
New Biotechnology, Journal Year: 2025, Volume and Issue: unknown
Published: May 1, 2025
The emergence of antibiotic-resistant pathogens has raised significant concerns in the poultry industry, driving search for alternatives to antibiotics as growth promoters animal feed. Probiotics, particularly those belonging Lactic Acid Bacteria (LAB) group, represent a promising solution by mitigating risk infectious disease. However, uniform concentration probiotic LAB is not suitable feed additives due varying kinetics. Additionally, genomic and physiological profiles strains involved must be thoroughly evaluated. In this study, we provide an analytical framework comprehensively assess potential antibiotic farming. Three - Pediococcus pentosaceus (isolated from corn silage), Ligilactobacillus salivarius (from gut) Lactococcus lactis gut rainbow trout) were sequenced characterized, with focus on evaluating their safety at level. analyses included co-culturing pathogens, assessing viable cells, determining minimum inhibitory bacteriocin-like substances (BLIS). addition demonstrating effective antimicrobial activity against avian (Salmonella spp., Clostridium spp. Campylobacter coli), results revealed notable traits all three strains, such tolerance bile salts acidic environment adhesion intestinal cells. conclusion, our highlighted tested biotechnological tools developing zootechnical additives. These probiotics show promise enhancing health productivity.
Language: Английский