Antibacterial Properties of Copper Oxide Nanoparticles (Review)

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(21), P. 11563 - 11563

Published: Oct. 28, 2024

The use of metal and oxide nanoparticles is frequently regarded as a potential solution to the issue bacterial antibiotic resistance. Among proposed range with antibacterial properties, copper are particular interest. Although properties have been known for considerable period time, studies on effects nanomaterials respect biological systems attracted attention in recent years. This review presents summary nanoparticles, mechanisms by which effect realized, key reported methods modifying these improve their activity. A comparative analysis effectiveness presented depending type microorganism, shape Gram classification bacteria based data from published sources. In addition, addresses activities including antifungal cytotoxic well “antioxidant” According conducted literature data, it can be concluded that significant bacteriostatic wide microorganisms and, some cases, contribute inhibition fungal growth. At same sensitivity Gram-positive was often higher than Gram-negative bacteria.

Language: Английский

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Screening for Chemical Characterization and Pharmacological Properties of Different Extracts from Nepeta italica

Plants, Journal Year: 2023, Volume and Issue: 12(15), P. 2785 - 2785

Published: July 27, 2023

Plants from the Nepeta genus have been proved to possess different pharmacological properties, among which are antimicrobial, antioxidant, anti-inflammatory, analgesic, and cytotoxic effects. italica is a medicinal plant traditionally used for its analgesic effects, in present study, phytochemical composition biological effects of hexane, dichloromethane (DCM), ethyl acetate (EA), ethanol, ethanol-water, water extracts aerial parts were investigated determining phenolic composition, antioxidant anti-inflammatory isolated mouse colon specimens exposed lipopolysaccharide (LPS). Polar richest terms compounds, especially rosmarinic acid. In parallel, also most effective as scavenging/reducing enzyme inhibition agents, towards cholinesterases α-glucosidase, inhibiting LPS-induced cyclooxygenase-2 (COX-2) tumor necrosis factor α (TNFα) gene expression colon. This poses basis future vivo investigations confirming protective polar N. against inflammatory bowel diseases.

Language: Английский

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How to Naturally Support the Immune System in Inflammation—Essential Oils as Immune Boosters

Biomedicines, Journal Year: 2023, Volume and Issue: 11(9), P. 2381 - 2381

Published: Aug. 25, 2023

Efficient functionality of the immune system is needed to fight against development infectious diseases, including, among others, serious recurrent chronic infections. Research has shown that many modern common such as inflammatory bowel diseases and cardiovascular e.g., thromboembolism, cancer, obesity, or depression, are connected with processes. Therefore, new, good stimulators system’s response sought. They include synthetic compounds well biological preparations lipopolysaccharides, enzymes, bacterial metabolites, secondary metabolites plants, demonstrating a multidirectional effect. Essential oils characterized by invaluable activities, including antimicrobial, antioxidant, anti-inflammatory, immunostimulating. may stimulate via utilization their constituents, antibodies, cytokines, dendritic cells. Some essential proliferation immune-competent cells, polymorphonuclear leukocytes, macrophages, natural killer B T lymphocytes. This review focused on ability affect system. It also possible oil components positively interact recommended anti-inflammatory antimicrobial drugs. Thus, there need explore synergies between active ingredients for medical use.

Language: Английский

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The Precious Potential of the Sacred Tree Chamaecyparis obtusa (Siebold & Zucc.) Endl. as a Source of Secondary Metabolites with Broad Biological Applications

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(5), P. 2723 - 2723

Published: Feb. 27, 2024

Chamaecyparis obtusa (Siebold & Zucc.) Endl., which belongs to the Cupressaceae family, occurs naturally in North America and Asia, especially Korea, Taiwan Japan, where it is an evergreen, coniferous, sacred, ethnic tree. It has many useful varieties that are widespread throughout world grown for decorative purposes. most commonly used as ornamental plant homes, gardens or parks. also widely areas of economy; example, its wood architecture well furniture production. In addition, oil extracted from increasingly cosmetology skin care. Due wide economic demand, mainly represents largest area plantation forest. Despite this, on red list endangered species. Its use ethnopharmacology led more research recent years attempt elucidate potential mechanisms various biological activities, such antimicrobial, antioxidant, anticancer, antidiabetic, antiasthmatic, anti-inflammatory, antiallergic, analgesic central nervous system effects. been shown can be insect repellent ingredient disease treatment. This thesis provides a comprehensive review studies date, looking at different fields obtusa.

Language: Английский

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Environmental Factors Related to Climate Change Alter the Chemical Composition and Biological Activity of Lavandula viridis L’Hér Essential Oil

Agriculture, Journal Year: 2024, Volume and Issue: 14(7), P. 1067 - 1067

Published: July 2, 2024

Climate change is affecting all regions of the world, and Mediterranean region one most affected. Plants accumulate secondary metabolites as an adaptive response to stress circumstances. The present study investigated effect different abiotic factor conditions (drought, moderate heat, severe salinity, UV-B radiation) on essential oil (EO) yield, composition (volatile profile), biological activity (enzyme inhibition antioxidant activity) Lavandula viridis L’Hér. In general, environmental increased extraction yield EO. Eighty-two compounds were identified in EO factors induced some quantitative changes composition. Severe heat salinity concentration two abundant compounds, 1,8-cineole camphor. also potential inhibit enzymes butyrylcholinesterase tyrosinase. Drought, radiation promoted ability acetylcholinesterase. addition, drought enhanced These results are relevant for exploring this industrial applications, although future studies combining studied important understand influence synergistic effects bioactivity plant products obtained.

