Decoding Metabolic Reprogramming in Plants under Pathogen Attacks, a Comprehensive Review of Emerging Metabolomics Technologies to Maximize Their Applications DOI Creative Commons
Ahmed Serag, Mohamed A. Salem, Shilin Gong

et al.

Metabolites, Journal Year: 2023, Volume and Issue: 13(3), P. 424 - 424

Published: March 13, 2023

In their environment, plants interact with a multitude of living organisms and have to cope large variety aggressions biotic or abiotic origin. What has been known for several decades is that the extraordinary chemical compounds are capable synthesizing may be estimated in range hundreds thousands, but only fraction fully characterized implicated defense responses. Despite vast importance these metabolites also human health, our knowledge about biosynthetic pathways functions still fragmentary. Recent progress made particularly phenylpropanoids oxylipids metabolism, which more emphasized this review. With an increasing interest monitoring plant metabolic reprogramming, development advanced analysis methods should now follow. This review capitalizes on technologies used metabolome mapping planta, including different metabolomics approaches, imaging, flux analysis, interpretation using bioinformatics tools. Advantages limitations regards application each technique towards metabolite class type highlighted, special emphasis necessary future developments better mirror such intricate interactions planta.

Language: Английский

How do plants defend themselves against pathogens-Biochemical mechanisms and genetic interventions DOI Creative Commons

Simardeep Kaur,

Mahesh Kumar Samota, Manoj Choudhary

et al.

Physiology and Molecular Biology of Plants, Journal Year: 2022, Volume and Issue: 28(2), P. 485 - 504

Published: Feb. 1, 2022

Abstract In agro-ecosystem, plant pathogens hamper food quality, crop yield, and global security. Manipulation of naturally occurring defense mechanisms in host plants is an effective sustainable approach for disease management. Various natural compounds, ranging from cell wall components to metabolic enzymes have been reported protect infection by hence provide specific resistance hosts against pathogens, termed as induced resistance. It involves various biochemical components, that play important role molecular cellular signaling events either before (elicitation) or after pathogen infection. The induction reactive oxygen species, activation defensive machinery comprising enzymatic non-enzymatic antioxidative secondary metabolites, pathogenesis-related protein expression (e.g. chitinases glucanases), phytoalexin production, modification composition, melatonin carotenoids accumulation, altered activity polyamines are major changes during Hence, the concentration restricts development. Such markers can be harnessed development “pathogen-proof” plants. Effective utilization key metabolites-based pave path candidate gene identification. This present review discusses valuable information understanding response mechanism cope with genomics-metabolomics-based proof cultivars along knowledge gaps future perspectives enhance agricultural production.

Language: Английский

Citations

251
Metabolomics-centered mining of plant metabolic diversity and function: Past decade and future perspectives DOI Creative Commons
Shuangqian Shen, Chuansong Zhan, Chenkun Yang

et al.

Molecular Plant, Journal Year: 2022, Volume and Issue: 16(1), P. 43 - 63

Published: Sept. 16, 2022

Language: Английский

Citations

142
Past and Future of Plant Stress Detection: An Overview From Remote Sensing to Positron Emission Tomography DOI Creative Commons
Angelica Galieni, N. d’Ascenzo, Fabio Stagnari

et al.

Frontiers in Plant Science, Journal Year: 2021, Volume and Issue: 11

Published: Jan. 27, 2021

Plant stress detection is considered one of the most critical areas for improvement crop yield in compelling worldwide scenario, dictated by both climate change and geopolitical consequences Covid-19 epidemics. A complicated interconnection biotic abiotic stressors affect plant growth, including water, salt, temperature, light exposure, nutrients availability, agrochemicals, air soil pollutants, pests diseases. In facing this extended panorama, technology choice manifold. On hand, quantitative methods, such as metabolomics, provide very sensitive indicators stressors, with drawback a disruptive approach, which prevents follow up dynamical studies. other hand qualitative fluorescence, thermography VIS/NIR reflectance, non-disruptive view action plants, even across large fields, poor accuracy. When looking at spatial scale, effect may imply modifications from DNA level (nanometers) to cell (micrometers), full (millimeters meters), entire field (kilometers). While techniques are smallest scales, only approaches can be used larger ones. Emerging technologies nuclear medical physics, computed tomography, magnetic resonance imaging positron emission expected bridge gap morphologic functional measurements scale. review we analyze landscape different nowadays available, showing benefits each approach detection, particular focus on gaps, will filled nearby future emerging physics agriculture.

Language: Английский

Citations

115
PGPR: the treasure of multifarious beneficial microorganisms for nutrient mobilization, pest biocontrol and plant growth promotion in field crops DOI
Dipak T. Nagrale, Anurag Chaurasia, Sunil Kumar

et al.

