
The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 958, P. 177982 - 177982
Published: Dec. 10, 2024
Language: Английский
The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 958, P. 177982 - 177982
Published: Dec. 10, 2024
Language: Английский
Phycology, Journal Year: 2025, Volume and Issue: 5(1), P. 7 - 7
Published: Feb. 17, 2025
This study aimed at producing a sourdough bread supplemented with two marine algae powders of Ulva lactuca and Gelidium corneum 2.5, 5, 7.5, 10% (w/w, g/100 g DW) the laboratory scale using mixed starters prepared three lactic acid bacteria (LAB) combinations (LCS1, LCS2, LCS3). The phytochemical composition, nutritional value, organoleptic properties, acceptability by consumers were then assessed. Good results obtained for enriched 2.5% (GB1) reducing sugar 0.77 ± 0.1%, total 36.90 3.15, protein content 8.3 0.2%. While phenolic was 8.32 1.20 mg GAE/g DW, flavonoids 225.00 11.31 mgQE/g antioxidant activity ranged from 71.05 3.71 to 82.93 3.61%. Regarding (UB12), 0.48 0.03%, 45.45 5.75%, 3.7 0.07%. value 6.45 1.19 191.20 12.52 while values 52.06 6.21 80.51 1.72%. Microbiological analysis showed that all pathogenic not detected in bread. consumer test revealed level powder significant five selected criteria (general appearance, crumb color, odor, taste, texture). Traditional 10%, combined (LCS1), good properties acceptance.
Language: Английский
Citations
0BMC Biotechnology, Journal Year: 2025, Volume and Issue: 25(1)
Published: March 4, 2025
Algae are microscopic or macroscopic organisms that can photosynthesize and found in both freshwater saltwater ecosystems considered one of the cornerstones life. In our study, biological activities extracts produced under extract conditions provided highest activity Ulva lactuca L. were determined. Two different methods, Response Surface Method (RSM) Artificial Neural Network-Genetic Algorithm (ANN-GA) integration used for optimization. this context, optimum determined as 54.940 ˚C temperature, 6.513 h, 42.109 ethanol/water ratio according to RSM method 56.286 7.2793 36.8625 ANN-GA. The antioxidant optimized evaluated by Rel Assay kits, DPPH FRAP methods. Anticholinesterase testing against acetylcholinesterase butyrylcholinesterase enzymes. addition, antiproliferative effects examined A549 lung cancer cell line phenolic compound contents analyzed LC-MS/MS. As a result analyzes, it was seen obtained from recommended ANN-GA exhibited higher activities. Optimized U. have potential terms total value 6.272 ± 0.024 mmol/L. showed strong cytotoxic line. gallic acid, 4-hydroxybenzoic caffeic vanillic syringic quercetin kaempferol algae conditions. detected acid. addition all these properties, has anticholinesterase study. conclusion, attract attention with their well be source treatment management neurological diseases.
Language: Английский
Citations
0Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16
Published: March 10, 2025
Background The increasing demand for natural alternatives in diabetes treatment has driven research into plant-derived metabolites, particularly essential oils (EOs) with bioactive properties. This study aims to optimize an EO mixture inhibiting two key enzymes involved glucose digestion: pancreatic α-amylase and intestinal α-glucosidase. Methods Essential were extracted from three Moroccan medicinal plants: false yellowhead ( Inula viscosa L.), rose geranium Pelargonium graveolens L'Hér.), lemongrass Cymbopogon citratus (DC.) Stapf.). Gas chromatography-mass spectrometry (GC-MS) analysis identified metabolites each EO. A statistical design was employed evaluate different ratios their inhibitory effects on Additionally, density functional theory (DFT) calculations molecular docking simulations conducted assess the metabolites' electronic properties interaction potential target enzymes. Results GC-MS 32 P . , citronellol (18.67%), eucalyptol (13.30%), 2-octen-1-ol (8.12%) as major components. I contained 18 dominated by 2-camphanol acetate (51.12%) camphol (19.32%), while C. had 23 α-citral (24.70%) 2-isopropenyl-5-methylhex-4-enal (29.25%) constituents. optimal formulation α-glucosidase inhibition a binary of 73% 27% P. In contrast, best blend consisted 56% 44% I. DFT confirmed electrophilic nature supporting enzyme interaction. Molecular suggested that these phytochemicals could exhibit stronger than acarbose, widely used antidiabetic drug. Conclusion These findings highlight optimized formulations managing hyperglycemia developing novel therapies.
Language: Английский
Citations
0Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 144310 - 144310
Published: April 1, 2025
Language: Английский
Citations
0The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 958, P. 177982 - 177982
Published: Dec. 10, 2024
Language: Английский
Citations
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