Diversity of endophytic bacteria with antimicrobial potential isolated from marine macroalgae from Yacila and Cangrejos beaches, Piura-Peru DOI Creative Commons
Edwin Jorge Vega Portalatino,

Miriam Marleni Rosales Cuentas,

Carmen Tamariz Angeles

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: May 2, 2024

Abstract Endophytic bacteria from marine macroalgae (EBMM) have aroused interest for their antimicrobial activity, becoming a new source of bioactive compounds the control pathogenic bacteria, yeasts and fungi. EBMMs were isolated Caulerpa sp., Ulva Ahnfeltiopsis sp. Chondracantus chamissoi collected Yacila Cangrejo beach (Piura, Peru). Antimicrobial assays against evaluated by cross method, over plate test (OpT) volatile organic compound (VOCt). Bacteria with best antibacterial potential molecularly characterized, antifungal activity presence Iturin, Fengycin Surfactin genes. Forty-six EBMM isolated, most them phylum Rhodophyta group coming Yacila. In crossmatch evaluation, 10 found to inhibit gram-positive (Enterococcus faecalis, Staphylococcus epidermidis, aureus Listeria monocytogenes) 12 gram-negative (Escherichia coli Salmonella enteric sv typhimurium). These activities confirmed OpT VOCt. The selected strains identified as 4 Bacillus 2 Kluyvera ascorbata, 1 Pantoea agglomerans, Leclercia adecarboxylata Enterobacter strains, P. agglomerans YAFL6, YAFL1, YCFR6 YUFE8 showed high on Candida albicans, tropicalis, Colletotrichium Fusarium Fusarium oxysporum Alternaria addition, K. ascorbata YAFE21 YCFE4 Iturin results obtained show future applications in production metabolites control.

Language: Английский

Marine natural products DOI Creative Commons
Anthony R. Carroll, Brent R. Copp, Tanja Grkovic

et al.

Natural Product Reports, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

A comprehensive review of 1220 new MNPs including a novel sex inducing pheromone from the diatom Seminavis robusta .

Language: Английский

Citations

2
Characterization of a Novel Antimicrobial Peptide Bacipeptin against Foodborne Pathogens DOI

Xiaotong Wei,

Yuanyuan Hu, Chaomin Sun

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: 72(10), P. 5283 - 5292

Published: March 1, 2024

The increasing emergence of multidrug-resistant pathogens and development biopreservatives in food industries has increased the demand novel safe antimicrobial agents. In this study, a marine bacterial strain Bacillus licheniformis M1 was isolated exhibited obvious activities against foodborne pathogens, especially methicillin-resistant Staphylococcus aureus. agent purified identified as peptide, which designated bacipeptin, corresponding mechanism further investigated by electron microscopy observation transcriptomic analysis with biochemical validation. results showed that bacipeptin could reduce virulence aureus exerted its activity interfering histidine metabolism, inducing accumulation reactive oxygen species down-regulating genes related to Na+/H+ antiporter cell wall, thus causing damage wall membrane. Overall, our study provides natural product discloses action mechanism.

Language: Английский

Citations

5
Antimicrobial therapy based on self-assembling peptides DOI
Yuqi Wang,

Yexi Zhang,

Rongxin Su

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(21), P. 5061 - 5075

Published: Jan. 1, 2024

This paper describes the antimicrobial activity of self-assembled peptides, research progress and assembly strategies.

Language: Английский

Citations

5
Recent Advances in Marine-Derived Compounds as Potent Antibacterial and Antifungal Agents: A Comprehensive Review DOI Creative Commons
Devaraj Bharathi, Jintae Lee

Marine Drugs, Journal Year: 2024, Volume and Issue: 22(8), P. 348 - 348

Published: July 29, 2024

The increase in antimicrobial resistance (AMR) microorganisms is a significant global health concern. Various factors contribute to AMR, including alterations cell membrane permeability, increased efflux pump activity, enzymatic modification or inactivation of antibiotics, target site changes, alternative metabolic pathways, and biofilm formation. Marine environments, with their extensive biodiversity, provide valuable source natural products wide range biological activities. Marine-derived compounds show potential against drug-resistant bacteria fungi. This review discusses the current knowledge on marine such as microorganisms, sponges, tunicates mollusks antibacterial antifungal properties effective ecological roles. These are classified based chemical structures, alkaloids, amino acids, peptides, polyketides, naphthoquinones, terpenoids, polysaccharides. Although still preclinical studies, these agents demonstrate promising vivo efficacy, suggesting that sources could be pivotal developing new drugs combat thereby fulfilling an essential medical need. highlights ongoing importance biodiversity exploration for discovering agents.

Language: Английский

Citations

4
Diversity of endophytic bacteria with antimicrobial potential isolated from marine macroalgae from Yacila and Cangrejos beaches, Piura-Peru DOI Creative Commons
Edwin Jorge Vega Portalatino,

Miriam Marleni Rosales Cuentas,

Carmen Tamariz Angeles

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: May 2, 2024

Abstract Endophytic bacteria from marine macroalgae (EBMM) have aroused interest for their antimicrobial activity, becoming a new source of bioactive compounds the control pathogenic bacteria, yeasts and fungi. EBMMs were isolated Caulerpa sp., Ulva Ahnfeltiopsis sp. Chondracantus chamissoi collected Yacila Cangrejo beach (Piura, Peru). Antimicrobial assays against evaluated by cross method, over plate test (OpT) volatile organic compound (VOCt). Bacteria with best antibacterial potential molecularly characterized, antifungal activity presence Iturin, Fengycin Surfactin genes. Forty-six EBMM isolated, most them phylum Rhodophyta group coming Yacila. In crossmatch evaluation, 10 found to inhibit gram-positive (Enterococcus faecalis, Staphylococcus epidermidis, aureus Listeria monocytogenes) 12 gram-negative (Escherichia coli Salmonella enteric sv typhimurium). These activities confirmed OpT VOCt. The selected strains identified as 4 Bacillus 2 Kluyvera ascorbata, 1 Pantoea agglomerans, Leclercia adecarboxylata Enterobacter strains, P. agglomerans YAFL6, YAFL1, YCFR6 YUFE8 showed high on Candida albicans, tropicalis, Colletotrichium Fusarium Fusarium oxysporum Alternaria addition, K. ascorbata YAFE21 YCFE4 Iturin results obtained show future applications in production metabolites control.

Language: Английский

Citations

0