Language: Английский

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In vitro synergistic antibacterial activities of carvacrol, thymol and selected carvacrol-rich and carvacrol-deficient essential oil combinations

Journal of Essential Oil Bearing Plants, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 16

Published: April 9, 2025

Language: Английский

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Essential oils from the medicinal plants of Africa

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 159 - 249

Published: Jan. 1, 2025

Language: Английский

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Allelopathy and Allelochemicals in Chamaecyparis obtusa Leaves for the Development of Sustainable Agriculture

Agronomy, Journal Year: 2024, Volume and Issue: 14(7), P. 1557 - 1557

Published: July 17, 2024

Chamaecyparis obtusa (Siebold et Zucc.) Endl. is cultivated in the temperate region of East Asia for its high-quality and profitable timber. The timber-processing industry produces a large amount waste, such as tree bark, branches, leaves, finding ways to minimize waste economically environmentally efficient. In present study, allelopathic activity allelochemicals C. leaves were investigated develop potential application methods. phytotoxic associated leaf extracts significantly suppressed growth weeds; Echinochloa crus-galli, Phleum pratense Lolium multiflorum under laboratory conditions. powder applied onto soil surface also germination E. crus-galli P. greenhouse Hinokiic acid (+)-dihydrosesamin isolated from structurally identified. Both compounds cress concentration dependent manner. When obtua additive, hinokiic potentially cause inhibitory by leaching into soil. These experiments showed that are phytotoxic. demonstrated have against several plant species, produce allelochemicals. Therefore, may be useful weed suppression purposes. biomass frequently timber processing significant waste. development control products using solution reduce environmental impact provide economic value. However, material should evaluated herbicidal additive possible foliar spray field

Language: Английский

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Chemical characterization and biological abilities of Anthocleista djalonensis collected from two locations of Ivory Coast

eFood, Journal Year: 2023, Volume and Issue: 4(4)

Published: July 4, 2023

Abstract In this study, the total phenolic and flavonoid contents, HPLC‐DAD detected phytochemicals, antioxidant enzyme inhibitory potential of methanolic aqueous (as infusion) extracts medicinal plant, Anthocleista djalonensis (leaf stem bark) collected from two locations, Mafiblé Prikro, in Ivory Coast, were investigated. The ranges contents obtained 14.17–46.95 mg gallic acid equivalent (GAE)/g 2.96–34.76 rutin (RE)/g, respectively. Antioxidant abilities terms radical scavenging, reducing metal chelating activity different assays as follows: DPPH (4.90–48.82 trolox [TE]/g), ABTS (21.05–81.89 TE/g), CUPRAC (29.54–122.33 FRAP (17.53–94.06 TE/g) (10.09–28.49 EDTAE/g. A. Mafiblé, especially those bark, contained higher level bioactive compared to Prikro extracts, by high‐performance liquid chromatography with photodiode‐array detection (HPLC‐DAD). Only irrespective plant parts/location, showed inhibition against acetylcholinesterase (1.42–2.12 galantamine (GALAE)/g), while only bark extract was found inhibit butyrylcholinesterase (0.65 GALAE/g). Thus, findings study could be useful for better application benefits plant.

Language: Английский

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Chamaecyparis lawsoniana Leaf Essential Oil as a Potential Anticancer Agent: Experimental and Computational Studies

Plants, Journal Year: 2023, Volume and Issue: 12(13), P. 2475 - 2475

Published: June 28, 2023

Cancer remains one of the leading causes death worldwide, affected by several factors including oxidative stress; and although conventional synthetic medicines have been used to treat cancer, they often result in various side effects. Consequently, there is a growing need for newer, safer more effective alternatives, such as natural plant products. Essential oils (EOs) are alternative, offering wide range bioactivities, antibacterial, antiviral, antioxidant, anticancer properties. Accordingly, objective present study was investigate chemical composition, well antioxidant properties leaf essential oil Chamaecyparis lawsoniana (CLLEO) belonging Cupressaceae family. Totally, 59 constituents were identified gas chromatography-mass spectrometry (GC-MS) analysis. cis-Abienol, trans-ferruginol, α-cadinol, δ-muurolene α-pinene major components. The vitro cytotoxicity against human breast (MCF-7), colon (HCT-116), lung (A-549), hepatocellular (HepG-2) carcinoma cells using MTT assay indicated promising cytotoxic activity all tested cancer cells, particularly HepG-2, with significant selectivity indices. CLLEO exhibited weak according DPPH, ABTS FRAP assays. In silico docking these epidermal growth factor receptor (EGFR), myeloid cell leukemia-1 (Mcl-1) caspase-8 Molecular Operating Environment (MOE) software demonstrated good binding affinities components active site targets. These findings suggested CLLEO, or its individual components, potentially viable therapeutic option managing cancerous conditions.

Language: Английский

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