Photonic Crystal Enhanced Fluorescence: A Review on Design Strategies and Applications

Micromachines, Journal Year: 2023, Volume and Issue: 14(3), P. 668 - 668

Published: March 17, 2023

Nanoscale fluorescence emitters are efficient for measuring biomolecular interactions, but their utility applications requiring single-unit observations is constrained by the need large numerical aperture objectives, intermittency, and poor photon collection efficiency resulting from omnidirectional emission. Photonic crystal (PC) structures hold promise to address aforementioned challenges in enhancement. In this review, we provide a broad overview of PCs explaining structures, design strategies, fabrication techniques, sensing principles. Furthermore, discuss recent PC-enhanced fluorescence-based biosensors incorporated with emerging technologies, including nucleic acids sensing, protein detection, steroid monitoring. Finally, current associated an outlook enhancement photonic-plasmonics coupling point-of-care biosensing as well monitoring analytes biological environmental relevance. The review presents transdisciplinary arena spectroscopy photo-plasmonics, life science research, materials chemistry, cancer diagnostics, internet things.

Language: Английский

---

Graphene metasurface biosensor design for label-free peptide detection with machine learning optimization based on support vector regression with polynomial kernel

Diamond and Related Materials, Journal Year: 2025, Volume and Issue: unknown, P. 112053 - 112053

Published: Jan. 1, 2025

Language: Английский

---

Smartphone-Based Attomolar Cyanide Ion Sensing Using Au-Graphene Oxide Cryosoret Nanoassembly and Benzoxazolium-Based Fluorophore in a Surface Plasmon-Coupled Enhanced Fluorescence Interface

Langmuir, Journal Year: 2023, Volume and Issue: 39(22), P. 7939 - 7957

Published: May 25, 2023

Photoplasmonic platforms are being demonstrated as excellent means for bridging nanochemistry and biosensing approaches at advanced interfaces, thereby augmenting the sensitivity quantification of desired analytes. Although resonantly coupled electromagnetic waves surface plasmon-coupled emission (SPCE) interface investigated with myriad nanomaterials in order to boost detection limits, rhodamine moieties ubiquitously used SPCE reporter molecules spite their well-known limitations. In overcome this constraint, work, a benzoxazolium-based fluorescent molecule, (E)-2-(4-(dimethylamino)styryl)-3-methylbenzo[d]oxazol-3-ium iodide (DSBO), was synthesized selectively detect cyanide (CN-) ions water samples. To end, fabricated substrates is tested spacer, cavity, extended cavity nanointerfaces rationalize configurational robustness. The performance sensor further improved careful engineering gold (Au)-graphene oxide (GO) cryosoret nanoassemblies via an adiabatic cooling technology. unique dequenching (turn-on) quenched (turn-off) signal hybridized metal-π plasmon synergistic coupling nanovoids nanocavities assisting delocalized Bragg localized Mie plasmons. spectro-plasmonic analysis yielded highly directional, polarized (>95%), enhanced attributes attomolar limit 10 aM CN- high linearity (R2 = 0.996) reliability, addition exceptional correlation theoretically obtained TFclac simulations. ion sensing experimentally validated smartphone-based cost-effective technology render device amenable resource-limited settings. We believe that fluorophore-cryosoret nanoassemblage presented here encourages development frugal, unconventional, desirable strategies selective quantitation environmentally physiologically relevant analytes trace concentrations use point-of-care diagnostics.

Language: Английский

---

Review of Gold Nanoparticles in Surface Plasmon-Coupled Emission Technology: Effect of Shape, Hollow Nanostructures, Nano-Assembly, Metal–Dielectric and Heterometallic Nanohybrids

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(1), P. 111 - 111

Published: Jan. 2, 2024

Point-of-care (POC) diagnostic platforms are globally employed in modern smart technologies to detect events or changes the analyte concentration and provide qualitative quantitative information biosensing. Surface plasmon-coupled emission (SPCE) technology has emerged as an effective POC tool for developing robust biosensing frameworks. The simplicity, robustness relevance of attracted researchers physical, chemical biological milieu on account its unique attributes such high specificity, sensitivity, low background noise, highly polarized, sharply directional, excellent spectral resolution capabilities. In past decade, numerous nano-fabrication methods have been developed augmenting performance conventional SPCE technology. Among them utility plasmonic gold nanoparticles (AuNPs) enabled demonstration plethora reliable platforms. Here, we review nano-engineering applications AuNPs based shape, hollow morphology, metal–dielectric, nano-assembly heterometallic nanohybrids under optical well competencies. current emphasizes recent evaluates latest advancements field comprehend futuristic scope perspectives exploiting Au nano-antennas hotspot generation

