Gastrointestinal disorders in post-COVID syndrome. Clinical guidelines DOI Creative Commons
В. Б. Гриневич, Л. Б. Лазебник, Yu. A. Kravchuk

et al.

Experimental and Clinical Gastroenterology, Journal Year: 2023, Volume and Issue: 12, P. 4 - 68

Published: May 20, 2023

Summary Post- COVID syndrome refers to the long-term consequences of a new coronavirus infection COVID-19, which includes set symptoms that develop or persist after COVID-19. Symptoms gastrointestinal disorders in post- syndrome, due chronic infl ammation, organ damage, prolonged hospitalization, social isolation, and other causes, can be persistent require multidisciplinary approach. The presented clinical practice guidelines consider main preventive therapeutic diagnostic approaches management patients with gastroenterological manifestations postCOVID syndrome. Guidelines were approved by 17th National Congress Internal Medicine 25th Gastroenterological Scientifi c Society Russia.

Language: Английский

Neuropsychiatric disorders in the course to SARS-CoV-2 virus infection, including biological pathomechanisms, psychosocial factors and long COVID-19 associated with “brain fog” DOI
Jakub Sadowski,

Samanta Anna Ostrowska,

Tomasz Klaudel

et al.

Journal of NeuroVirology, Journal Year: 2025, Volume and Issue: unknown

Published: April 7, 2025

Language: Английский

Citations

0

CURRENT CONCEPTS IN LONG-COVID BRAIN FOG AND POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME DOI
Jinny Tavee

Annals of Allergy Asthma & Immunology, Journal Year: 2024, Volume and Issue: 133(5), P. 522 - 530

Published: Aug. 23, 2024

Language: Английский

Citations

3

Impact of the Renin-Angiotensin System on the Pathogeny and Pharmacotherapeutics of Neurodegenerative Diseases DOI Creative Commons
Walther Bild, Alexandru Vasincu, Răzvan-Nicolae Rusu

et al.

Biomolecules, Journal Year: 2022, Volume and Issue: 12(10), P. 1429 - 1429

Published: Oct. 6, 2022

Brain neurodegenerative diseases (BND) are debilitating conditions that especially characteristic of a certain period life and considered major threats to human health. Current treatments limited, meaning there is challenge in developing new options can efficiently tackle the different components pathophysiological processes these conditions. The renin-angiotensin-aldosterone system (RAS) an endocrine axis with important peripheral physiological functions such as blood pressure cardiovascular homeostasis, well water sodium balance systemic vascular resistance—functions which well-documented. However, recent work has highlighted paracrine autocrine RAS tissues, including central nervous (CNS). It known hyperactivation pro-inflammatory pro-oxidant effects, thus suggesting its pharmacological modulation could be used management present paper underlines involvement pathophysiology BNDs Parkinson’s disease (PD), Alzheimer’s (AD), multiple sclerosis (MS), Huntington’s (HD), motor neuron (MND), prion (PRD), identification drugs pharmacologically active substances act upon RAS, alleviate their symptomatology or evolution, thus, contribute novel therapeutic approaches.

Language: Английский

Citations

14

Sleep Quality Mediates the Effect of Sensitization-Associated Symptoms, Anxiety, and Depression on Quality of Life in Individuals with Post-COVID-19 Pain DOI Creative Commons
Juan C. Pacho-Hernández, César Fernández‐de‐las‐Peñas, Stella Fuensalida‐Novo

et al.

Brain Sciences, Journal Year: 2022, Volume and Issue: 12(10), P. 1363 - 1363

Published: Oct. 8, 2022

A better understanding of biological and emotional variables associated with health-related quality life in people long-COVID is needed. Our aim was to identify potential direct indirect effects on the relationships between sensitization-associated symptoms, mood disorders such as anxiety/depressive levels, sleep suffering from post-COVID-19 pain. One hundred forty-six individuals who were hospitalized due COVID-19 during first wave pandemic long-term pain completed different patient-reported outcome measures (PROMs), including clinical features, symptoms sensitization central nervous system (Central Sensitization Inventory), (Hospital Anxiety Depressive Scale), (Pittsburgh Sleep Quality Index), (paper-based five-level version EuroQol-5D) a face-to-face interview conducted at 18.8 (SD 1.8) months after hospitalization. Different mediation models assess associations among variables. The revealed that depressive levels directly affected life; however, these not statistically significant when included. In fact, effect symptomatology (β = -0.10, 95% CI -0.1736, -0.0373), (β= -0.09, -0.1789, -0.0314), anxiety -0.1648, -0.0337) all indirectly mediated by quality. This study mediates relationship (depressive/anxiety levels) reporting Longitudinal studies will help determine implications findings.

Language: Английский

Citations

14

Gastrointestinal disorders in post-COVID syndrome. Clinical guidelines DOI Creative Commons
В. Б. Гриневич, Л. Б. Лазебник, Yu. A. Kravchuk

et al.

Experimental and Clinical Gastroenterology, Journal Year: 2023, Volume and Issue: 12, P. 4 - 68

Published: May 20, 2023

Summary Post- COVID syndrome refers to the long-term consequences of a new coronavirus infection COVID-19, which includes set symptoms that develop or persist after COVID-19. Symptoms gastrointestinal disorders in post- syndrome, due chronic infl ammation, organ damage, prolonged hospitalization, social isolation, and other causes, can be persistent require multidisciplinary approach. The presented clinical practice guidelines consider main preventive therapeutic diagnostic approaches management patients with gastroenterological manifestations postCOVID syndrome. Guidelines were approved by 17th National Congress Internal Medicine 25th Gastroenterological Scientifi c Society Russia.

Language: Английский

Citations

9