Development of CuO Nanoparticles from the Mucus of Garden Snail Cornu aspersum as New Antimicrobial Agents DOI Creative Commons

Pavlina Dolashka,

Karina Marinova,

Petar D. Petrov

et al.

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(4), P. 506 - 506

Published: April 15, 2024

Several biologically active compounds involved in the green synthesis of silver and gold nanoparticles have been isolated from snail mucus characterized. This paper presents a successful method for application Cornu aspersum as bioreducing agent copper sulfate biostabilizer oxide (CuONPs-Muc) obtained. The at room temperature neutral pH yielded with spherical shape an average diameter 150 nm. structure properties CuONPs-Muc were characterized using various methods techniques, such ultraviolet–visible spectroscopy (UV–vis), high-performance liquid chromatography (HPLC), one-dimensional polyacrylamide gel electrophoresis (1D-PAGE), up-conversion infrared Fourier transform (FTIR), scanning electron microscopy combined energy dispersive (SEM/EDS), Raman imaging, thermogravimetric analysis (TG-DSC), etc. Mucus proteins molecular weights 30.691 kDa 26.549 identified, which are biogenic production CuONPs-Muc. macromolecular shell formed around ions contributes to higher efficiency synthesized inhibiting bacterial growth several Gram-positive (Bacillus subtilis NBIMCC2353, Bacillus spizizenii ATCC 6633, Staphylococcus aureus 6538, Listeria innocua NBIMCC8755) Gram-negative (Escherichia coli ATCC8739, Salmonella enteitidis NBIMCC8691, typhimurium 14028, Stenotrophomonas maltophilia 17666) bacteria compared baseline mucus. bioorganic presented here provides highly pronounced antimicrobial effect. These results will expand knowledge field natural nanomaterials their role emerging dosage forms.

Language: Английский

Nanoengineered Copper: Revolutionizing Breast Cancer Care DOI Open Access
Sudip Mandal

International Journal of Scientific Research in Science Engineering and Technology, Journal Year: 2025, Volume and Issue: 12(1), P. 164 - 180

Published: Feb. 3, 2025

Breast cancer continues to rank as a predominant cause of illness and death among women globally, emphasizing the critical need for innovative effective treatment approaches. Traditional methods such chemotherapy, surgery, radiation therapy often face limitations, including toxicity, resistance, non-specific targeting. In recent years, advancements in nanotechnology have brought about transformative solutions, with nanoengineered copper emerging frontrunner. Nanoengineered copper’s unique properties- its catalytic capabilities, biocompatibility, potential surface modification- offer unprecedented opportunities revolutionize breast care. These nanoparticles not only enable precise targeting cells but also improve diagnostic accuracy through advanced imaging techniques. Furthermore, their application photothermal photodynamic therapies provides dual approach destroying while minimizing harm healthy tissues. With ability modulate tumor microenvironment act platform combination therapies, holds immense promise both early detection treatment. This article explores wide-ranging applications copper, from innovations therapeutic breakthroughs, underscoring redefine management patient outcomes.

Language: Английский

Citations

0

Green Synthesis of Copper Nanoparticles using Rosmarinus officinalis L. Extract Improves the Developmental Competence of Mouse Oocytes during in Vitro Maturation DOI

Parisa Bagheshzadeh,

Elaheh Amini, Farzaneh Baniasadi

et al.

Reproductive Sciences, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 19, 2025

Language: Английский

Citations

0

Phytofabrication of copper nanoparticles using Momordica cymbalaria fruit extract and their antibacterial, antioxidant and anti-inflammatory properties DOI Creative Commons
Shazia Parveen, Khateef Riazunnisa

Hybrid Advances, Journal Year: 2025, Volume and Issue: unknown, P. 100421 - 100421

Published: Feb. 1, 2025

Language: Английский

Citations

0

Green Synthesis of Copper Nanoparticles Using a Bioflocculant from Proteus mirabilis AB 932526.1 for Wastewater Treatment and Antimicrobial Applications DOI Creative Commons

Nkanyiso C. Nkosi,

Albertus K. Basson, Zuzingcebo G. Ntombela

et al.

