Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
96(39), P. 15640 - 15647
Published: Sept. 4, 2024
Collagen,
a
widely
used
biomaterial,
is
susceptible
to
denaturation
during
production
from
native
tissues,
posing
serious
challenges
for
its
applications
in
tissue
engineering.
Accurate
quantification
of
denatured
collagen
(DC)
essential
evaluating
the
quality
collagen-based
biomaterials,
yet
quantitative
methods
assessing
are
lacking.
Here,
we
first
time
present
highly
specific
biochip
sensitive
levels
(
Sustainability,
Journal Year:
2025,
Volume and Issue:
17(2), P. 720 - 720
Published: Jan. 17, 2025
Food
waste
and
food
by-products
have
gained
considerable
attention
in
recent
years.
Based
on
the
principles
of
circular
economy,
these
materials
can
be
used
for
preparation
novel
biodegradable
packaging
preservation.
Among
matrices
that
been
well
exploited,
poly-lactic
acid
(PLA)
comprises
a
key
material
to
fortified
with
by-products,
as
shown
by
numerous
studies
literature.
In
this
context,
aim
present
review
was
provide
an
overview
literature
most
trends
use
PLA
prepare
films
shelf-life
extension
foods
animal
or
plant
origin.
The
results
showed
origin
has
greatly
expanded
last
20
application
led
stability.
However,
there
is
still
gap
specific
origin,
such
peels,
seeds,
gels
(i.e.,
onion
grape
seed
extract,
pomace,
prickly
pear
cladode
gel)
whey,
collagen,
gelatin),
PLA-based
films.
review,
which
thematic
issue
ongoing
doctoral
study,
examines
challenges
regard
topic
not
extensively
studied.
International Journal of Molecular Sciences,
Journal Year:
2025,
Volume and Issue:
26(2), P. 663 - 663
Published: Jan. 14, 2025
Organoid
technology,
as
an
innovative
approach
in
biomedicine,
exhibits
promising
prospects
disease
modeling,
pharmaceutical
screening,
regenerative
medicine,
and
oncology
research.
However,
the
use
of
tumor-derived
Matrigel
primary
method
for
culturing
organoids
has
significantly
impeded
clinical
translation
organoid
technology
due
to
concerns
about
potential
risks,
batch-to-batch
instability,
high
costs.
To
address
these
challenges,
this
study
innovatively
introduced
a
photo-crosslinkable
hydrogel
made
from
porcine
small
intestinal
submucosa
decellularized
matrix
(SIS),
fish
collagen
(FC),
methacrylate
gelatin
(GelMA).
The
cost-effective
demonstrated
excellent
biocompatibility,
tunable
mechanical
properties,
rapid
gelation
low
immunogenicity.
Importantly,
proliferation
differentiation
capacities
cultured
were
comparable
those
Matrigel,
with
no
significant
disparity
observed.
Furthermore,
after
one
week
transplantation
nude
mice,
hydrogel-organoid
complex
exhibited
sustained
structural
functional
stability
while
preserving
characteristics
organoids.
Our
also
effective
FC/SIS/GelMA
accelerating
repair
process
defects,
reducing
area
scar
formation,
promoting
regeneration
both
villi
smooth
muscle
tissue.
In
summary,
presents
novel
protocol
organoids,
offering
implications
future
applications
serving
experimental
foundation
development
tissue-engineered
intestines
based
on
International Journal of Biological Macromolecules,
Journal Year:
2024,
Volume and Issue:
278, P. 134374 - 134374
Published: Aug. 3, 2024
The
consumption
of
animal
products
has
witnessed
a
significant
increase
over
the
years,
leading
to
growing
need
for
industries
adopt
strict
waste
control
measures
mitigate
environmental
impacts.
disposal
in
landfill
can
result
diverse
and
potentially
hazardous
decomposition
by-products.
Animal
by-products,
derived
from
meat,
poultry,
seafood
fish
industries,
offer
substantial
raw
material
source
collagen
gelatin
production
due
their
high
protein
content.
Collagen,
being
major
component
tissues,
represents
an
abundant
resource
that
finds
application
various
chemical
industries.
demand
collagen-based
continues
grow,
yet
availability
primary
remains
limited
insufficient
meet
projected
needs.
Consequently,
repurposing
materials
contain
provides
opportunity
this
while
at
same
time
minimizing
amount
is
dumped.
This
review
examines
potential
extract
value
content
present
animal-derived
It
systematic
evaluation
different
species
groups
discusses
approaches
processing
fabricating
repurposed
collagen.
specifically
focuses
on
research,
encompassing
examination
its
physical
properties,
as
well
modifications.
We
have
detailed
how
research
knowledge
built
structure
function
will
drive
new
initiatives
lead
development
opportunities
future.
Additionally,
it
highlights
emerging
extracting
high-quality
efforts
fabricate
original
within
chemical,
biomedical
science-based
Foods,
Journal Year:
2024,
Volume and Issue:
13(8), P. 1213 - 1213
Published: April 16, 2024
This
study
compared
collagens
from
cold-water
and
warm-water
fish
for
their
structural,
rheological,
functional
properties,
explored
potential
applications,
aiming
to
realize
the
high-value
utilization
of
marine
biological
resources.
To
this
end,
chum
salmon
skin
collagen
(CSSC)
Nile
tilapia
(NTSC)
were
both
successfully
extracted.
Collagens
two
species
had
different
primary
secondary
structures,
with
NTSC
having
a
higher
molecular
weight,
imino
acid
content,
α-helices
β-turns
content.
The
denaturation
temperatures
12.01
°C
CSSC
31.31
NTSC.
was
dominated
by
viscous
behavior
its
structure
varied
temperature,
while
elastic
remained
stable
temperature.
Both
good
oil
holding
capacity,
foaming
emulsifying
activity,
but
better
water
capacity
stability.
Their
properties
make
more
suitable
preservation
frozen
chilled
foods
production
sparkling
beverages,
give
greater
in
biofunctional
materials
solid
food
processing.
