Age-related oral microbiota dysbiosis and systemic diseases DOI Creative Commons
Ling Deng, Guangzhao Guan, Richard D. Cannon

et al.

Microbial Pathogenesis, Journal Year: 2025, Volume and Issue: 205, P. 107717 - 107717

Published: May 20, 2025

The oral microbiota is an essential microbial community within the human body, playing a vital role in maintaining health. In older adults, age-related changes are linked to both systemic and health impairments. use of various medications for diseases elderly can also contribute development diseases. Oral dysbiosis refers imbalance composition communities. This imbalance, along with disruptions host immune response prolonged inflammation, closely associated onset progression several It contributes conditions such as dental caries, periodontal disease, halitosis. diseases, including Alzheimer's type 2 diabetes mellitus, rheumatoid arthritis, atherosclerotic cardiovascular aspiration pneumonia. review aims explore how influences specific outcomes individuals, focusing on holds promise diagnostic tool, therapeutic target, prognostic biomarker managing metabolic infectious autoimmune Emphasizing proper care instilling understanding drugs prescribed disease impact microbiome, anticipated emerge key strategy promoting general adults.

Language: Английский

Age-related oral microbiota dysbiosis and systemic diseases DOI Creative Commons
Ling Deng, Guangzhao Guan, Richard D. Cannon

et al.

Microbial Pathogenesis, Journal Year: 2025, Volume and Issue: 205, P. 107717 - 107717

Published: May 20, 2025

The oral microbiota is an essential microbial community within the human body, playing a vital role in maintaining health. In older adults, age-related changes are linked to both systemic and health impairments. use of various medications for diseases elderly can also contribute development diseases. Oral dysbiosis refers imbalance composition communities. This imbalance, along with disruptions host immune response prolonged inflammation, closely associated onset progression several It contributes conditions such as dental caries, periodontal disease, halitosis. diseases, including Alzheimer's type 2 diabetes mellitus, rheumatoid arthritis, atherosclerotic cardiovascular aspiration pneumonia. review aims explore how influences specific outcomes individuals, focusing on holds promise diagnostic tool, therapeutic target, prognostic biomarker managing metabolic infectious autoimmune Emphasizing proper care instilling understanding drugs prescribed disease impact microbiome, anticipated emerge key strategy promoting general adults.

Language: Английский

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