Applied Nano, Journal Year: 2025, Volume and Issue: 6(1), P. 5 - 5

Published: March 3, 2025

Nanotechnology offers effective solutions for removing contaminants and harmful bacteria from polluted water. This study synthesized copper nanoparticles using a carbohydrate-based bioflocculant derived Proteus mirabilis AB 932526.1. The is natural polymer that facilitates the aggregation of particles, enhancing efficiency nanoparticle synthesis process. Characterization was conducted Fourier Transform Infrared Spectroscopy, Scanning Electron Microscopy, Energy-Dispersive X-ray Ultraviolet-Visible Diffraction, Transmission Microscopy techniques to assess their properties, flocculation efficiency, antibacterial characteristics. optimal 80% achieved at concentration 0.4 mg/mL, while 1 mg/mL resulted in lower 60%. effects biosynthesized on human-derived embryonic renal cell cultures were also investigated, demonstrating they are safe concentrations. effectively removed staining dyes such as safranin (90%), carbol fuchsine (88%), methylene blue (91%), methyl orange (93%), Congo red (94%), compared blank showing only 39% removal. Furthermore, when both chemical flocculants bioflocculants, exhibited significant nutrient removal efficiencies nitrogen, sulfur, phosphate, total nitrates coal mine Vulindlela domestic wastewater. Notably, these demonstrated exceptional activity against Gram-positive Gram-negative bacteria.

Language: Английский

Citations

0

Effects of reaction composition on the physicochemical and antimicrobial properties of copper-based nanoparticles fabricated via precipitation reaction DOI
Alireza Ebrahiminezhad, S. Sohrabi,

Mohammad Javad Kargar

et al.

Journal of materials research/Pratt's guide to venture capital sources, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

Language: Английский

Citations

0

Effects of seaweed-​mediated copper nanoparticles on antibacterial activity and survival rate of Guppy ornamental fish DOI Creative Commons

Nagubandi Lakshmi Anvitha,

Krishnamoorthy Santhosh,

Kannan Kamala

et al.

North American Journal of Aquaculture, Journal Year: 2025, Volume and Issue: unknown

Published: March 20, 2025

Abstract Objective The purpose of this study was to develop ecofriendly and sustainable copper nanoparticles (CuNPs) using Padina pavonica extract. CuNPs were characterized scanning electron microscopy (SEM) for morphological analysis, energy dispersive X-ray (EDS) spectroscopy elemental composition, Fourier transform infrared (FTIR) functional group identification, UV-visible optical properties. We evaluated the toxicity survival rates Guppy Poecilia reticulata larvae that subjected varied CuNP concentrations determine best concentration range future aquaculture uses. Methods different characterization stability synthesized investigated SEM, EDS, FTIR, spectroscopy. To evaluate safe exposure levels, exposed monitored over a 72-hour period. Results biosynthesized exhibited characteristic surface plasmon resonance peaks at 260 nm, confirming their formation, with FTIR revealing involvement groups like O-H O-SO3H in nanoparticle capping. SEM analysis showed irregular, aggregated CuNPs, sizes ranging from 50 200 nm. Energy confirmed including copper, oxygen, chlorine, carbon. Conclusions This article describes environmentally acceptable method manufacturing extract as natural reducing agent. established an appropriate by comparing concentrations. findings provide important insights into use aquaculture, which benefits both aquatic organism health environmental sustainability.

Language: Английский

Citations

0

Sustainable Antimicrobial and Anticancer Agents: Eco‐Friendly Synthesis of Copper Nanoparticles Using Biebersteinia multifida DC DOI
Kovan Dilawer Issa, Hazha Omar Othman, Hawraz Ibrahim M. Amin

et al.

Chemistry & Biodiversity, Journal Year: 2025, Volume and Issue: unknown

Published: April 22, 2025

ABSTRACT Biebersteinia multifida DC. is a wild therapeutic plant, traditionally used for various medicinal applications. The aim of the present study to extract bioactive constituents from plants' roots and synthesize copper nanoparticles (CuNPs). Ethanolic extraction plant's yielded 19 compounds, recognized through gas chromatography–mass spectroscopy (GC‐MS), mainly including citraconic anhydride, γ‐sitosterol, 2‐furancarboxaldehyde. prepared CuNPs have been fully characterized. biological activity evaluations revealed these possess acceptable antibacterial antifungal activities. Furthermore, displayed significant cytotoxic potency toward “4T1 breast cancer cells” while showing relatively low cell death rate against normal “HEK‐293 kidney cell”. In conclusion, our findings showed that can be synthesized B . with simple, fast, eco‐friendly procedure. These are efficient in antimicrobial anticancer

