Molecules,
Journal Year:
2023,
Volume and Issue:
28(3), P. 1275 - 1275
Published: Jan. 28, 2023
Novel
1,8-naphthalimide-based
fluorescent
probes
NI-1
and
NI-2
were
designed
screened
for
use
as
chemosensors
detection
of
heavy
metal
ions.
Two
moieties,
methylpyridine
(NI-1)
hydroxyphenyl
(NI-2),
attached
via
piperazine
at
the
C-4
position
napthalimide
core
resulting
in
a
notable
effect
on
their
spectroscopic
properties.
are
pH
sensitive
show
an
increase
fluorescence
intensity
around
525
nm
(switch
"on")
acidic
environment,
with
pKa
values
4.98
2.91,
respectively.
Amongst
ions
only
Cu2+
Hg2+
had
significant
The
is
quenched
presence
either
or
which
attributed
to
formation
1:1
metal-ligand
complexes
binding
constants
3.6
×
105
3.9
104,
chemosensor
can
be
used
quantification
sub-micromolar
quantities,
linear
range
from
250
nM
4.0
μM
limit
1.5
10-8
M.
determination
2
10
μM,
8.8
Conversely,
behaves
like
typical
photoinduced
electron
transfer
(PET)
sensor
Here,
complex
(binding
constant
8.3
103)
turns
green
into
"on"
state.
showed
remarkable
selectivity
towards
ions,
allowing
concentration
over
1.3
25
4.1
10-7
Biosensors,
Journal Year:
2025,
Volume and Issue:
15(3), P. 188 - 188
Published: March 14, 2025
This
study
provides
a
comprehensive
analysis
of
the
complex
interaction
between
heavy
metals
(HMs)
and
gut
microbiota,
adopting
bidirectional
approach
that
explores
both
influence
HMs
on
microbiota
populations
potential
role
probiotics
in
modulating
these
changes.
By
examining
interconnected
aspects,
aims
to
offer
deeper
understanding
how
disrupt
microbial
balance
probiotic
interventions
may
mitigate
or
reverse
effects,
promoting
detoxification
processes
overall
health.
In
addition,
review
highlights
innovative
tools,
such
as
biosensors,
for
rapid,
precise,
non-invasive
detection
urine.
These
advanced
technologies
enable
real-time
monitoring
effectiveness
probiotic-based
interventions,
offering
critical
insights
into
their
elimination
from
body
improving
detoxification.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(3), P. 1275 - 1275
Published: Jan. 28, 2023
Novel
1,8-naphthalimide-based
fluorescent
probes
NI-1
and
NI-2
were
designed
screened
for
use
as
chemosensors
detection
of
heavy
metal
ions.
Two
moieties,
methylpyridine
(NI-1)
hydroxyphenyl
(NI-2),
attached
via
piperazine
at
the
C-4
position
napthalimide
core
resulting
in
a
notable
effect
on
their
spectroscopic
properties.
are
pH
sensitive
show
an
increase
fluorescence
intensity
around
525
nm
(switch
"on")
acidic
environment,
with
pKa
values
4.98
2.91,
respectively.
Amongst
ions
only
Cu2+
Hg2+
had
significant
The
is
quenched
presence
either
or
which
attributed
to
formation
1:1
metal-ligand
complexes
binding
constants
3.6
×
105
3.9
104,
chemosensor
can
be
used
quantification
sub-micromolar
quantities,
linear
range
from
250
nM
4.0
μM
limit
1.5
10-8
M.
determination
2
10
μM,
8.8
Conversely,
behaves
like
typical
photoinduced
electron
transfer
(PET)
sensor
Here,
complex
(binding
constant
8.3
103)
turns
green
into
"on"
state.
showed
remarkable
selectivity
towards
ions,
allowing
concentration
over
1.3
25
4.1
10-7
