Genosensors in healthcare DOI

Pooja Chugh,

Subodh Soni,

Manjeet Chahar

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 589 - 610

Published: Nov. 29, 2024

Language: Английский

Recent Progress in Functional-Nucleic-Acid-Based Fluorescent Fiber-Optic Evanescent Wave Biosensors DOI Creative Commons
Zheng Wang, Xinhui Lou

Biosensors, Journal Year: 2023, Volume and Issue: 13(4), P. 425 - 425

Published: March 27, 2023

Biosensors capable of onsite and continuous detection environmental food pollutants biomarkers are highly desired, but only a few sensing platforms meet the “2-SAR” requirements (sensitivity, specificity, affordability, automation, rapidity, reusability). A fiber optic evanescent wave (FOEW) sensor is an attractive type portable device that has advantages high sensitivity, low cost, good reusability, long-term stability. By utilizing functional nucleic acids (FNAs) such as aptamers, DNAzymes, rational designed acid probes specific recognition ligands, FOEW been demonstrated to be general platform for various targets ranging from small molecules heavy metal ions proteins, acids, pathogens. In this review, we cover progress fluorescent FNA-based biosensor since its first report in 1995. We focus on chemical modification optical mechanisms five above-mentioned types targets. The challenges prospects isolation high-quality reagent-free detection, stability under application conditions, throughput also included review highlight future trends development biosensors detection.

Language: Английский

Citations

8

Paper-based nucleic acid biosensors DOI
Ece Ekşin, Ayla Yildirim, Aysen Bozoglu

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2023, Volume and Issue: 171, P. 117511 - 117511

Published: Dec. 27, 2023

Language: Английский

Citations

7

Plasmonic Fluorescence Sensors in Diagnosis of Infectious Diseases DOI Creative Commons

Juiena Hasan,

Sangho Bok

Biosensors, Journal Year: 2024, Volume and Issue: 14(3), P. 130 - 130

Published: March 2, 2024

The increasing demand for rapid, cost-effective, and reliable diagnostic tools in personalized point-of-care medicine is driving scientists to enhance existing technology platforms develop new methods detecting measuring clinically significant biomarkers. Humanity confronted with growing risks from emerging recurring infectious diseases, including the influenza virus, dengue virus (DENV), human immunodeficiency (HIV), Ebola tuberculosis, cholera, and, most notably, SARS coronavirus-2 (SARS-CoV-2; COVID-19), among others. Timely diagnosis of infections effective disease control have always been paramount importance. Plasmonic-based biosensing holds potential address threat posed by diseases enabling prompt monitoring. In recent years, numerous plasmonic risen challenge offering on-site strategies complement traditional like polymerase chain reaction (PCR) enzyme-linked immunosorbent assays (ELISA). Disease detection can be accomplished through utilization diverse phenomena, such as propagating surface plasmon resonance (SPR), localized SPR (LSPR), surface-enhanced Raman scattering (SERS), fluorescence (SEF), infrared absorption spectroscopy, sensors. This review focuses on employing sensors, highlighting their pivotal role swift remarkable sensitivity. It underscores necessity continued research expand scope capabilities sensors field diagnostics.

Language: Английский

Citations

2

Selective and naked eye colorimetric detection of creatinine through aptamer-based target-induced passivation of gold nanoparticles DOI Creative Commons
Chiranjit Das,

Jeethu Raveendran,

Jagadeesh Bayry

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(46), P. 33784 - 33793

Published: Jan. 1, 2024

We report a simple naked eye colorimetric detection assay developed for creatinine using the surface passivation of gold nanoparticles (AuNPs)-creatinine binding aptamer conjugate in presence creatinine.

Language: Английский

Citations

2

A natural biomaterial promotes hybridization chain reaction for ultra-sensitive detection of miRNA-155 DOI
Yongjun Bian,

Mengwei Li,

Zhaojie Wu

et al.

Talanta, Journal Year: 2023, Volume and Issue: 266, P. 125117 - 125117

Published: Aug. 23, 2023

Language: Английский

Citations

5

Advances in Bioreceptor Layer Engineering in Nanomaterial‐based Sensing of Pseudomonas Aeruginosa and its Metabolites DOI
Lorico DS. Lapitan, Bren Mark B. Felisilda,

Cristina Tiangco

et al.

Chemistry - An Asian Journal, Journal Year: 2024, Volume and Issue: unknown

Published: May 23, 2024

Pseudomonas aeruginosa is a pathogen that infects wounds and burns causes severe infections in immunocompromised humans. The high virulence, the rise of antibiotic-resistant strains, easy transmissibility P. necessitate its fast detection control. gold standard for detecting aeruginosa, plate culture method, though reliable, takes several days to complete. Therefore, developing accurate, rapid, easy-to-use diagnostic tools highly desirable. Nanomaterial-based biosensors are at forefront secondary metabolites. This review summarises biorecognition elements, biomarkers, immobilisation strategies, current state-of-the-art aeruginosa. highlights underlying principles bioreceptor layer engineering design optical, electrochemical, mass-based, thermal based on nanomaterials. advantages disadvantages these their future point-of-care applications also discussed. outlines significant advancements sensors Research efforts have identified elements specific selective towards stability, ease preparation, cost-effectiveness, integration onto transducers pivotal application sensors. At same time, when clinically analytes such as virulence factors need be addressed, sensor's sensitivity, reliability, response time samples obtained from patients. applicability developed sensor may an added advantage since it enables onsite determination. In this context, optical methods offer promising potential.

Language: Английский

Citations

0

Genosensors in healthcare DOI

Pooja Chugh,

Subodh Soni,

Manjeet Chahar

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 589 - 610

Published: Nov. 29, 2024

Language: Английский

Citations

0