, reduced inducible synthase (iNOS) cyclooxygenase-2 (COX-2) expressions via NF-κB nuclear translocation, cells. It also chemokines (TARC/CCL17, RANTES/CCL5, MCP-1/CCL2, IL-8) cytokine IL-1β production cells, suggesting candidate chronic diseases like atopic dermatitis. Finally, silico studies indicated palmitic acid contributor observed effect. This research not only uncovered untapped but laid foundation its integration into promoting sustainable practices, innovative applications across various industries.
Language: Английский
Citations
7
Cosmetics, Journal Year: 2024, Volume and Issue: 11(4), P. 112 - 112
Published: July 6, 2024
In a world increasingly focused on eco-conscious living, the cosmetic industry is actively adopting nanotechnology to transform plant and animal by-products into high-value beauty products. This comprehensive review explores innovative sustainable approaches for extracting utilizing bioactive compounds from these by-products. The application of nanocarrier systems highlighted their role in enhancing delivery efficacy safety ingredients skincare Consumer demand environmental concerns drive shift towards natural Traditional production often involves significant ecological impacts, prompting seek greener alternatives. addresses critical need solutions that align with global sustainability goals, particularly those outlined 2030 Agenda Sustainable Development. provides valuable insights current trends future directions cosmetics by focusing uniquely integrates practices industry. It details benefits using nanocarriers improve stability, bioavailability, derived waste. intersection high-tech methodologies offers novel perspective innovation. Future research should focus overcoming technical, regulatory, economic challenges scaling up applications. Investigations include development transparent supply chains, standardization methods characterizing nanoparticles, lifecycle assessments ensure safety. Additionally, fostering collaboration between scientific research, practices, consumer education vital advancing practices. contributes broader discourse presenting clear pathway integrating approaches. ensures products meet expectations promote stewardship circular economy, ultimately benefiting both skin planet.
Language: Английский
Citations
7
iScience, Journal Year: 2024, Volume and Issue: 27(12), P. 111339 - 111339
Published: Nov. 7, 2024
As the global population continues to grow, so does demand for longer, healthier lives and environmentally responsible choices. Consumers are increasingly drawn naturally sourced products with proven health wellbeing benefits. The marine environment presents a promising yet underexplored resource cosmetics industry, offering bioactive compounds potential safe biocompatible ingredients. This manuscript provides comprehensive overview of organisms production, highlighting marine-derived their applications in skin/hair/oral-care products, cosmeceuticals more. It also lays down critical safety considerations addresses methodologies sourcing compounds, including harvesting, biorefinery concept, use systems biology enhanced product development, relevant regulatory landscape. review is enriched by three case studies: design macroalgal skincare Iceland, establishment microalgal spin-off Italy, utilization proteins cosmeceutical applications.
Language: Английский
Citations
6