Chemical Exposomics in Human Plasma by Lipid Removal and Large-Volume Injection Gas Chromatography–High-Resolution Mass Spectrometry DOI Creative Commons
Hongyu Xie, Kalliroi Sdougkou, Bénilde Bonnefille

et al.

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(40), P. 17592 - 17605

Published: Sept. 24, 2024

For comprehensive chemical exposomics in blood, analytical workflows are evolving through advances sample preparation and instrumental methods. We hypothesized that gas chromatography-high-resolution mass spectrometry (GC-HRMS) could be enhanced by minimizing lipid coextractives, thereby enabling larger injection volumes lower matrix interference for improved target sensitivity nontarget molecular discovery. A simple protocol was developed small plasma (100-200 μL) using isohexane (H) to extract supernatants of acetonitrile-plasma (A-P). The HA-P method quantitative a wide range hydrophobic multiclass analytes (i.e., log

Language: Английский

Efficient biodegradation of plastics additive Tris 2,4-di-tert-butylphenyl phosphite by synthetic consortia based on relay biodegradation principal DOI

Malle Adolf -,

Farees Ud Din Mufti,

Wei Hong

et al.

Total environment engineering., Journal Year: 2025, Volume and Issue: unknown, P. 100010 - 100010

Published: Feb. 1, 2025

Language: Английский

Citations

0

Development of a dispersive liquid–liquid microextraction method for the determination of plastic additives in seawater DOI Creative Commons
María-José González-Castro,

Jaime Uribe-Ares,

Soledad Muniategui‐Lorenzo

et al.

Analytical Methods, Journal Year: 2024, Volume and Issue: 16(11), P. 1603 - 1610

Published: Jan. 1, 2024

A method using DLLME prior to HPLC-DAD was developed determine seven additives from the plastics industry (butylated hydroxytoluene, diisodecyl phthalate, irgafos 168, lawsone, quercetin, triclosan and vitamin E) in seawater samples.

Language: Английский

Citations

2

Quantification of Irgafos P-168 and Degradative Profile in Samples of a Polypropylene/Polyethylene Composite Using Microwave, Ultrasound and Soxhlet Extraction Techniques DOI Open Access
Joaquín Hernández‐Fernández,

Jaime Pérez-Mendoza,

Rodrigo Ortega‐Toro

et al.

Journal of Composites Science, Journal Year: 2024, Volume and Issue: 8(4), P. 156 - 156

Published: April 21, 2024

In polypropylene/polyethylene composite (C-PP/PE) production, stabilizing additives such as Irgafos P-168 are essential antioxidant agents. this study, an investigation was carried out that covers different solid–liquid extraction methods (Soxhlet, ultrasound, and microwaves); various variables were evaluated, temperature, time, the choice of solvents, type C-PP/PE used, gas chromatography coupled to mass spectrometry (GC-MS) technique used quantify presence in samples. The results revealed microwave most effective recovering P-168. A recovery 96.7% achieved when using dichloromethane a solvent, 92.83% limonene solvent. ultrasound recovered 91.74% 89.71% limonene. Soxhlet method showed lowest percentages 57.39% solvent 55.76% with limonene, especially form pellets. degradation products obtained highest Bis (di-test-butyl phenyl) phosphate Mono PP film. Finally, possible mechanisms for forming compounds postulated.

Language: Английский

Citations

1

Use of a nanoplastic carrier for assessing the aquatic toxicity of an organo-phosphite polymer additive DOI Creative Commons
Marica Erminia Schiano, Carlos Edo, Enrique Blázquez‐Blázquez

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: 361, P. 124837 - 124837

Published: Aug. 28, 2024

This work reports the production of nanoplastics (NPs) from polypropylene (PP) free antioxidant Irgafos® 168 (IRG) and alkane oligomers (ALK). PP pellets were milled into a powder with particle sizes in 100-500 μm range. Additives removed using dichloromethane, exposed to UV irradiation, followed by filtration through 1 filters. suspensions, oligomers, reloaded IRG ALK their original commercial concentrations. approach allowed testing aquatic toxicity at concentrations compromised water solubility limits. Toxicity assays cladoceran Daphnia magna 24-48 h immobilization neonates as endpoint showed for NPs containing IRG, EC

Language: Английский

Citations

0

Chemical Exposomics in Human Plasma by Lipid Removal and Large-Volume Injection Gas Chromatography–High-Resolution Mass Spectrometry DOI Creative Commons
Hongyu Xie, Kalliroi Sdougkou, Bénilde Bonnefille

et al.

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(40), P. 17592 - 17605

Published: Sept. 24, 2024

For comprehensive chemical exposomics in blood, analytical workflows are evolving through advances sample preparation and instrumental methods. We hypothesized that gas chromatography-high-resolution mass spectrometry (GC-HRMS) could be enhanced by minimizing lipid coextractives, thereby enabling larger injection volumes lower matrix interference for improved target sensitivity nontarget molecular discovery. A simple protocol was developed small plasma (100-200 μL) using isohexane (H) to extract supernatants of acetonitrile-plasma (A-P). The HA-P method quantitative a wide range hydrophobic multiclass analytes (i.e., log

Language: Английский

Citations

0