Antibiotics, Journal Year: 2025, Volume and Issue: 14(4), P. 394 - 394

Published: April 10, 2025

The global spread of antimicrobial resistance (AMR) threatens to plummet society back the pre-antibiotic era through a resurgence common everyday infections’ morbidity. Thus, studies investigating antibiotic genes (ARGs) and antibiotic-resistant bacteria (ARB) in urban, agricultural, clinical settings, as well extreme environments, have become increasingly relevant One Health perspective. Since Antarctic Arctic regions are considered amongst few remaining pristine environments on Earth, characterization their native resistome appears be utmost importance understand whether how it is evolving result anthropogenic activities climate change. In present review, we report phenotypic (e.g., disk diffusion test) genotypic PCR, metagenomics) approaches used study AMR aquatic environment polar regions, water represents one main dissemination routes nature. Their advantages limits described, emerging trends resulting from analysis ARB ARGs waters discussed. detected these mostly comparable those more anthropized areas, with predominance tetracycline, β-lactam, sulfonamide (and related ARGs). Indeed, is, all cases, consistently highlighted sites impacted by human wildlife respect ones. Surprisingly, aminoglycoside fluroquinolone determinants seem an even higher incidence compared that other areas world, corroborating need for thorough surveillance regions.

Language: Английский