Language: Английский

Citations

0

The Potency of Noni Leaves Extract (Morinda citrifolia L.) as a Bioreductor in the Synthesis of Copper Nanoparticles and Its Effectiveness as an Antibacterial against Streptococcus pyogenes DOI Creative Commons

Retno Wahdany Huda Putri,

Suyatno Sutoyo

Jurnal Kimia Sains dan Aplikasi, Journal Year: 2025, Volume and Issue: 28(3), P. 138 - 145

Published: March 26, 2025

The noni (Morinda citrifolia L) is one of Indonesia’s traditional medicinal plants, which people have widely used to treat dysentery, hypertension, diabetes, and heart attacks prevent cancer. contains phenolic compounds, namely flavonoids, anthraquinones, alkaloids, tannins, the potential act as bioreductors. research aims synthesize copper nanoparticles (CuNPs) using leaves extract a bioreductor assay their antibacterial activity. CuNPs were synthesized by mixing leaf sulfate in 1:1, 1:2, 1:3, 1:4 ratio. It was characterized UV-Vis, PSA, FTIR, XRD. Antibacterial activity tested disc diffusion method on Streptococcus pyogenes. results showed that optimum synthesis at ratio 1:3 pH 10. had maximum UV-Vis absorption wavelength 305 nm, an average particle size 5.46 nm with polydispersity index (PDI) 0.2048, Cu-O peak observed 560 cm-1 FTIR spectrum. XRD measurements revealed peaks 2θ angles 43.38°, 50.50°, 74.43°. good agent against pyogenes inhibition zone diameter 17.3 mm. Thus, be developed for

Language: Английский

Citations

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Enhanced Structural, Optical, Electrical, and Dielectric Properties of PVA/Cu Nanocomposites for Potential Applications in Flexible Electronics DOI Open Access
Miguel Hernández, Carlos Roberto Ascencio-Hurtado, Filiberto Candia García

et al.

Materials, Journal Year: 2025, Volume and Issue: 18(9), P. 2087 - 2087

Published: May 2, 2025

Copper (Cu) nanoparticles, known for their high electrical conductivity and cost-effectiveness, have emerged as essential materials in various applications from flexible electronics to antimicrobial agents. This work focuses on the synthesis characterization of semiconductive nanostructured films composed polyvinyl alcohol (PVA) with embedded Cu nanoparticles. The study provides a comprehensive analysis structural, optical, electrical, dielectric properties resulting nanocomposites. results indicate significant reduction optical band gap, 4.82 eV pure PVA 2.6–2.8 nanocomposites, alongside enhanced conductivities reaching 1.20 S/cm 5 wt.% Cu. Dielectric assessments further reveal constants, underscoring potential these electronic applications. highlights effectiveness incorporating nanoparticles into polymer matrices, paving way advanced that meet demands next-generation electronics.

Language: Английский

Citations

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Green Synthesis of Antibacterial CuO Nanoparticles Based on the Synergy Between Cornu aspersum Snail Mucus and Ascorbic Acid DOI Creative Commons

Maria Todorova,

Angelina Kosateva,

Ventsislava Yankova Petrova

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(2), P. 291 - 291

Published: Jan. 13, 2025

Many biologically active compounds have been identified in the mucus of garden snail Cornu aspersum, which are effective treatment several diseases such as cancer, ulcers, wounds, etc. The incorporation these into green synthesis copper nanoparticles (CuONPs-Muc) was demonstrated our previous study. Based on synergistic effect two reducing agents—C. aspersum and ascorbic acid (AsA)—on CuSO4.5H2O, also act stabilizers resulting compound, a new method for “green” CuONPs-Muc is presented. Using agents has advantages, forming spherical with diameter about 150 nm formation time to 3 h. Analyses by ultraviolet–visible spectroscopy (UV-Vis) Fourier transform infrared (FT-IR) show CuONPs-Muc, composed mixture oxide. This confirmed scanning electron microscopy combined energy-dispersive (SEM/EDS) X-ray diffraction (XRD). Another important advantage CuONPs obtained stronger inhibitory bacterial growth some Gram-positive Gram-negative strains, compared prepared only one agent, i.e., fraction an MW > 20 kDa.

Language: Английский

Citations

0