Molecular Docking and Experimental Analysis of Essential Oil-Based Preparations on Biofilm Formation on Orthodontic Archwires DOI Open Access
Vlad Tiberiu Alexa, Aurora Doris Fratila, Roxana Oancea

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(24), P. 13378 - 13378

Published: Dec. 13, 2024

Good oral hygiene is crucial during treatment with fixed appliances, emphasising the need for additional or alternative health methods orthodontic treatment. This study investigates effect of essential oil (EO)-based preparations on biofilm adhesion to archwires. Five identical-sized archwires different materials were tested using therapeutic and preventive applications oils. also used molecular docking explore how compounds interact key proteins common pathogens like Staphylococcus aureus Streptococcus mutans. We found that constituent heavily influence antimicrobial effects oils Stainless steel-based demonstrated highest efficacy in protection against S. mutans strains (maximum BIP = 28.82% epoxy-coated SS). Conversely, inhibition observed exclusively titanium–molybdenum alloy across all emulsions 29.44%). CuNiTi alloys showed ineffectiveness treatments, as none EO mixtures inhibited development this material. After contamination aureuss strains, ternary emulsion was most effective four out five Computational analysis revealed strong binding interactions between mutans, highlighting specific amino acid residues are critical these interactions. Based results, stainless steel epoxy coating TMA archwires, combined BEO/CEO/OEO mixture, recommended optimal antibacterial formation

Language: Английский

Applications of nanotechnology in orthodontics: a comprehensive review of tooth movement, antibacterial properties, friction reduction, and corrosion resistance DOI Creative Commons
Longwen He, Wenzhong Zhang, Junfeng Liu

et al.

BioMedical Engineering OnLine, Journal Year: 2024, Volume and Issue: 23(1)

Published: July 25, 2024

Abstract Nanotechnology has contributed important innovations to medicine and dentistry, also offered various applications the field of orthodontics. Intraoral appliances must function in a complex environment that includes digestive enzymes, diverse microbiome, mechanical stress, fluctuations pH temperature. can improve performance orthodontic brackets archwires by reducing friction, inhibiting bacterial growth biofilm formation, optimizing tooth remineralization, improving corrosion resistance biocompatibility metal substrates, accelerating or decelerating movement through application novel nanocoatings, nanoelectromechanical systems, nanorobots. This comprehensive review systematically explores nanotechnology, particularly its impacts on movement, antibacterial activity, friction reduction, resistance. A search across PubMed, Web Science Core Collection, Google Scholar yielded 261 papers, which 28 met our inclusion criteria. These selected studies highlight significant benefits nanotechnology devices. Recent clinical trials demonstrate advancements brought may facilitate future delivery more effective comfortable care.

Language: Английский

Citations

4
The influence of low nitrogen doping on bacterial adhesion of sputtered a-C:H coatings DOI Creative Commons
António Fróis, Romeu Francisco, Paula V. Morais

et al.

Diamond and Related Materials, Journal Year: 2024, Volume and Issue: 147, P. 111309 - 111309

Published: June 14, 2024

Heavily dependent on both surface and bacteria characteristics, multiple complex parameters control bacterial adhesion to any biomaterial surface. That's why there are so many contradictory results regarding the antibacterial inhibition properties of Diamond-Like Carbon (DLC) protective coatings, despite well-established biocompatibility this very broad group materials. Aiming at Orthodontics, study reports modification hydrogenated amorphous carbon coatings (a-C:H), by nitrogen incorporation upon reactive magnetron sputtering. The effect low N content up 10 at.% microstructure was studied. Despite progressive graphitization doping, roughness not significantly influenced water contact angles remained above 70°. three strains Staphylococcus aureus, Bacillus subtilis Pseudomonas aeruginosa evaluated. median colony forming units lower a-C:H a-C:H:N in comparison bare AISI 316L medical grade stainless steel surface, regardless strain. best capacity achieved for doping 6 at.%, without using agents.

Language: Английский

Citations

2
The Effect of Electroless Nickel–Polytetrafluoroethylene Coating on the Frictional Properties of Orthodontic Wires DOI Creative Commons
Kento Numazaki, Masatoshi Takahashi,

Arata Ito

et al.

Metals, Journal Year: 2024, Volume and Issue: 14(2), P. 213 - 213

Published: Feb. 9, 2024

In orthodontic treatment, to achieve efficient tooth movement, it is important reduce the frictional force between wire and bracket, especially binding friction that occurs when angle bracket large. Electroless nickel–polytetrafluoroethylene (Ni-PTFE) coating a technology used deposit PTFE particles with low coefficient of on surface provide low-friction for metallic materials. The purpose this study was investigate effect Ni-PTFE-coated wires brackets. morphology, roughness, properties stainless steel Ni-Ti were evaluated. results demonstrate Ni-PTFE reduced brackets, despite increased roughness. Even increased, assuming friction, by coating. This suggests suppressed deposited in contact bracket.

