Optimized framework for evaluating F3 transgressive segregants in cayenne pepper

BMC Plant Biology, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 6, 2025

Developing F3 transgenic segregants has significant potential to improve cayenne pepper varieties. However, current evaluation methods are often inconsistent and inaccurate, hindering the identification of effective traits. Traditional approaches only focus on a few aspects, thus not covering full performance genotype. Utilizing morphometric image processing categorical parameter assessment can fill gap traditional improving accuracy objectivity in evaluation. In addition, environmental factors affecting process adequately considered, making results unreliable. Therefore, systematic framework integrating analysis, assessment, correction is essential for optimizing transgressive segregants. The study aims develop synchronized selection approach based agronomic, fruit morphometric, traits evaluating This research was designed with randomized completed block design 16 segregant genotypes three check Each genotype repeated times, resulting 57 experimental units. Based this study, quantitative indices could be used selectively systematically evaluate peppers. index formed from outcome criteria, number productive branches, area, major axes weighted through an unbiased linear estimation approach, heritability, best path analysis. Seven demonstrated superior indices, G10.9.2, G10.7.1, G6.8.5 excelling both agronomic evaluations. These lines recommended yield hybrid cross-parents.

Language: Английский

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Metabolite profiling of some organs and the potential of Mukia javanica as an antihypertension

Frontiers in Sustainable Food Systems, Journal Year: 2025, Volume and Issue: 8

Published: Jan. 3, 2025

Mukia javanica is a close relative of the cucumber ( Cucumis sativus ) used to treat hypertension in Leuwiliang community. contains calcium, magnesium, potassium, and phosphorus, which help lower blood pressure. In contrast, content metabolite compounds that are useful for lowering pressure M. has not been previously reported. Therefore, this research aimed identify determine secondary contained several organs potential function treating hypertension. The method gas chromatography–mass spectrometry (GCMS) method. samples analyzed included , such as roots, stems, leaves, fruit. Several tested part plant with most compound content. Data analysis R version 3.5.2 program Metaboanalyst program. Based on test results, 98 were identified divided into classes, significant number was terpenoid group. 13-Tetradecen-1-acetate (root), Oleic acid (fruit), Phytol (stem), 4-hydroxy-3-nitrocoumarin (root) be antihypertensive. correlation analysis, metabolites Hexadecanoic Acid Methyl Ester, Squalene, Vitamin E, Stigmasta-7,16-Dien-3 show high values. Ester found all parts, it reported associated antihypertension antioxidants. future, raw material antihypertensive drugs.

Language: Английский

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Triterpenoid wax esters confirm Ficus religiosa in archaeological sequences within the Mayadevi temple shrine, Lumbini – the birthplace of Buddha

Frontiers in Geochemistry, Journal Year: 2025, Volume and Issue: 3

Published: March 6, 2025

Leaf wax biomarkers permit chemotaxonomic identification of past vegetation in archaeological contexts. At the birthplace Buddha, Lumbini Nepal, evidence a multi-phase tree shrine from earliest beginnings Buddhism has been uncovered sequences within Mayadevi Temple. As yet there no scientific attempt to establish species tree(s) occupying “central open space” ancient shrine, or wider sacred landscape, despite this being an issue significance for understanding early Buddhist practice. The cuticular leaf waxes three and venerated tradition - Saraca asoca , F. religiosa Shorea robusta were characterised, with additional achieved following hydrolysis triterpenoid esters. Diagnostic distributions esters observed leaves (β-amyrin, α-amyrin lupeol C 16:0 18:2 18:1 18:0 20:2 20:1 20:0, 22:0 fatty acids, Ψ-taraxasteryl eicosanoate, Ψ-taraxasterol behenate) S. (taraxeryl linoleate). Chronologically controlled contextualised analyses soil lipids characterise ester distribution main shrine’s space”, adjacent palaeo-channel, monastic site village mound. presence β-amyrin palmitate palmitate, longer-chain homologues (β-amyrin stearate, stearate eicosadienoate) indicate that occupied throughout development alongside grove close palaeo-channel Beyond these locations, occurred only rarely historic although are enhanced foundation pit occupation surface site; is biomarker other trees. long-standing South Asia; our analysis indicates its transition into religious culture demonstrates leaf-wax can provide visibility shrines Asia.

Language: Английский

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The Role of Triterpenoids in Gastric Ulcer: Mechanisms and Therapeutic Potentials

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(7), P. 3237 - 3237

Published: March 31, 2025

Gastric ulcer (GU) is a prevalent gastrointestinal disorder impacting millions worldwide, with complex pathogenic mechanisms that may progress to severe illnesses. Conventional therapies relying on anti-secretory agents and antibiotics are constrained by drug abuse increased bacterial resistance, highlighting the urgent need for safer therapeutic alternatives. Natural medicinal compounds, particularly triterpenoids derived from plants herbs, have gained significant attention in recent years due their favorable efficacy reduced toxicity profiles. Emerging evidence indicates exhibit potent anti-ulcer properties across various experimental models, modulating key pathways involved inflammation, oxidative stress, apoptosis, mucosal protection. Integrating current knowledge of these bioactive compounds facilitates development natural triterpenoids, addresses challenges clinical translation, deepens mechanistic understanding GU pathogenesis, drives innovation strategies GU. This review comprehensively evaluates research treatment since 2000, discussing biological sources, structural characteristics, pharmacological activities, action, animal models employed studies, limitations, associated application.

