Chicken caecal enterotypes in indigenous Kadaknath and commercial Cobb chicken lines are associated with Campylobacter abundance and influenced by farming practices
Frontiers in Microbiomes,
Journal Year:
2023,
Volume and Issue:
2
Published: Dec. 4, 2023
Identifying
farming
practices
that
decrease
susceptibility
to
infectious
diseases
and
optimise
food
conversion
efficiency
is
valuable
for
chicken
welfare
productivity,
the
environment,
public
health.
Enterotypes
can
be
used
define
microbial
community
phenotypes
have
differential,
potentially
significant
impacts
on
gut
In
this
study,
we
delineated
enterotypes
by
analysing
microbiomes
of
300
indigenous
Kadaknath
commercial
Cobb400
broiler
chickens
raised
across
60
farms
in
western
India.
Using
a
compositional
data
approach,
identified
three
distinct
enterotypes:
PA1
(n=290),
PA2
(n=142)
PA3
(n=67).
clustered
more
closely
with
each
other
than
PA3,
however,
had
significantly
lower
alpha
diversity
PA1.
high
Firmicutes:
Bacteroides
ratio,
was
dominated
Faecalibacterium
higher
abundance
Prevotellamassilia
enterotypes.
characterised
its
low
diversity,
common
taxa
Phascolarctobacterium
A
Phocaeicola
dorei
Campylobacter
highest
Bacteroidota
defined
prevalence
such
as
CAG-831
Mucispirillum
schaedleri
.
Network
analysis
showed
all
different
proportions
competing
Firmicutes-dominant
Bacteroidota-dominant
guilds.
Random
Forest
Modelling
using
farm
characteristics
predictive
enterotype.
Factors
affecting
enterotype
include
whether
were
open,
enclosed
or
caged,
location
farms,
visitors
allowed
inside,
number
people
contact
chickens,
line,
presence
dogs
flock
thinning
took
place.
This
study
suggests
are
influenced
practices,
hence
modification
could
reduce
burden
zoonotic
pathogens
Language: Английский
Animal and In Vitro Models as Powerful Tools to Decipher the Effects of Enteric Pathogens on the Human Gut Microbiota
Microorganisms,
Journal Year:
2023,
Volume and Issue:
12(1), P. 67 - 67
Published: Dec. 29, 2023
Examining
the
interplay
between
intestinal
pathogens
and
gut
microbiota
is
crucial
to
fully
comprehend
pathogenic
role
of
enteropathogens
their
broader
impact
on
human
health.
Valid
alternatives
studies
have
been
introduced
in
laboratory
practice
evaluate
effects
infectious
agents
microbiota,
thereby
exploring
translational
implications
functionality
overall
Different
animal
species
are
currently
used
as
valuable
models
for
infections.
In
addition,
considering
recent
advances
bioengineering,
futuristic
vitro
resembling
environment
also
available
this
purpose.
review,
main
(i.e.,
Clostridioides
difficile,
Campylobacter
jejuni,
diarrheagenic
Escherichia
coli,
non-typhoidal
Salmonella
enterica,
Shigella
flexneri
sonnei,
Vibrio
cholerae,
Bacillus
cereus)
microbial
communities
summarized,
with
specific
emphasis
results
derived
from
investigations
employing
models.
Language: Английский
Campylobacteriosis: A rising threat in foodborne illnesses
Open Veterinary Journal,
Journal Year:
2024,
Volume and Issue:
14(8), P. 1733 - 1733
Published: Jan. 1, 2024
Campylobacteriosis
is
a
foodborne
illness
that
contracted
by
eating
contaminated
food,
particularly
animal
products
like
meat
from
diseased
animals
or
corpses
tainted
with
harmful
germs.
The
epidemiology
of
campylobacteriosis
varies
significantly
between
low-,
middle-,
and
high-income
countries.
Campylobacter
has
complicated
poorly
known
survival
strategy
for
getting
past
host
barriers
causing
sickness
in
humans.
adaptability
to
unfavorable
environments
the
host’s
immune
system
seems
be
one
most
crucial
elements
intestinal
colonization.
A
infection
may
result
fever,
nausea,
vomiting,
mild
severe
bloody
diarrhea
Effective
rapid
diagnosis
species
infections
hosts
essential
both
individual
treatment
disease
management
at
farm
level.
According
recent
meta-analysis
research,
main
risk
factor
travel,
which
followed
undercooked
chicken,
being
exposed
environment,
coming
into
close
contact
livestock.
jejuni,
occasionally
coli,
are
primary
causes
gastroenteritis,
significant
humans
public
health.
best
antibiotic
medications
eradicating
decreasing
feces
erythromycin,
clarithromycin,
azithromycin.
reduce
number
human
caused
restrict
amount
contamination
poultry
flock
its
products,
even
if
majority
through
handling
ingestion
chicken.