Language: Английский

Citations

1
Metal Release and Cell Viability of 316L Stainless Steel Sputter-Coated with N-Doped a-C:H Coatings DOI Creative Commons
António Fróis, João Carlos Marques, Luís F. Santos

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(22), P. 10500 - 10500

Published: Nov. 14, 2024

Hydrogenated amorphous carbon (a-C:H) has been considered a promising biocompatible coating to protect metallic alloys against corrosion for medical applications, namely orthodontics. However, there is still no optimal solution this biomedical field; hence, the investigation remains open. In work, effect of nonmetallic doping element (N) on sputter-deposited a-C:H coatings was studied concerning both salivary and cytotoxicity behavior. After 30-day test in an acidic modified Fusayama-Meyer artificial saliva, metal release from coated uncoated 316L stainless steel (SS) substrates quantified. Tests extracts were then performed by using monocultures macrophages fibroblasts, their coculture; cell viability evaluated via MTT test. Results show overall inhibition SS corrosion, which enhanced vitro biocompatibility with minimal coatings’ microstructure. Among all tested, undoped best, whereas increase N led poorer protection dissolution subsequent slightly lower biocompatibility. The findings corroborate that selecting C-based not good choice field, even at low contents up 10 at.%.

Language: Английский

Citations

1
Simulation of an Orthodontic System Using the Lingual Technique Based on the Finite Element Method DOI Creative Commons

Abbas Hazem,

Felicia Ileana Mărășescu,

Mihaela Jana Ţuculină

et al.

Diagnostics, Journal Year: 2024, Volume and Issue: 14(24), P. 2832 - 2832

Published: Dec. 16, 2024

Backgrounds/Objectives: The finite element method (FEM) is an advanced numerical technique that can be applied in orthodontics to study tooth movements, stresses, and deformations occur during orthodontic treatment. It also useful for simulating visualizing the biomechanical behavior of teeth, tissues, appliances various clinical scenarios. objective this research was analyze mechanical Materials Methods: For study, we utilized a model derived from set CBCT scans 26-year-old female patient who underwent fixed treatment using lingual technique. Through series programs based on reverse engineering, constructed three-dimensional reconstruction teeth their internal structures. Using (FEM), obtained six simulations system utilizing technique, which employed brackets made chrome–nickel or gold, archwires nitinol, stainless steel. Results: reveals although deformation same, forces generated by three types differ. variation essential customizing treatment, as these must precisely controlled ensure effective movement prevent overloading dental Conclusions: FEM analysis allows identification ideal combinations between materials used brackets. This ensures optimal intensity results desired movements without causing damage enamel, dentin, pulp teeth.

Language: Английский

Citations

1
Orthodontic Alloy Wires and Their Hypoallergenic Alternatives: Metal Ions Release in pH 6.6 and pH 5.5 Artificial Saliva DOI Open Access
Zana Jusufi Osmani, Petra Tariba Knežević,

Davor Vučinić

et al.

Materials, Journal Year: 2024, Volume and Issue: 17(21), P. 5254 - 5254

Published: Oct. 29, 2024

Legislative framework addresses the issues of alloy corrosion, demanding restricted use probable carcinogenic, mutagenic, and toxic-for-human-reproduction (CMG) metals like nickel, cobalt, chromium development new biomaterials. The aim this research was to evaluate compare ion release standard dental alloys their hypoallergenic equivalents. Six types orthodontic wires (nickel–titanium (NiTi), coated NiTi, stainless steel (SS), Ni-free SS, cobalt–chromium (CoCr) titanium–molybdenum (TMA) were immersed into artificial saliva pH 5.5 6.6. Release metal ions measured by inductively coupled plasma–mass spectrometry after 3, 7, 14 28 days. data analyzed using analysis variance, results with p < 0.05 considered significant. NiTi released more Ti Ni compared NiTi; SS iron, chromium, nickel nickel-free SS. CoCr cobalt in a high concentration low amounts molybdenum titanium TMA. from vitro overall lower at 6.6 for equivalents when alloys.

Language: Английский

Citations

0
Molecular Docking and Experimental Analysis of Essential Oil-Based Preparations on Biofilm Formation on Orthodontic Archwires DOI Open Access
Vlad Tiberiu Alexa, Aurora Doris Fratila, Roxana Oancea

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(24), P. 13378 - 13378

Published: Dec. 13, 2024

Good oral hygiene is crucial during treatment with fixed appliances, emphasising the need for additional or alternative health methods orthodontic treatment. This study investigates effect of essential oil (EO)-based preparations on biofilm adhesion to archwires. Five identical-sized archwires different materials were tested using therapeutic and preventive applications oils. also used molecular docking explore how compounds interact key proteins common pathogens like Staphylococcus aureus Streptococcus mutans. We found that constituent heavily influence antimicrobial effects oils Stainless steel-based demonstrated highest efficacy in protection against S. mutans strains (maximum BIP = 28.82% epoxy-coated SS). Conversely, inhibition observed exclusively titanium–molybdenum alloy across all emulsions 29.44%). CuNiTi alloys showed ineffectiveness treatments, as none EO mixtures inhibited development this material. After contamination aureuss strains, ternary emulsion was most effective four out five Computational analysis revealed strong binding interactions between mutans, highlighting specific amino acid residues are critical these interactions. Based results, stainless steel epoxy coating TMA archwires, combined BEO/CEO/OEO mixture, recommended optimal antibacterial formation

Language: Английский

Citations

0