International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(3), P. 1263 - 1263
Published: Jan. 31, 2025
The emergence of SARS-CoV-2 variants has significantly impacted the global response to COVID-19 pandemic. This review examines genetic diversity variants, their roles in epidemiological tracking, and influence on viral fitness. Variants concern (VOCs) such as Alpha, Beta, Gamma, Delta, Omicron have demonstrated increased transmissibility, altered pathogenicity, potential resistance neutralizing antibodies. Epidemiological tracking these is crucial for understanding spread, informing public health interventions, guiding vaccine development. also explores how specific mutations spike protein other genomic regions contribute fitness, affecting replication efficiency, immune escape, transmission dynamics. By integrating surveillance data with clinical findings, this provides a comprehensive overview ongoing evolution its implications strategies new
Language: Английский