Effects of secondary metabolites on pollination in legume forage crops DOI Creative Commons
Mehmet Arif ÖZYAZICI

Ege Üniversitesi Ziraat Fakültesi Dergisi, Journal Year: 2023, Volume and Issue: 60(3), P. 539 - 552

Published: Oct. 12, 2023

Bitkiler, otoburlara karşı toksik, itici ve/veya beslenme karşıtı etkileri olan sekonder metabolitlerin sentezini içeren bir dizi savunma stratejisi geliştirmişlerdir. Genel olarak flavonoidler, alkaloidler ve terpenoidler sınıfında yer alan bu metabolitlerin, bitki savunmasındaki ekolojik işlevi iyi bilinmekte; ancak, bitki-tozlayıcı etkileşimlerindeki rolleri henüz yeterince açık değildir. Mevcut bilgilere göre, çiçeğin nektar poleninde bulunan metabolitler; renk koku gibi cezbedici özellikleri ile tozlaşmada aracılık etme, çok fazla katkısı olmayan böceklerden çiçeği nektarı koruma mikrobiyal aktiviteleri sayesinde tozlayıcılardaki hastalık etmenlerinin seviyesini azaltma faydaları etkili olmaktadır. Bu derleme çalışmasında, baklagil yem bitkilerindeki tozlaşmadaki üzerinde durulmuştur.

Innovative strategy for full-scale polar components explicition and ultrasonic-assisted optimization of Astragalus membranaceus flower DOI Creative Commons
Yumei Wang,

GU Mei-ling,

Meng Zhang

et al.

Ultrasonics Sonochemistry, Journal Year: 2025, Volume and Issue: 114, P. 107238 - 107238

Published: Jan. 25, 2025

Language: Английский

Citations

1
Astragalus membranaceus: A Traditional Chinese Medicine with Multifaceted Impacts on Breast Cancer Treatment DOI Creative Commons

Zhong Tang,

Xuefei Tian

Biomolecules, Journal Year: 2024, Volume and Issue: 14(10), P. 1339 - 1339

Published: Oct. 21, 2024

Breast cancer, the most prevalent malignant tumor among women globally, remains a critical area of focus for researchers striving to refine therapeutic approaches. As an important component traditional Chinese medicine,

Language: Английский

Citations

4
Simultaneously phytochemical characteristic interpretation and efficient extraction of bioactive polar substances in Phragmites australis DOI
Yumei Wang,

GU Mei-ling,

Yong Chol Han

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113880 - 113880

Published: May 1, 2025

Language: Английский

Citations

0
Diabetes cardiomyopathy: targeted regulation of mitochondrial dysfunction and therapeutic potential of plant secondary metabolites DOI Creative Commons

Xianglong Pan,

Erwei Hao, Fan Zhang

et al.

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: July 9, 2024

Diabetic cardiomyopathy (DCM) is a specific heart condition in diabetic patients, which major cause of failure and significantly affects quality life. DCM manifested as abnormal cardiac structure function the absence ischaemic or hypertensive disease individuals with diabetes. Although development involves multiple pathological mechanisms, mitochondrial dysfunction considered to play crucial role. The regulatory mechanisms mainly include dynamics, oxidative stress, calcium handling, uncoupling, biogenesis, mitophagy, insulin signaling. Targeting treatment has attracted increasing attention. Studies have shown that plant secondary metabolites contribute improving alleviating DCM. This review outlines role pathogenesis discusses mechanism for dysfunction. In addition, it also summarizes strategies based on metabolites. These targeting may help prevent treat

Language: Английский

Citations

3
Comparison and Characterization of Polysaccharides From Various Sources and Before and After Honey Processing of Astragali Radix Utilizing Saccharide Mapping DOI
Aoli Shang, Yadong Li, Ying Zhao

et al.

