Small,
Journal Year:
2023,
Volume and Issue:
19(48)
Published: July 30, 2023
Although
protein
imprinted
materials
with
multiple
templates
are
developed
to
selectively
separate
different
proteins,
it
is
difficult
achieve
the
programmed
adsorption
and
separation
of
proteins
using
one
material,
because
available
constructed
through
irreversible
crosslinking
their
structures
unprogrammable
non-reconstructive.
Herein,
a
novel
nanosphere
(MS@PTL-g-PNIPAM)
designed,
which
not
only
temperature
pH
responsive
but
also
can
dynamically
reversibly
crosslink/de-crosslink
under
ultraviolet
light
wavelengths.
With
help
reversible
photo-crosslinking,
nanospheres
be
repeatedly
into
toward
target
proteins.
Moreover,
prepared
easily
controlled
rebinding
release
benefiting
from
introduced
temperature-
pH-responsive
moieties.
As
consequence,
this
study
realizes
specific
mixture
real
bovine
blood
sequentially
by
programming
material.
It
resource
saving,
time
recyclable,
will
provide
convenience
for
use
in
purification,
drug
delivery,
virus
detection.
Deleted Journal,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 20, 2025
Abstract
Stimuli‐responsive
molecularly
imprinted
polymers
(MIPs)
are
exciting
smart
materials
that
gaining
substantial
interest
within
the
research
community
due
to
their
versatility
and
possible
widespread
applications
in
biosensing,
biomedicine
diagnostics,
as
well
chromatography
separation
sciences.
These
offer
significant
advantages
recognition
over
biological
counterparts
(antibodies)
because
of
ease
low
cost
production
along
with
robustness
resistance
extremes
temperature
pH.
This
much
needed
review
aims
provide
an
updated
summary
various
stimuli‐responsive
MIPs
reported
date
including
those
relying
on
thermo,
pH,
photo,
biomolecule,
ion,
magnetic
electrical
stimuli
includes
design
synthesis.
The
also
explores
potential
MIPs,
particularly
fields
biosensors
imaging,
drug
delivery,
disease
treatments
interventions
targets
from
complex
media.
disadvantages
current
set
out
review,
allows
for
researchers
gather
a
concise
understanding
these
smart‐materials
should
pave
way
new
methods
development
real‐world
applications.
We
believe
is
helpful
necessary
guide
future
evolution
application
MIPs.
Journal of Nanobiotechnology,
Journal Year:
2025,
Volume and Issue:
23(1)
Published: March 6, 2025
Microbial
keratitis,
a
sight-threatening
corneal
infection,
remains
significant
global
health
concern.
Conventional
therapies
using
antimicrobial
agents
often
suffers
from
limitations
such
as
poor
drug
penetration,
side
effects,
and
occurrence
of
resistance,
with
prognosis.
Novel
treatment
techniques,
their
unique
properties
targeted
delivery
capabilities,
offers
promising
solution
to
overcome
these
challenges.
This
review
delves
into
timely
update
the
state-of-the-art
advance
therapeutics
for
keratitis
treatment.
The
diverse
microbial
origins
including
viral,
bacterial,
fungal
infections,
exploring
complex
pathogenic
mechanisms,
followed
by
resistance
mechanisms
in
pathogens
are
reviewed
briefly.
Importantly,
emerging
therapeutic
techniques
piezodynamic
therapy,
photothermal
photodynamic
nanoenzyme
metal
ion
therapy
summarized
this
showcasing
potential
traditional
treatments.
challenges
future
directions
nanotechnology-based
approaches
discussed,
focusing
on
safety,
targeting
strategies,
combination
therapies.
aims
inspire
researchers
revolutionize
accelerate
development
functional
materials
different
ACS Omega,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 11, 2025
In
order
to
maintain
the
stability
of
structure
protein
molecules
and
improve
recognition
during
separation
process,
molecular
imprinting
technology
is
combined
with
freeze
polymerization
synthesize
cryogels
(MICs).
This
study
uses
bovine
serum
albumin
(BSA)
as
a
template
protein,
low
critical
cosolubility
temperature
(LCST)-type
ionic
liquids
temperature-sensitive
functional
monomers,
imidazole
liquids,
acrylamides
auxiliary
monomers
prepare
MICs
specific
recognition,
sensitivity,
interpenetrating
macroporous
structure,
large
surface
area.
The
prepared
at
freezing
have
uniform
structures
good
mechanical
properties,
which
conducive
improvement
mass
transfer
adsorption
capacities.
Due
advantages,
MIC
reaches
equilibrium
within
125
min
saturated
capacity
741.5
mg
g-1
an
factor
1.65.
Their
static
dynamic
behaviors
are
more
in
line
Langmuir
model
quasi-secondary
kinetic
model,
respectively.
addition,
has
obvious
maximum
amount
reached
37
°C.
(relative
cytochrome
c,
blood
hemoglobin,
lysozyme)
for
BSA
up
1.39.
Repeatability
experiments
reveal
that
molecularly
imprinted
retained
87%
after
five
adsorption-desorption
cycles,
indicating
excellent
recyclability
potential
practical
application.
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 26, 2024
Porous
polymers,
including
hydrogels,
covalent
organic
frameworks
(COFs),
and
hyper
crosslinked
polymers
(HCPs),
have
become
essential
in
biomedical
research
for
their
tunable
pore
architectures,
large
surface
areas,
functional
versatility.
This
review
provides
a
comprehensive
overview
of
classification
updated
synthesis
mechanisms,
such
as
3D
printing,
electrospinning,
molecular
imprinting.
Their
pivotal
roles
drug
delivery,
tissue
engineering,
wound
healing,
photodynamic/photothermal
therapies,
focusing
on
how
size,
distribution,
architecture
impact
release,
cellular
interactions,
therapeutic
outcomes,
are
explored.
Key
challenges,
biocompatibility,
mechanical
strength,
controlled
degradation,
scalability,
critically
assessed
alongside
emerging
strategies
to
enhance
clinical
potential.
Finally,
recent
challenges
future
perspectives,
emphasizing
the
broader
applications
porous
addressed.
work
valuable
insights
advancing
next-generation
innovations
through
these
materials.
Nano Select,
Journal Year:
2024,
Volume and Issue:
5(11)
Published: June 27, 2024
ABSTRACT
The
ineffectiveness
of
traditional
wastewater
treatment
procedures
to
completely
remove
them
results
in
their
release
into
the
environment.
There
is
a
pressing
need
pharmaceuticals
effectively
using
different
methods.
Using
affordable
technologies
while
maintaining
standards
for
health
and
safety
one
main
problems
industry.
In
this
study,
cost
effective
highly
selective
molecularly
imprinted
polymers
(MIPs)
was
combined
with
silver
nanoparticles
(AgNPs)
capped
platanus
acerifolia
(PL)
moringa
oleifera
(MO)
removal
sulfamethoxazole,
nevirapine
ibuprofen
wastewater.
Moreover,
study
focused
on
adsorption
parameters,
including
temperature,
pH,
adsorbent
dosage,
adsorbate
concentration,
contact
time.
transmission
electron
microscopy
revealed
that
MO/PL‐AgNPs
MO/PL‐nanoMIPs
are
nanosized
spherical.
XRD
confirmed
formation
AgNPs
onto
surface.
Adsorption
isotherms
fitted
linear
Langmuir
model.
However,
high
Q
max
values
were
obtained
compared
MO/PL‐AgNPs.
pseudosecond
order
second‐order
kinetic
model
best
MO/PL‐nanoMIPs,
thermodynamics
process
spontaneous
endothermic.
findings
first
time
efficiency
selected
target
