Seasonal Change in Microbial Diversity: Bile Microbiota and Antibiotics Resistance in Patients with Bilio-Pancreatic Tumors: A Retrospective Monocentric Study (2010–2020) DOI Creative Commons
Paola Di Carlo, Nicola Serra, Consolato Sergi

et al.

Antibiotics, Journal Year: 2025, Volume and Issue: 14(3), P. 283 - 283

Published: March 9, 2025

Background: Bilio-pancreatic tumors are a severe form of cancer with high rate associated mortality. These patients showed the presence bacteria such as Escherichia coli and Pseudomonas spp. in bile-pancreatic tract. Therefore, efficient antibiotic therapy is essential to reduce bacterial resistance adverse events patients. Recent studies on seasonality infectious diseases may aid developing effective preventive measures. This study examines seasonal impact bile microbiota composition its microorganisms hepato-pancreatic-biliary cancer. Methods: We retrospectively evaluated effect seasonally from 149 strains isolated by 90 Italian positive culture samples collected through endoscopic retrograde cholangiopancreatography between 2010 2020. Results: Across all seasons, most frequently found were E. coli, spp., Enterococcus Regarding resistance, highest 3GC, fluoroquinolones, aminoglycosides, fosfomycin, piperacillin-tazobactam summer lowest spring, except for carbapenems colistin. Conclusions: Antibiotic has negative effects who rely antibiotics prevent treat infections. Knowing whether fungal changes seasons key information define adequate more therapy.

Language: Английский

Seasonal Change in Microbial Diversity: Bile Microbiota and Antibiotics Resistance in Patients with Bilio-Pancreatic Tumors: A Retrospective Monocentric Study (2010–2020) DOI Creative Commons
Paola Di Carlo, Nicola Serra, Consolato Sergi

et al.

Antibiotics, Journal Year: 2025, Volume and Issue: 14(3), P. 283 - 283

Published: March 9, 2025

Background: Bilio-pancreatic tumors are a severe form of cancer with high rate associated mortality. These patients showed the presence bacteria such as Escherichia coli and Pseudomonas spp. in bile-pancreatic tract. Therefore, efficient antibiotic therapy is essential to reduce bacterial resistance adverse events patients. Recent studies on seasonality infectious diseases may aid developing effective preventive measures. This study examines seasonal impact bile microbiota composition its microorganisms hepato-pancreatic-biliary cancer. Methods: We retrospectively evaluated effect seasonally from 149 strains isolated by 90 Italian positive culture samples collected through endoscopic retrograde cholangiopancreatography between 2010 2020. Results: Across all seasons, most frequently found were E. coli, spp., Enterococcus Regarding resistance, highest 3GC, fluoroquinolones, aminoglycosides, fosfomycin, piperacillin-tazobactam summer lowest spring, except for carbapenems colistin. Conclusions: Antibiotic has negative effects who rely antibiotics prevent treat infections. Knowing whether fungal changes seasons key information define adequate more therapy.

Language: Английский

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