World Journal of Microbiology and Biotechnology, Journal Year: 2023, Volume and Issue: 39(4)

Published: Feb. 16, 2023

Language: Английский

Citations

68
Harnessing root exudates for plant microbiome engineering and stress resistance in plants DOI Creative Commons
Muhammad Siddique Afridi, Ashwani Kumar, Muhammad Ammar Javed

et al.

Microbiological Research, Journal Year: 2023, Volume and Issue: 279, P. 127564 - 127564

Published: Dec. 1, 2023

Language: Английский

Citations

42
Screening of soybean antifungal isoflavones based on targeted metabolomics analysis DOI Creative Commons

Nishbah Mughal,

Xiaowen Zhang, Noman Shoaib

et al.

Food Chemistry X, Journal Year: 2025, Volume and Issue: 25, P. 102195 - 102195

Published: Jan. 1, 2025

Language: Английский

Citations

2
Engineering disease resistant plants through CRISPR-Cas9 technology DOI Creative Commons
Swati Tyagi,

Robin Kumar,

Vivak Kumar

et al.

GM crops & food, Journal Year: 2020, Volume and Issue: 12(1), P. 125 - 144

Published: Oct. 20, 2020

Plants are susceptible to phytopathogens, including bacteria, fungi, and viruses, which cause colossal financial shortfalls (pre- post-harvest) threaten global food safety. To combat with these plant possesses two-layer of defense in the form PAMP-triggered immunity (PTI), or Effectors-triggered (ETI). The understanding plant-molecular interactions revolution high-throughput molecular techniques have opened door for innovations developing pathogen-resistant plants. In this context, Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR-associated protein 9 (Cas9) has transformed genome editing (GE) technology being harnessed altering traits. Here we summarized complexities immune system use CRISPR-Cas9 edit various components acquire long-lasting resistance plants against phytopathogens. This review also sheds light on limitations system, regulation edited crops future prospective technology.

Language: Английский

Citations

80
Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests DOI Creative Commons
Florence Castelli, Giulio Rosati, Christian Moguet

et al.

Analytical and Bioanalytical Chemistry, Journal Year: 2021, Volume and Issue: 414(2), P. 759 - 789

Published: Aug. 25, 2021

Abstract Metabolomics refers to the large-scale detection, quantification, and analysis of small molecules (metabolites) in biological media. Although metabolomics, alone or combined with other omics data, has already demonstrated its relevance for patient stratification frame research projects clinical studies, much remains be done move this approach practice. This is especially true perspective being applied personalized/precision medicine, which aims at stratifying patients according their risk developing diseases, tailoring medical treatments individual characteristics order improve efficacy limit toxicity. In review article, we discuss main challenges linked analytical chemistry that need addressed foster implementation metabolomics clinics use data produced by personalized medicine. First all, there are well-known issues related untargeted workflows levels production (lack standardization), metabolite identification (small proportion annotated features identified metabolites), processing (from automatic detection multi-omic integration) hamper inter-operability reusability data. Furthermore, outputs complex molecular signatures few tens metabolites, often abundance variations, obtained expensive laboratory equipment. It thus necessary simplify these so they can used field. last point, still poorly community, may crucial a near future increased availability societal demand participatory Graphical abstract

Language: Английский

Citations

78
Effector Biology of Biotrophic Plant Fungal Pathogens: Current Advances and Future Prospects DOI Creative Commons
Rajdeep Jaswal,

Kanti Kiran,

Sivasubramanian Rajarammohan

et al.

Microbiological Research, Journal Year: 2020, Volume and Issue: 241, P. 126567 - 126567

Published: Aug. 23, 2020

Language: Английский

Citations

73
Environmental and Genetic Factors Involved in Plant Protection-Associated Secondary Metabolite Biosynthesis Pathways DOI Creative Commons

Xiaori Zhan,

Zhehao Chen, Rong Chen

et al.

Frontiers in Plant Science, Journal Year: 2022, Volume and Issue: 13

Published: April 8, 2022

Plant specialized metabolites (PSMs) play essential roles in the adaptation to harsh environments and function plant defense responses. PSMs act as key components of defense-related signaling pathways trigger extensive expression genes. In addition, serve antioxidants, participating scavenging rapidly rising reactive oxygen species, chelators, chelation toxins under stress conditions. include nitrogen-containing chemical compounds, terpenoids/isoprenoids, phenolics. Each category secondary has a specific biosynthetic pathway, including precursors, intermediates, end products. The basic representative are summarized, providing potential target enzymes stress-mediated regulation Multiple metabolic share same origin, common frequently be targets regulation. Most controlled by different environmental genetic factors. Here, we summarized effects factors, abiotic biotic stresses, on PSM biosynthesis various plants. We also discuss positive negative transcription factors involved pathways. genes stress-related were summarized. further found that downstream these Transcription (TFs) enriched synthesis pathway suggesting an effective role precursors enhancing terminal present review provides valuable insights regarding screening regulators PSM-mediated protection non-model

Language: Английский

Citations

66