Nanomaterials-based portable electrochemical sensing and biosensing systems for clinical and biomedical applications DOI Creative Commons
Govindhan Maduraiveeran

Journal of Analytical Science & Technology, Journal Year: 2022, Volume and Issue: 13(1)

Published: Oct. 7, 2022

Abstract Miniaturized electrochemical sensing systems are employed in day-to-day uses the several area from public health to scientific applications. A variety of sensor and biosensor may not be effectively real-world diagnostic laboratories biomedical industries due their limitation portability, cost, analytical period, need skilled trainer for operating devices. The design smart portable sensors with high sensitivity, good selectivity, rapid measurement, reusable platforms is driving strength glucose, lactate, hydrogen peroxide, nitric oxide, mRNA, etc. enhancement abilities such devices through incorporation both novel sensitive nanomaterials strategies evidenced. Miniaturization, cost energy efficient, online quantitative detection multiple ability beneficial nanostructured-material-based systems. Owing discriminating catalytic action, solidity biocompatibility designing system, nanoscale materials empowered accomplished being entrenched into/combined or miniaturized specific In this review, advance development sensing/biosensing derived clinical applications described. Graphical

Language: Английский

Electrochemical Detection of H2O2Using an Activated Glassy Carbon Electrode DOI Creative Commons
Preethika Murugan,

Ramila D. Nagarajan,

Ashok K. Sundramoorthy

et al.

ECS Sensors Plus, Journal Year: 2022, Volume and Issue: 1(3), P. 034401 - 034401

Published: June 28, 2022

Hydrogen peroxide (H 2 O ) is extensively used for sterilization purposes in the food industries and pharmaceuticals as an antimicrobial agent. According to Food Agriculture Organization (FAO), permissible level of H milk range 0.04 0.05% w/v, so it has been prohibited use a preservative Herein, we reported electrochemical sensing samples using activated glassy carbon electrode (AGCE). For this purpose, activation GCE was carried out 0.1 M SO 4 by continuous potential sweeping between −0.7 1.8 V 25 cycles. The AGCE showed redox peak at -0.18 neutral medium corresponding quinone functional groups present on surface. studied (pH 7.4) PBS electro-catalysis . surface analysed Raman spectroscopy contact angle measurements. In addition, surface, found be 85° which indicated hydrophilic nature different optimization parameters such (1) effect electrolyte ions, (2) electrooxidation cycles, (3) oxidation windows were improve process. Finally, detect from 10 mM limit detection (LOD) 0.053 with linear correlation coefficient (R 0.9633. selectivity sensor towards presence other interferents. sensitivity calculated 17.16 μ A mol cm −2 commercial application verified testing recovery 95%–98%.

Language: Английский

Citations

96

Application of Two-Dimensional MXene materials in sensors DOI Creative Commons
Kefeng Xie, Jie Wang, Shengyuan Xu

et al.

Materials & Design, Journal Year: 2023, Volume and Issue: 228, P. 111867 - 111867

Published: March 27, 2023

Transition metal carbides and nitrides/carbonitrides (MXenes) with satisfactory conductivity, high specific surface area excellent hydrophilicity have attracted the attention of many researchers in field electrochemical sensors recent years. Etched MXenes usually show an accordion-like morphology; moreover, monolayer exhibit better electrical conductivity mechanical properties. The electronic chemical properties can be significantly changed by means compounding, hybridization modification. large areas used biosensors as carriers for recognition elements to achieve direct electron transfer target analytes. In addition, biological compatibility so that they incorporated into receptors without affecting activity. combined other oxide nanoparticles expand electrode while reducing overpotential effect electroanalysis process enhance catalytic MXene-based detecting strain, pressure, temperature, gas, various biomarkers, some environmental pollutants, use major research fields are summarized. future challenges research, development applications sensing discussed.

Language: Английский

Citations

59

A Nanotechnology-Based Approach to Biosensor Application in Current Diabetes Management Practices DOI Creative Commons
Ambreen Shoaib, Ali Darraj, Mohammad Ehtisham Khan

et al.

Nanomaterials, Journal Year: 2023, Volume and Issue: 13(5), P. 867 - 867

Published: Feb. 26, 2023

Diabetes mellitus is linked to both short-term and long-term health problems. Therefore, its detection at a very basic stage of utmost importance. Research institutes medical organizations are increasingly using cost-effective biosensors monitor human biological processes provide precise diagnoses. Biosensors aid in accurate diabetes diagnosis monitoring for efficient treatment management. Recent attention nanotechnology the fast-evolving area biosensing has facilitated advancement new sensors sensing improved performance sensitivity current biosensors. Nanotechnology detect disease track therapy response. Clinically user-friendly, efficient, cheap, scalable nanomaterial-based production thus can transform outcomes. This article more focused on their substantial applications. The highlights consist different types units, role diabetes, evolution glucose sensors, printed systems. Later on, we were engrossed based biofluids, employing minimally invasive, noninvasive technologies find out impact produce novel device as nano-biosensor. In this approach, documents major advances nanotechnology-based applications, well hurdles they must overcome clinical practice.

Language: Английский

Citations

57

MXene sensors based on optical and electrical sensing signals: from biological, chemical, and physical sensing to emerging intelligent and bionic devices DOI Creative Commons
Leiming Wu, Xixi Yuan,

Yuxuan Tang

et al.

