Editorial: Omics-based identification, characterization, and validation of marine bioactive peptides DOI Creative Commons
Tatiana V. Ovchinnikova, Qiong Shi

Frontiers in Marine Science, Journal Year: 2023, Volume and Issue: 10

Published: Nov. 17, 2023

EDITORIAL article Front. Mar. Sci., 17 November 2023Sec. Marine Biotechnology and Bioproducts Volume 10 - 2023 | https://doi.org/10.3389/fmars.2023.1323847

Language: Английский

An alternative source of medicines: pharmaceutical utilization of animal-derived metabolites DOI Creative Commons
Gülin Renda

Phytochemistry Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 3, 2025

Abstract Throughout history, various human civilizations have used raw materials obtained from the body parts, metabolic byproducts, or non-animal components of animals as medical resources for treatment numerous diseases and relief symptoms. Protein structures, including hormones enzymes, well animal-derived metabolites polysaccharides, lipids, vitamins, been development drugs. These chemicals include widely substances heparin, melatonin, collagen, glucosamine, chondroitin, bile acids, coenzyme Q10. Additionally, they such snake, spider, amphibian poisons, which are now undergoing therapeutic development. This review presents examples pharmaceutical that being drugs potential in drug research. Detailed descriptions chemical original sources effects these included. In general, production method was previously carried out by using animal organisms has replaced utilization recombinant technologies. The use a resource process is expected to remain an interesting topic further research this area expected. Nevertheless, it essential not disregard suggestions against utilizing production, particularly cases where alternative accessible.

Language: Английский

Citations

1

Nanohydroxyapatite/Peptide Composite Coatings on Pure Titanium Surfaces with Nanonetwork Structures Using Oyster Shells DOI Creative Commons

Kuan-Hsiang Hsieh,

Hsueh-Chuan Hsu, Yu‐Lin Kao

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(7), P. 577 - 577

Published: March 26, 2024

Titanium and its alloys are extensively applied in artificial tooth roots because of their excellent corrosion resistance, high specific strength, low elastic modulus. However, biological inertness, surface needs to be modified improve the osteointegration titanium implants. The preparation biologically active calcium–phosphorus coatings on an implant is one effective method for enhancing likelihood bone integration. In this study, osteoinductive peptides were extracted from oyster shells by using acetic acid. Two peptide-containing hydroxyapatite (HA) composite then prepared: coating was prepared hydrothermally synthesizing HA presence (HA/P/M), other immersing synthesized a peptide solution (HA/P/S). Characterization results indicated that containing shell-based successfully alkali-treated pure surfaces. HA/P/M HA/P/S found exhibit hydrophilicity. Protein adsorption tests confirmed had approximately 2.3 times higher concentration adsorbed proteins than coating.

Language: Английский

Citations

4

Advances in Biosensors for the Rapid Detection of Marine Biotoxins: Current Status and Future Perspectives DOI Creative Commons
Xiangwei Zhu,

Yufa Zhao,

Long Wu

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(4), P. 203 - 203

Published: April 19, 2024

Marine biotoxins (MBs), harmful metabolites of marine organisms, pose a significant threat to ecosystems and human health due their diverse composition widespread occurrence. Consequently, rapid efficient detection technology is crucial for maintaining ecosystem health. In recent years, has garnered considerable attention its pivotal role in identifying MBs, with advancements sensitivity, specificity, accuracy. These technologies offer attributes such as speed, high throughput, automation, thereby meeting requirements across various scenarios. This review provides an overview the classification risks associated MBs. It briefly outlines current research status biotoxin biosensors introduces fundamental principles, advantages, limitations optical, electrochemical, piezoelectric biosensors. Additionally, explores applications MBs presents forward-looking perspectives on development, which aims be comprehensive resource design implementation tailored effective MB detection.

Language: Английский

Citations

4

Hemolymph microbiota and immune effectors’ expressions driven by geographical rearing acclimation of the aquacultured Penaeus stylirostris DOI Creative Commons
Valérie Perez,

Viviane Boulo,

Julien de Lorgeril

et al.