Biomedical Chromatography, Journal Year: 2025, Volume and Issue: 39(7)

Published: May 26, 2025

ABSTRACT This study aimed to investigate the differences in polysaccharides Astragali Radix (AR) from different sources, as well before and after honey processing, through analysis of enzymatic hydrolysates. The hydrolysis product astragalus (APS) by β‐galactosidase was characterized using hydrophilic interaction ultra‐high‐performance liquid chromatography coupled with time‐of‐flight mass spectrometry (HILIC‐UHPLC‐QTOF/MS). results indicated that all oligosaccharide fragments were composed hexoses, sugar groups linked 1,6‐glycosidic bonds. APS hydrolysates fingerprints established high‐performance an evaporative light scattering detector (HILIC‐HPLC‐ELSD) comprehensively evaluated based on their similarity. Semi‐quantitative each hydrolysate performed, combined partial least squares discriminant (PLS‐DA) significance testing further analyze main differential AR growth modes processing. Glucose oligosaccharides degree polymerization (DP) 5 6 identified indicators distinguish modes. can serve indicator raw honey‐processed (HAR). quality evaluation saccharide mapping, providing a reference for development standards AR.

Language: Английский

Citations

0
Unveiling the Mechanisms and Therapeutic Effects of Xiaoyao Sanjie Decoction in Triple-Negative Breast Cancer: A Network Pharmacology and Experimental Validation Approach DOI Creative Commons
Yu Qi,

Bo Xu,

Jinrong He

et al.

Drug Design Development and Therapy, Journal Year: 2024, Volume and Issue: Volume 18, P. 6263 - 6281

Published: Dec. 1, 2024

Triple-negative breast cancer (TNBC) is a disease associated with high incidence and mortality, which major problem threatening women's health. Xiaoyao Sanjie Decoction (XYSJD) exhibits remarkable therapeutic efficacy on TNBC; however, the underlying mechanism unclear. This study verified of XYSJD its active component in treatment TNBC explored potential mechanism. Ultra-high performance liquid chromatography-hybrid quadrupole orbitrap mass spectrometry (UHPLC-Q Exactive HFX-MS) was applied to explore main chemical constituents XYSJD. The key targets mechanisms were predicted through network pharmacology, bioinformatics analysis molecular docking. effects against cells evaluated by CCK-8 assay, EdU wound healing transwell Hoechst-PI staining flow cytometry. action validated Western blot analysis. Finally, effect Que further tumor formation model. UHPLC-Q HFX-MS identified total 9 compounds Network pharmacological methods 206 for anti-TNBC. Bioinformatics suggests that EZH2/AKT1 signaling pathway might play an important role TNBC. Gene Ontology enrichment showed biological process mainly involved apoptosis. observed have good anticancer vivo vitro. In addition, quercetin could induce apoptosis decreased expression levels pathway. Furthermore, AKT1 overexpression, AKT activator (SC79) EZH2 overexpression reverse induced cells. revealed anti-TNBC Quercetin, effective XYSJD, promoted via blockade These findings aim provide more reliable basis clinical application

Language: Английский

Citations

1
Can Isoflavone-Rich Legume Plants Be Useful in the Chemoprevention of Hormone-Dependent Cancers?—A Systematic Review DOI Open Access

Wojciech Paździora,

Paweł Paśko, Karolina Grabowska

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(13), P. 7389 - 7389

Published: July 5, 2024

Plants from the

Language: Английский

Citations

0
Effects of secondary metabolites on pollination in legume forage crops DOI Creative Commons
Mehmet Arif ÖZYAZICI

Ege Üniversitesi Ziraat Fakültesi Dergisi, Journal Year: 2023, Volume and Issue: 60(3), P. 539 - 552

Published: Oct. 12, 2023

Bitkiler, otoburlara karşı toksik, itici ve/veya beslenme karşıtı etkileri olan sekonder metabolitlerin sentezini içeren bir dizi savunma stratejisi geliştirmişlerdir. Genel olarak flavonoidler, alkaloidler ve terpenoidler sınıfında yer alan bu metabolitlerin, bitki savunmasındaki ekolojik işlevi iyi bilinmekte; ancak, bitki-tozlayıcı etkileşimlerindeki rolleri henüz yeterince açık değildir. Mevcut bilgilere göre, çiçeğin nektar poleninde bulunan metabolitler; renk koku gibi cezbedici özellikleri ile tozlaşmada aracılık etme, çok fazla katkısı olmayan böceklerden çiçeği nektarı koruma mikrobiyal aktiviteleri sayesinde tozlayıcılardaki hastalık etmenlerinin seviyesini azaltma faydaları etkili olmaktadır. Bu derleme çalışmasında, baklagil yem bitkilerindeki tozlaşmadaki üzerinde durulmuştur.

Citations

0