Language: Английский
The Interactive Effects of Nutrient Density and Breed on Growth Performance and Gut Microbiota in Broilers
Meiting Jia,
No information about this author
Jiaqi Lei,
No information about this author
Yuanyang Dong
No information about this author
et al.
Animals,
Journal Year:
2024,
Volume and Issue:
14(23), P. 3528 - 3528
Published: Dec. 6, 2024
This
study
investigated
whether
variations
in
growth
response
to
low
nutrient
density
across
breeds
are
linked
microbiota
regulation.
Arbor
Acres
(
Language: Английский
Fecal Microbiota Transplantation Reduces Campylobacter jejuni Colonization in Young Broiler Chickens Challenged by Oral Gavage but Not by Seeder Birds
Antibiotics,
Journal Year:
2023,
Volume and Issue:
12(10), P. 1503 - 1503
Published: Oct. 2, 2023
Campylobacter
spp.,
particularly
C.
jejuni
and
coli,
are
major
food
safety
concerns,
transmitted
to
humans
mainly
via
contaminated
poultry
meat.
In
a
previous
study,
we
found
that
some
commercial
broiler
farms
consistently
produced
Campylobacter-free
flocks
while
others
reared
Campylobacter-colonized
flocks,
significant
differences
in
the
gut
microbiota
compositions
between
two
types
of
farm
categories
were
revealed.
Therefore,
hypothesized
influences
colonization
from
may
confer
resistance
chicken
intestine.
this
fecal
transplantation
(FMT)
trials
performed
test
hypothesis.
Newly
hatched
chicks
given
FMT
oral
gavage
cecal
content
adult
chickens
(treatment
groups)
or
PBS
(control
before
feed
consumption.
Approximately
weeks
after
FMT,
birds
challenged
with
either
by
(trial
1)
co-mingling
seeder
2)
evaluate
potential
protective
effect
FMT.
Cecal
contents
collected
(3
times,
5
days
apart)
determine
levels
culture
16S
rRNA
gene
sequencing.
reduced
significantly
(log10
1.2–2.54
CFU/g)
trial
1
but
not
2,
although
impacted
diversity
both
trials.
Several
genera,
such
as
Butyricimonas,
Parabacteroides,
Parasutterella,
Bilophila,
Fournierella,
Phascolarctobacterium,
Helicobacter,
had
increased
abundance
FMT-treated
groups
Furthermore,
was
be
negatively
correlated
Escherichia
Ruminococcus_torques_group
genera.
These
findings
indicate
even
though
can
positively
affect
subsequent
development
young
broilers,
its
inhibitory
on
varies
appears
influenced
challenge
models.
Language: Английский
No colonization resistance to Campylobacter jejuni in broilers fed brown algal extract-supplemented diets
Eliška Eliasson,
No information about this author
Li Sun,
No information about this author
Gunnar Cervin
No information about this author
et al.
Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
15
Published: June 27, 2024
gastroenteritis
is
the
most
commonly
reported
zoonosis
within
EU,
with
poultry
products
regarded
as
primary
source
of
transmission
to
humans.
Therefore,
finding
strategies
reduce
Language: Английский
Influence of gut microbiota on Campylobacter colonization and antimicrobial resistance development in the chicken host
Published: Jan. 1, 2023
Campylobacter,
predominantly
Campylobacter
jejuni,
is
a
global
foodborne
and
zoonotic
pathogen
responsible
for
significant
portion
of
the
gastroenteritis
diarrheal
illness
in
humans
worldwide.
Antibiotic-resistant
also
recognized
as
serious
threat
to
public
health
because
it
limits
treatment
options
increases
severity
infections.
Contaminated
poultry
meat
has
been
identified
most
common
source
infection
many
countries,
including
United
States.
Therefore,
effective
control
at
farm
level
would
greatly
reduce
spread
through
food
supply
chain.
In
this
project,
we
deciphered
association
between
colonization
gut
microbiota
composition
commercial
broilers.
We
evaluated
efficacy
using
fecal
transplantation
(FMT)
potential
method
reducing
Additionally,
assessed
impact
treating
broilers
with
enrofloxacin
(ENRO)
on
metabolic
processes.
The
key
findings
project
can
be
summarized
follows.
1)
Significant
differences
microbial
diversity
were
observed
cecal
structure
Campylobacter-negative
Campylobacter-positive
broiler
flocks
over
multiple
production
cycles.
2)
FMT
reduced
significantly
when
challenge
was
given
individual
birds
via
oral
gavage,
but
not
done
horizontally
by
use
seeder
birds.
3)
ENRO
initially
quickly
selected
fluoroquinolone
(FQ)-resistant
mutants
treated
4)
Both
treatments
altered
significantly;
additionally,
had
substantial
metabolism.
conclusion,
these
results
showed
that
differed
based
their
status
under
settings
could
substantially
influence
development
FQ-resistance
chicken
intestine
laboratory
conditions.
These
provide
valuable
insights
developing
microbiota-based
approaches
may
used
mitigate
broilers,
thereby
enhancing
safety
transmission
from
humans.
Language: Английский