Language: Английский

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Exploring the Combined Efficacy of Carvacrol and Friedelin against Multi-Drug Resistant Bacteria in Upper and Lower Respiratory Tract Infections

Annals of Experimental and Molecular Biology, Journal Year: 2024, Volume and Issue: 6(1), P. 1 - 7

Published: Jan. 24, 2024

In the face of escalating antibiotic resistance, quest for alternative therapeutic strategies against multi-drug resistant (MDR) bacteria has become imperative. This study explores combined efficacy carvacrol and friedelin, derived from Nigella seed Sweet violet extracts, prevalent MDR implicated in upper lower respiratory tract infections. Employing a dose-dependent methodology across spectrum bacterial strains—E. coli, S. aureus, P. aeruginosa, K. pneumonia—our research evaluates antibacterial potential these natural compounds comparison to conventional treatments, notably ciprofloxacin. Results demonstrated significant increase zones inhibition with methanolic extracts exhibiting superior activity, particularly aureus E. suggesting potent mechanism action capable targeting specific cell structures or metabolic pathways. Notably, at higher concentrations, outperformed ciprofloxacin, underscoring their as viable alternatives adjuncts combating not only contributes growing body evidence supporting use plant-derived but also underscores urgency further investigation into mechanisms, safety, clinical applications. Through this research, we affirm friedelin foundational elements developing new antimicrobial address pressing challenge resistance.

Language: Английский

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Antibacterial Properties of Phytochemicals Isolated from Leaves of Alstonia boonei and Aerial Parts of Ipomoea cairica

Natural Product Communications, Journal Year: 2024, Volume and Issue: 19(9)

Published: Sept. 1, 2024

Objective The leaves of Alstonia boonei and aerial parts Ipomoea cairica are used for treatment microbial infections among other ailments in African traditional medicine. aim this study was to investigate the antimicrobial phytochemicals A. validate their use Ugandan herbal Methods plant materials were separately extracted using a dichloromethane/methanol (1:1) solvent system subjected repeated chromatographic separation isolate pure compounds. chemical structures isolated compounds determined through 1 H NMR, 13 C NMR 2D (COSY, HSQC HMBC). antibacterial activity extracts assessed agar well diffusion method. Results Chromatographic fractionation yielded trans-fagaramide pentacyclic lupane-type triterpenoid, lupeol, from boonei, friedelin I. cairica. Trans-fagaramide identified first time genus while demonstrated activity, with showing minimum inhibitory concentration (MIC) 125 μg/mL against Pseudomonas aeruginosa 250 Staphylococcus aureus, Salmonella typhi Escherichia coli. Friedelin exhibited MIC coli aeruginosa, aureus typhi. Conclusion activities observed support by indigenous communities Uganda treating infections.

Language: Английский

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Food waste from Parkia biglobosa seed processing as a potential biomass resource for valorization

Frontiers in Sustainable Food Systems, Journal Year: 2024, Volume and Issue: 8

Published: Dec. 10, 2024

Introduction The valorization of agricultural waste from indigenous sub-Saharan African food processes remains underexplored. By-products the processing Parkia biglobosa seeds into condiments are often regarded as pollutants. This research assessed their potential for development in various industrial applications. Materials and methods study employed a standardized protocol adopted P. seed condiments, enabling quantification by-products generated percentage. A comparative analysis proximate mineral constituents dried condiment coat (testa) was conducted. Furthermore, phytochemical constituent effluents two stages characterized using qualitative quantitative methods, including Fourier-transform infrared spectroscopy (FTIR) gas chromatography–mass spectrometry (GC–MS). Results discussion results showed that 66.27% each 100 g processed used could be considered waste, with 23.19% 29.47% effluent(s). has moisture absorption is fibrous nature, confirmed by fiber analysis—15.03 ± 0.13% compared to 9.07 0.10% condiment. Both contained considerable amounts sustenance minerals. Effluents boiling process exhibited characteristic starchy effect on textiles. concentrated effluent first stage had chocolate-like aroma, sticky texture, dark-brown color second stage. FTIR indicated presence alcohols, alkenes, aromatic rings, carboxylic acids, amines samples. GCMS characterization reported specific fatty acids known health benefits. When premised waste-to-wealth initiative, quantified processing, this study, have applications across processes, food, cosmetics, pharmaceutical, agriculture, among others.

Language: Английский

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