Animal Microbiome, Journal Year: 2025, Volume and Issue: 7(1)

Published: Jan. 11, 2025

In holobiont, microbiota is known to play a central role on the health and immunity of its host. Then, understanding microbiota, dynamic according environmental conditions link would help react potential dysbiosis aquacultured species. While gut highly studied, in marine invertebrates hemolymph often set aside even if it remains an important actor homeostasis. Indeed, harbors factors involved animal homeostasis that interacts with immunity. Southwest Pacific, high economical valued shrimp Penaeus stylirostris reared two contrasted sites, New Caledonia (NC) French Polynesia (FP). We characterized active inhabiting shrimps while considering stability during seasons at one-month interval evidenced microbial variability between rearing sites. highlighted specific biomarkers along common core composed 6 ASVs. Putative functions were mostly associated bacterial competition, infections metabolism NC, they cell FP suggesting site discrimination. Differential relative expression immune effectors measured populations from NC FP, exhibited higher level compared FP. addition, differential was correlated based their geographical location. Our data suggest that, Pacific shrimps, both could have undergone immunostimulation as well adaptative divergence Further, identification proxies such biomarkers, be used guide future actions monitor thus preserve productions.

Language: Английский

Citations

0

Proteomic Diversity of the Sea Anemone Actinia fragacea: Comparative Analysis of Nematocyst Venom, Mucus, and Tissue-Specific Profiles DOI Creative Commons
Ricardo Barroso, Tomás Rodrigues, Alexandre Campos

et al.

Marine Drugs, Journal Year: 2025, Volume and Issue: 23(2), P. 79 - 79

Published: Feb. 11, 2025

Sea anemones (Actiniaria, Cnidaria) are promising targets for biomedical research, as they produce unique bioactive compounds, including toxins and antimicrobial peptides (AMPs). However, the diversity mechanisms underlying their chemical defenses remain poorly understood. In this study, we investigate proteomic profiles of unexplored sea anemone Actinia fragacea by analyzing its venom nematocyst extract, tissues, mucus secretion. A total 4011 different proteins were identified, clustered into 3383 protein groups. Among 83 putative detected, actinoporins, neurotoxins, phospholipase A2 uncovered, well two novel zinc metalloproteinases with specific domains (ShK) associated potassium channel inhibition. Common Gene Ontology (GO) terms related to immune responses, cell adhesion, protease inhibition, tissue regeneration. Furthermore, 1406 13,276 distinct identified predicted potential AMPs, a Aurelin-like AMP localized within nematocysts. This discovery highlights strengthens evidence cnidarian-exclusive Aurelin peptide family. Several other compounds distinctive defense functions also enzymes, pattern recognition (PRPs), neuropeptides. study provides first proteome map A. fragacea, offering critical foundation exploring valuable insights molecular complexity.

Language: Английский

Citations

0

Innovative Protein Sources from Freshwater and Marine Environments - A Comprehensive Review DOI Creative Commons
Nayara Pereira Lima, Giselle Maria Maciel,

Débora Fernandes Pinheiro

et al.

Measurement Food, Journal Year: 2025, Volume and Issue: unknown, P. 100215 - 100215

Published: Feb. 1, 2025

Language: Английский

Citations

0

Harnessing marine antimicrobial peptides for novel therapeutics: A deep dive into ocean-derived bioactives DOI
Kunal Agam Kanaujia,

Suraj Wagh,

Giriraj Pandey

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 307, P. 142158 - 142158

Published: March 17, 2025

Language: Английский

Citations

0

From Fins to Furs: Unlocking the therapeutic potential of animal-derived bioactives for wound care DOI Creative Commons

Hui Sin Lim,

Christopher J. Serpell, Satoshi Ogawa

et al.

Medicine in Drug Discovery, Journal Year: 2025, Volume and Issue: unknown, P. 100206 - 100206

Published: March 1, 2025

Language: Английский

Citations

0

Antimicrobial peptides in nematode secretions – Unveiling biotechnological opportunities for therapeutics and beyond DOI Creative Commons

E I Sutcliffe,

Allister Irvine, James Rooney

et al.

Biotechnology Advances, Journal Year: 2025, Volume and Issue: unknown, P. 108572 - 108572

Published: March 1, 2025

Language: Английский

Citations

0

Biochemical characterization and antibacterial activity of lipopolysaccharide binding proteins of the jellyfish Aurelia aurita and Rhopilema asamushi DOI

G. A. Naberezhnykh,

Aleksandra A. Yuferova,

С. И. Бахолдина

et al.

Fish & Shellfish Immunology, Journal Year: 2025, Volume and Issue: unknown, P. 110298 - 110298

Published: March 1, 2025

Language: Английский

Citations

0