Language: Английский

---

Advancements in wearable sensors for cardiovascular disease detection for health monitoring

Materials Science and Engineering R Reports, Journal Year: 2024, Volume and Issue: 159, P. 100804 - 100804

Published: May 21, 2024

Language: Английский

---

Luminescent Guests Encapsulated in Metal–Organic Frameworks for Portable Fluorescence Sensor and Visual Detection Applications: A Review

Biosensors, Journal Year: 2023, Volume and Issue: 13(4), P. 435 - 435

Published: March 29, 2023

Metal–organic frameworks (MOFs) have excellent applicability in several fields and significant structural advantages, due to their open pore structure, high porosity, large specific surface area, easily modifiable functionalized porous surface. In addition, a variety of luminescent guest (LG) species can be encapsulated the pores MOFs, giving MOFs broader capability. The applications LG@MOF sensors, constructed by doping with LGs such as lanthanide ions, carbon quantum dots, complexes, organic dyes, metal nanoclusters, for fluorescence detection various target analyses biomarkers, pesticides, preservatives are systematically introduced this review. development these sensors portable visual sensing is then covered. Finally, challenges that sectors currently face, well potential future growth, briefly discussed.

Language: Английский

---

Strategies to improve performances of fluorescent biosensors based on smartphones: Sensitivity, high throughput, and smart detection

Sensors and Actuators A Physical, Journal Year: 2024, Volume and Issue: 368, P. 115120 - 115120

Published: Feb. 7, 2024

Language: Английский

---

Optical coupling of bio-inspired mustard protein-based bimetallic nanohybrids with propagating surface plasmon polaritons for femtomolar nitrite ion sensing: Cellphone-based portable detection device

Nano-Structures & Nano-Objects, Journal Year: 2023, Volume and Issue: 35, P. 101025 - 101025

Published: July 1, 2023

Language: Английский

---

Principles and Applications of Resonance Energy Transfer Involving Noble Metallic Nanoparticles

Materials, Journal Year: 2023, Volume and Issue: 16(8), P. 3083 - 3083

Published: April 13, 2023

Over the past several years, resonance energy transfer involving noble metallic nanoparticles has received considerable attention. The aim of this review is to cover advances in transfer, widely exploited biological structures and dynamics. Due presence surface plasmons, strong plasmon absorption local electric field enhancement are generated near nanoparticles, resulting shows potential applications microlasers, quantum information storage devices micro-/nanoprocessing. In review, we present basic principle characteristics as well representative progress such fluorescence nanometal plasmon-induced metal-enhanced fluorescence, surface-enhanced Raman scattering cascade transfer. We end with an outlook on development process. This will offer theoretical guidance for further optical methods distance distribution analysis microscopic detection.

Language: Английский

---

Plasmonic Biosensors in Cancer-Associated miRNA Detection

Biosensors, Journal Year: 2025, Volume and Issue: 15(3), P. 165 - 165

Published: March 4, 2025

Cancer is one of the most lethal diseases and has distinct variants that affect over 60 organs in human body. The necessity advanced methodologies for early diagnosis cancer grown past decades. Among various biomarkers, microRNAs (miRNAs) have emerged as highly specific minimally invasive indicators detection, prognosis, treatment monitoring. Their stability biological fluids their critical role gene regulation make them valuable targets diagnostic applications. Plasmonic biosensors gained massive attention owing to unique optical properties, such surface plasmon resonance, making promising tools sensitive selective analysis cancer-associated biomarkers. In contrast previous reviews, this work offers a comprehensive overview advancements from approximately five years, particularly detection miRNAs. It emphasizes emerging plasmonic sensing strategies, integration with novel nanomaterials, enhanced signal amplification techniques. By focusing on these recent innovations, review provides new insights into potential improve treatment.

Language: Английский

---