Cited by Potassium hexafluorotitanate as a catalytic activator for direct amidation of carboxylic acids

Aryl Borane as a Catalyst for Dehydrative Amide Synthesis DOI

Amit Vinayak Gavit,

Sanjana S. Talekar,

Manoj V. Mane

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 30, 2025

Tris(pentafluorophenyl)borane B(C6F5)3·H2O is reported as a catalyst for dehydrative amidation of carboxylic acids and amines. This protocol applicable across wide range >35 substrates, including aromatic aliphatic amines acids, resulting in amides ≤92% yields. The scalability the reaction up to 10 mmol, along with synthesis drugs such ibuprofen amide, moclobemide, phenacetin, demonstrates industrial potential our protocol.

Language: Английский

Citations

An Electrochemical Design for a General Catalytic Carboxylic Acid Substitution Platform via Anhydrides at Room Temperature: Amidation, Esterification, and Thioesterification DOI

Jian Han,

Jacob J. Piane,

Hannah Gizenski

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 14, 2025

An original concept for catalytic electrochemical dehydration has enabled a suite of acid substitutions, including amidation, esterification, and thioesterification, through linchpin anhydride formed in situ. By avoiding stoichiometric dehydrating agents, this method addresses leading challenge organic synthesis green chemistry. It also proceeds without additives at room temperature, accesses diverse range product structures, is easily scaled, the first example peptide coupling temperature.

Language: Английский

Citations

Pyridine-borane complex catalysed thioesterification: the direct conversion of carboxylic acids to thioesters DOI

Ming-Chuan Wang,

Xueying Yang,

Jian‐Feng Zhou

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(52), P. 6671 - 6674

Published: Jan. 1, 2024

The direct thioesterification of carboxylic acids was catalysed by a pyridine–borane complex, and this protocol features broad substrate scope good functional group tolerance extends the utility complexes as new catalysts.

Language: Английский

Citations

Potassium hexafluorotitanate as a catalytic activator for direct amidation of carboxylic acids DOI

Aman Singh, P. Veeraraghavan Ramachandran

Journal of Fluorine Chemistry, Journal Year: 2024, Volume and Issue: 278, P. 110328 - 110328

Published: July 30, 2024

Language: Английский

Citations