PhotoniX, Journal Year: 2023, Volume and Issue: 4(1)

Published: May 5, 2023

Abstract Sensing devices are key nodes for information detection, processing, and conversion widely applied in different fields such as industrial production, environmental monitoring, defense. However, increasing demand of these has complicated the application scenarios diversified detection targets thereby promoting continuous development sensing materials methods. In recent years, Ti n+1 C n T x ( = 1, 2, 3) MXenes with outstanding optical, electrical, thermal, mechanical properties have been developed ideal candidates to apply physical, chemical, biological fields. this review, depending on optical electrical signals, we systematically summarize nine categories sensors strain, gas, fluorescence sensors. The excellent allow its further emerging intelligent bionic devices, including smart flexible E-skin, neural network coding learning, soft robot, well artificial eardrum, which all discussed briefly review. Finally, present a positive outlook potential future challenges perspectives MXene-based shown vigorous momentum applications can drive an number new technologies.

Language: Английский

Citations

54

Recent Developments in the Design and Fabrication of Electrochemical Biosensors Using Functional Materials and Molecules DOI Creative Commons

K. Theyagarajan,

Young‐Joon Kim

Biosensors, Journal Year: 2023, Volume and Issue: 13(4), P. 424 - 424

Published: March 27, 2023

Electrochemical biosensors are superior technologies that used to detect or sense biologically and environmentally significant analytes in a laboratory environment, even the form of portable handheld wearable electronics. Recently, imprinted implantable emerging as point-of-care devices, which monitor target continuous environment alert intended users anomalies. The stability performance developed biosensor depend on nature properties electrode material platform is constructed. Therefore, plays an integral role effectiveness biosensor. Enormous effort has been dedicated rational design fabrication strategies for improving biosensors. Every year, search multifarious materials, thousands new platforms reported. Moreover, order construct effectual biosensor, researcher should familiarize themself with sensible behind fabrication. Thus, we intend shed light various methodologies utilized electrochemical facilitate sensitive selective detection analytes. Furthermore, this review highlights advantages materials correlation between immobilized biomolecules modified surfaces.

Language: Английский

Citations

43

Macromolecule–Nanoparticle-Based Hybrid Materials for Biosensor Applications DOI Creative Commons

Giddaerappa Kuntoji,

Naseem Kousar,

Shivalingayya Gaddimath

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(6), P. 277 - 277

Published: May 28, 2024

Biosensors function as sophisticated devices, converting biochemical reactions into electrical signals. Contemporary emphasis on developing biosensor devices with refined sensitivity and selectivity is critical due to their extensive functional capabilities. However, a significant challenge lies in the binding affinity of biosensors biomolecules, requiring adept conversion amplification interactions various signal modalities like electrical, optical, gravimetric, electrochemical outputs. Overcoming challenges associated sensitivity, detection limits, response time, reproducibility, stability essential for efficient creation. The central aspect fabrication any focused towards forming an effective interface between analyte electrode which significantly influences overall quality. Polymers macromolecular systems are favored distinct properties versatile applications. Enhancing conductivity these can be achieved through incorporating nanoparticles or carbonaceous moieties. Hybrid composite materials, possessing unique combination attributes advanced selectivity, thermal stability, mechanical flexibility, biocompatibility, tunable properties, emerge promising candidates In addition, this approach enhances response, amplification, fabricated biosensors, contributing effectiveness. This review predominantly explores recent advancements utilizing macrocyclic conjugated systems, such phthalocyanines, porphyrins, polymers, etc. hybrids, specific focus biosensors. It comprehensively covers synthetic strategies, working mechanisms, potential detecting biomolecules glucose, hydrogen peroxide, uric acid, ascorbic dopamine, cholesterol, amino acids, cancer cells. Furthermore, delves progress made, elucidating mechanisms responsible amplification. Conclusion addresses future directions macromolecule-based hybrids applications, providing concise overview evolving field. narrative emphasizes importance technology advancement, illustrating role smart design material enhancement improving performance across domains.

Language: Английский

Citations

30

MXene-based electrochemical devices applied for healthcare applications DOI Creative Commons
Lenka Lorencová, Peter Kasák, Natália Košútová

et al.

Microchimica Acta, Journal Year: 2024, Volume and Issue: 191(2)

Published: Jan. 11, 2024

Abstract The initial part of the review provides an extensive overview about MXenes as novel and exciting 2D nanomaterials describing their basic physico-chemical features, methods synthesis, possible interfacial modifications techniques, which could be applied to characterization MXenes. Unique parameters make them attractive for many practical applications, are shortly discussed. Use healthcare applications is a hot scientific discipline discussed in detail. article focuses on determination low molecular weight analytes (metabolites), high (DNA/RNA proteins), or even cells, exosomes, viruses detected using electrochemical sensors biosensors. Separate chapters provided show potential MXene-based devices cancer biomarkers wearable biosensors monitoring wide range human activities. Graphical

Language: Английский

Citations

24

MXene/CNTs/Cu-MOF electrochemical probe for detecting tyrosine DOI
Jing Chen, Ying Chen, Shuying Li

et al.

Carbon, Journal Year: 2022, Volume and Issue: 199, P. 110 - 118

Published: July 18, 2022

Language: Английский

Citations

58

2D MXene/graphene nanocomposite preparation and its electrochemical performance towards the identification of nicotine level in human saliva DOI
Jerome Rajendran, Ashok K. Sundramoorthy,

Dhanraj Ganapathy

et al.

Journal of Hazardous Materials, Journal Year: 2022, Volume and Issue: 440, P. 129705 - 129705

Published: Aug. 3, 2022

Language: Английский

Citations

50

Recent advances in electrochemical non-enzymatic glucose sensor for the detection of glucose in tears and saliva: A Review DOI

Kermue Vasco Jarnda,

Danqi Wang, Qurrat-ul-Ain Qurrat-ul-Ain

et al.

Sensors and Actuators A Physical, Journal Year: 2023, Volume and Issue: 363, P. 114778 - 114778

Published: Oct. 30, 2023

Language: Английский

Citations

36